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New Tacrine−Huperzine A Hybrids (Huprines): Highly Potent Tight-Binding Acetylcholinesterase Inhibitors of Interest for the Treatment of Alzheimer's Disease

Journal of medicinal chemistry, 2000-11, Vol.43 (24), p.4657-4666

2000

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Synthesis, in Vitro Pharmacology, and Molecular Modeling of Very Potent Tacrine−Huperzine A Hybrids as Acetylcholinesterase Inhibitors of Potential Interest for the Treatment of Alzheimer's Disease

Journal of medicinal chemistry, 1999-08, Vol.42 (17), p.3227-3242

1999

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Interaction of a new potent anticholinesterasic compound (±)huprine X with muscarinic receptors in rat brain

Neuroscience letters, 2002-06, Vol.325 (2), p.103-106

2002

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Effects of (±)-huprine Y and (±)-huprine Z, two new anticholinesterasic drugs, on muscarinic receptors

Neuroscience letters, 2005-05, Vol.379 (2), p.106-109

2005

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Synthesis and evaluation of tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease

Bioorganic & medicinal chemistry, 1998-04, Vol.6 (4), p.427-440

1998

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Early Environmental Stimulation Produces Long-Lasting Changes on β-Adrenoceptor Transduction System

Neurobiology of learning and memory, 1995-07, Vol.64 (1), p.49-57

1995

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D2 dopamine receptors and modulation of spontaneous acetylcholine (ACh) release from rat striatal synaptosomes

British journal of pharmacology, 1997-09, Vol.122 (2), p.286-290

1997

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Action on noradrenergic transmission of an anticholinesterase: 9-amino-1,2,3,4-tetrahydroacridine

Neuropharmacology, 1995-04, Vol.34 (4), p.367-375

1995

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Sources of calcium and alpha 1-adrenoceptor-mediated contraction in rat tail artery

British journal of pharmacology, 1996-08, Vol.118 (8), p.2067-2072

1996

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Differential effects of physostigmine and 1,2,3,4-tetrahydro-9-aminoacridine on the β-adrenoceptor transduction system

European journal of pharmacology, 1993-03, Vol.245 (1), p.9-13

1993

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Endothelial modulation of alpha 1-adrenoceptor contractile responses in the tail artery of spontaneously hypertensive rats

British journal of pharmacology, 1996-10, Vol.119 (4), p.765-771

1996

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Study of the mechanism of the relaxant action of (+)‐glaucine in rat vas deferens

British journal of pharmacology, 1993-11, Vol.110 (3), p.943-948

1993

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Post-train administration of 9-amino-1,2,3,4-tetrahydroacridine enhances passive avoidance retention and decreases β-adrenoceptor-linked cyclic AMP formation in middle-aged rats

Brain research, 1992-07, Vol.586 (1), p.117-120

1992

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Acute effects of tetrahydroaminoacridine on β-adrenoceptor-linked cyclic AMP accumulation in brain of young and middle-aged rats

Neuroscience letters, 1991-10, Vol.132 (1), p.51-54

1991

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IgA ANTIBODIES TO CHLAMYDIA TRACHOMATIS AND SEMINAL PARAMETERS IN ASYMPTOMATIC INFERTILE MALES

Archives of andrology, 2001, Vol.46 (3), p.189-195

2001

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Different alpha1-adrenoceptor-induced inositol phosphate formation in the two portions of rat vas deferens

Naunyn-Schmiedeberg's archives of pharmacology, 2001-01, Vol.363 (1), p.11-15

2001

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Alpha 1-adrenoceptor vasoconstriction in the tail artery during ageing

British journal of pharmacology, 1997-07, Vol.121 (5), p.1017-1023

1997

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Unspecific increase of blood levels of angiotensin converting enzyme in chronic hemodialysis

Medicina (Buenos Aires), 1994, Vol.54 (2), p.183

1994

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DNA methylation of leptin and adiponectin promoters in children is reduced by the combined presence of obesity and insulin resistance

International Journal of Obesity, 2014-11, Vol.38 (11), p.1457-1465

2014

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Brain Targeted Gold Liposomes Improve RNAi Delivery for Glioblastoma

