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Challenges with advanced therapy medicinal products and how to meet them

Nature reviews. Drug discovery, 2010-03, Vol.9 (3), p.195-201

2010

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Development of a rapid chromatographic strip test for the pen-side detection of foot-and-mouth disease virus antigen

Journal of virological methods, 2001-08, Vol.96 (2), p.189-202

2001

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Improvement and development of rapid chromatographic strip-tests for the diagnosis of rinderpest and peste des petits ruminants viruses

Journal of virological methods, 2011-06, Vol.174 (1-2), p.42-46

2011

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Control of SHIV-89.6P-infection of cynomolgus monkeys by HIV-1 Tat protein vaccine

Nature medicine, 1999-06, Vol.5 (6), p.643-650

1999

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Neutralization of primary HIV-1 SF13 can be detected in extended incubation phase assays with sera from monkeys immunized with recombinant HIV-1 SF2 gp120

Vaccine, 2004-01, Vol.22 (5-6), p.747-754

2004

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Do Biological Medicinal Products Pose a Risk to the Environment?: A Current View on Ecopharmacovigilance

Drug safety, 2009-01, Vol.32 (11), p.995-1000

2009

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β -Chemokines and Neutralizing Antibody Titers Correlate with Sterilizing Immunity Generated in HIV-1 Vaccinated Macaques

Proceedings of the National Academy of Sciences - PNAS, 1998-09, Vol.95 (18), p.10803-10808

1998

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Influence of N-linked glycans in V4-V5 region of human immunodeficiency virus type 1 glycoprotein gp160 on induction of a virus-neutralizing humoral response

Journal of acquired immune deficiency syndromes and human retrovirology, 1996-07, Vol.12 (3), p.213-220

1996

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Comparison of Immunity Generated by Nucleic Acid-, MF59-, and ISCOM-Formulated Human Immunodeficiency Virus Type 1 Vaccines in Rhesus Macaques: Evidence for Viral Clearance

Journal of Virology, 1999-04, Vol.73 (4), p.3292-3300

1999

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Immunization with recombinant modified vaccinia virus Ankara can modify mucosal simian immunodeficiency virus infection and delay disease progression in macaques

Journal of general virology, 2002-04, Vol.83 (4), p.807-818

2002

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Long-standing protection of macaques against cell-free HIV-2 with a HIV-2 iscom vaccine

Journal of acquired immune deficiency syndromes (1988), 1994-06, Vol.7 (6), p.551-559

1994

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Neutralizing Antibody Response During Human Immunodeficiency Virus Type 1 Infection: Type and Group Specificity and Viral Escape

Journal of general virology, 1993-05, Vol.74 (5), p.855-863

1993

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Presentation of a foreign peptide on the surface of tomato bushy stunt virus

Journal of general virology, 1997-06, Vol.78 (6), p.1213-1217

1997

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The role of type-1 and type-2 T-helper immune responses in HIV-1 vaccine protection

Journal of medical primatology, 1998-04, Vol.27 (2-3), p.50-58

1998

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Comparison of protection afforded by whole virus ISCOM versus MDP adjuvanted formalin-inactivated SIV vaccines from IV cell-free or cell-associated homologous challenge

AIDS research and human retroviruses, 1992-08, Vol.8 (8), p.1507-1510

1992

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HIV-1 vaccine-induced immune responses which correlate with protection from SHIV infection: compiled preclinical efficacy data from trials with ten different HIV-1 vaccine candidates

Immunology letters, 1999-03, Vol.66 (1), p.189-195

1999

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Immune response to immunostimulatory complexes (ISCOMs) prepared from human immunodeficiency virus type 1 (HIV-1) or the HIV-1 external envelope glycoprotein (gp120)

Vaccine, 1989-10, Vol.7 (5), p.465-473

1989

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N-linked glycans in the CD4-binding domain of human immunodeficiency virus type 1 envelope glycoprotein gp160 are essential for the in vivo priming of T cells recognizing an epitope located in their vicinity

Virology (New York, N.Y.), 1996-01, Vol.215 (2), p.124-133

1996

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Azidocytidine is incorporated into RNA of 3T6 mouse fibroblasts

FEBS letters, 1985-12, Vol.193 (2), p.203-207

AKERBLOM, L

1985

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A recombinant prime, peptide boost vaccination strategy can focus the immune response on to more than one epitope even though these may not be immunodominant in the complex immunogen