International journal of nanomedicine, 2020-01, Vol.15, p.2809-2828

2020

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Pediatric chest x-ray in covid-19 infection

European journal of radiology, 2020-10, Vol.131, p.109236-109236, Article 109236

2020

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Effect of Intra-arterial Alteplase vs Placebo Following Successful Thrombectomy on Functional Outcomes in Patients With Large Vessel Occlusion Acute Ischemic Stroke: The CHOICE Randomized Clinical Trial

JAMA : the journal of the American Medical Association, 2022-03, Vol.327 (9), p.826

2022

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A dual role for the RhoGEF Ephexin5 in regulation of dendritic spine outgrowth

Molecular and cellular neuroscience, 2017-04, Vol.80, p.66-74

2017

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Stenotrophomonas maltophilia healthcare-associated infections: identification of two main pathogenic genetic backgrounds

The Journal of hospital infection, 2017-06, Vol.96 (2), p.183-188

2017

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The Challenge of Immunoglobulin-G Subclass Deficiency and Specific Polysaccharide Antibody Deficiency – a Dutch Pediatric Cohort Study

Journal of clinical immunology, 2016-02, Vol.36 (2), p.141-148

2016

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New Tacrine−Huperzine A Hybrids (Huprines): Highly Potent Tight-Binding Acetylcholinesterase Inhibitors of Interest for the Treatment of Alzheimer's Disease

Synthesis, in Vitro Pharmacology, and Molecular Modeling of Very Potent Tacrine−Huperzine A Hybrids as Acetylcholinesterase Inhibitors of Potential Interest for the Treatment of Alzheimer's Disease

Interaction of a new potent anticholinesterasic compound (±)huprine X with muscarinic receptors in rat brain

Effects of (±)-huprine Y and (±)-huprine Z, two new anticholinesterasic drugs, on muscarinic receptors

Synthesis and evaluation of tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease

Early Environmental Stimulation Produces Long-Lasting Changes on β-Adrenoceptor Transduction System

D2 dopamine receptors and modulation of spontaneous acetylcholine (ACh) release from rat striatal synaptosomes

Action on noradrenergic transmission of an anticholinesterase: 9-amino-1,2,3,4-tetrahydroacridine

Sources of calcium and alpha 1-adrenoceptor-mediated contraction in rat tail artery

Differential effects of physostigmine and 1,2,3,4-tetrahydro-9-aminoacridine on the β-adrenoceptor transduction system

Endothelial modulation of alpha 1-adrenoceptor contractile responses in the tail artery of spontaneously hypertensive rats

Study of the mechanism of the relaxant action of (+)‐glaucine in rat vas deferens

Post-train administration of 9-amino-1,2,3,4-tetrahydroacridine enhances passive avoidance retention and decreases β-adrenoceptor-linked cyclic AMP formation in middle-aged rats

Acute effects of tetrahydroaminoacridine on β-adrenoceptor-linked cyclic AMP accumulation in brain of young and middle-aged rats

IgA ANTIBODIES TO CHLAMYDIA TRACHOMATIS AND SEMINAL PARAMETERS IN ASYMPTOMATIC INFERTILE MALES

Different alpha1-adrenoceptor-induced inositol phosphate formation in the two portions of rat vas deferens

Alpha 1-adrenoceptor vasoconstriction in the tail artery during ageing

Unspecific increase of blood levels of angiotensin converting enzyme in chronic hemodialysis

DNA methylation of leptin and adiponectin promoters in children is reduced by the combined presence of obesity and insulin resistance

Brain Targeted Gold Liposomes Improve RNAi Delivery for Glioblastoma

Pediatric chest x-ray in covid-19 infection

Effect of Intra-arterial Alteplase vs Placebo Following Successful Thrombectomy on Functional Outcomes in Patients With Large Vessel Occlusion Acute Ischemic Stroke: The CHOICE Randomized Clinical Trial

A dual role for the RhoGEF Ephexin5 in regulation of dendritic spine outgrowth

Stenotrophomonas maltophilia healthcare-associated infections: identification of two main pathogenic genetic backgrounds

The Challenge of Immunoglobulin-G Subclass Deficiency and Specific Polysaccharide Antibody Deficiency – a Dutch Pediatric Cohort Study

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