Vaccine, 1997-10, Vol.15 (15), p.1661-1669

1997

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A colorimetric reverse transcriptase assay optimized for Moloney murine leukemia virus, and its use for characterization of reverse transcriptases of unknown identity

Journal of virological methods, 1998-11, Vol.75 (1), p.9-20

1998

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Neutralizing cross-reactive and non-neutralizing monoclonal antibodies to HIV-1 gp120

AIDS (London), 1990-10, Vol.4 (10), p.953-960

1990

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Induction of homologous virus neutralizing antibodies in guinea-pigs immunized with two human immunodeficiency virus type 1 glycoprotein gp120-iscom preparations. A comparison with other adjuvant systems

Vaccine, 1996-03, Vol.14 (4), p.344-352

1996

Volltextzugriff (PDF)

Monoclonal antibodies to native HIV type 1 reverse transcriptase and their interaction with enzymes from different subtypes

AIDS research and human retroviruses, 2000-09, Vol.16 (13), p.1281-1294

2000

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Vaccine protection against HIV-2 infection in cynomolgus monkeys

AIDS research and human retroviruses, 1991-03, Vol.7 (3), p.271-277

1991

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Challenges with advanced therapy medicinal products and how to meet them

Development of a rapid chromatographic strip test for the pen-side detection of foot-and-mouth disease virus antigen

Improvement and development of rapid chromatographic strip-tests for the diagnosis of rinderpest and peste des petits ruminants viruses

Control of SHIV-89.6P-infection of cynomolgus monkeys by HIV-1 Tat protein vaccine

Neutralization of primary HIV-1 SF13 can be detected in extended incubation phase assays with sera from monkeys immunized with recombinant HIV-1 SF2 gp120

Do Biological Medicinal Products Pose a Risk to the Environment?: A Current View on Ecopharmacovigilance

β -Chemokines and Neutralizing Antibody Titers Correlate with Sterilizing Immunity Generated in HIV-1 Vaccinated Macaques

Influence of N-linked glycans in V4-V5 region of human immunodeficiency virus type 1 glycoprotein gp160 on induction of a virus-neutralizing humoral response

Comparison of Immunity Generated by Nucleic Acid-, MF59-, and ISCOM-Formulated Human Immunodeficiency Virus Type 1 Vaccines in Rhesus Macaques: Evidence for Viral Clearance

Immunization with recombinant modified vaccinia virus Ankara can modify mucosal simian immunodeficiency virus infection and delay disease progression in macaques

Long-standing protection of macaques against cell-free HIV-2 with a HIV-2 iscom vaccine

Neutralizing Antibody Response During Human Immunodeficiency Virus Type 1 Infection: Type and Group Specificity and Viral Escape

Presentation of a foreign peptide on the surface of tomato bushy stunt virus

The role of type-1 and type-2 T-helper immune responses in HIV-1 vaccine protection

Comparison of protection afforded by whole virus ISCOM versus MDP adjuvanted formalin-inactivated SIV vaccines from IV cell-free or cell-associated homologous challenge

HIV-1 vaccine-induced immune responses which correlate with protection from SHIV infection: compiled preclinical efficacy data from trials with ten different HIV-1 vaccine candidates

Immune response to immunostimulatory complexes (ISCOMs) prepared from human immunodeficiency virus type 1 (HIV-1) or the HIV-1 external envelope glycoprotein (gp120)

N-linked glycans in the CD4-binding domain of human immunodeficiency virus type 1 envelope glycoprotein gp160 are essential for the in vivo priming of T cells recognizing an epitope located in their vicinity

Azidocytidine is incorporated into RNA of 3T6 mouse fibroblasts

A recombinant prime, peptide boost vaccination strategy can focus the immune response on to more than one epitope even though these may not be immunodominant in the complex immunogen

A colorimetric reverse transcriptase assay optimized for Moloney murine leukemia virus, and its use for characterization of reverse transcriptases of unknown identity

Neutralizing cross-reactive and non-neutralizing monoclonal antibodies to HIV-1 gp120

Induction of homologous virus neutralizing antibodies in guinea-pigs immunized with two human immunodeficiency virus type 1 glycoprotein gp120-iscom preparations. A comparison with other adjuvant systems

Monoclonal antibodies to native HIV type 1 reverse transcriptase and their interaction with enzymes from different subtypes

Vaccine protection against HIV-2 infection in cynomolgus monkeys

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