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Interspecies evaluation of a physiologically based pharmacokinetic model to predict the biodistribution dynamics of dendritic nanoparticles

PloS one, 2023-05, Vol.18 (5), p.e0285798-e0285798

2023

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Simulating pathways of subsurface oil in the Faroe–Shetland Channel using an ocean general circulation model

Marine pollution bulletin, 2017-01, Vol.114 (1), p.315-326

2017

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Astrocyte-mediated metaplasticity in the hippocampus: Help or hindrance?

Neuroscience, 2015-11, Vol.309, p.113-124

Jones, O.D

2015

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PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: Prediction of plasma concentration–time profiles in human by using the physiologically‐based pharmacokinetic modeling approach

Journal of pharmaceutical sciences, 2011-10, Vol.100 (10), p.4127-4157

2011

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High resolution study of the spatial distributions of abyssal fishes by autonomous underwater vehicle

Scientific reports, 2016-05, Vol.6 (1), p.26095-26095, Article 26095

2016

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Quantitative Evaluation of Dendritic Nanoparticles in Mice: Biodistribution Dynamics and Downstream Tumor Efficacy Outcomes

Molecular pharmaceutics, 2022-01, Vol.19 (1), p.172-187

2022

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A review of the International Seabed Authority database DeepData from a biological perspective: challenges and opportunities in the UN Ocean Decade

Database : the journal of biological databases and curation, 2023-03, Vol.2023

2023

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PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 4: Prediction of plasma concentration–time profiles in human from in vivo preclinical data by using the Wajima approach

Journal of pharmaceutical sciences, 2011-10, Vol.100 (10), p.4111-4126

2011

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Improving the Accuracy of Predicted Human Pharmacokinetics: Lessons Learned from the AstraZeneca Drug Pipeline Over Two Decades

Trends in pharmacological sciences (Regular ed.), 2020-06, Vol.41 (6), p.390-408

2020

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Comparative analysis of pattern, management and outcome of pre‐ versus postnatally diagnosed major congenital heart disease: a population‐based study

Ultrasound in obstetrics & gynecology, 2001-05, Vol.17 (5), p.380-385

2001

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Pharmacokinetic/Pharmacodynamic Analysis of Savolitinib plus Osimertinib in an EGFR Mutation-Positive, MET-Amplified Non-Small Cell Lung Cancer Model

Molecular cancer therapeutics, 2023-05, Vol.22 (5), p.679-690

2023

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A PKPD Case Study: Achieving Clinically Relevant Exposures of AZD5991 in Oncology Mouse Models

The AAPS journal, 2023-06, Vol.25 (4), p.66-66, Article 66

2023

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Mutation of a type II keratin gene (K6a) in pachyonychia congenita

Nature genetics, 1995-07, Vol.10 (3), p.363-365

1995

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Applications of Quantitative Systems Pharmacology in Model‐Informed Drug Discovery: Perspective on Impact and Opportunities

CPT: pharmacometrics and systems pharmacology, 2019-11, Vol.8 (11), p.777-791

2019

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The MET Inhibitor AZD6094 (Savolitinib, HMPL-504) Induces Regression in Papillary Renal Cell Carcinoma Patient-Derived Xenograft Models

Clinical cancer research, 2015-06, Vol.21 (12), p.2811-2819

2015

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Developing PreDICT – a fully integrated data platform for preclinical in vivo data: learning from experience

Drug discovery today, 2017-10, Vol.22 (10), p.1539-1546

2017

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Model-based drug discovery: implementation and impact

Drug discovery today, 2013-08, Vol.18 (15-16), p.764-775

2013

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AZD3514: a small molecule that modulates androgen receptor signaling and function in vitro and in vivo

Molecular cancer therapeutics, 2013-09, Vol.12 (9), p.1715-1727

2013

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Mammalian chromodomain proteins: their role in genome organisation and expression

BioEssays, 2000-02, Vol.22 (2), p.124-137

2000

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Discovery of AZD3514, a small-molecule androgen receptor downregulator for treatment of advanced prostate cancer

Bioorganic & medicinal chemistry letters, 2013-04, Vol.23 (7), p.1945-1948

2013

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Determination of microsome and hepatocyte scaling factors for in vitro/in vivo extrapolation in the rat and dog

Xenobiotica, 2008-11, Vol.38 (11), p.1386-1398

2008

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Characterization and Chromosomal Localization of Human Hair-Specific Keratin Genes and Comparative Expression During the Hair Growth Cycle

Journal of investigative dermatology, 1998-02, Vol.110 (2), p.158-164

1998

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A New Keratin 2e Mutation in Ichthyosis Bullosa of Siemens

Journal of investigative dermatology, 1997-03, Vol.108 (3), p.354-356

1997

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Birthmark due to cutaneous mosaicism for keratin 10 mutation

The Lancet (British edition), 1995-03, Vol.345 (8949), p.596-596

1995

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Interspecies evaluation of a physiologically based pharmacokinetic model to predict the biodistribution dynamics of dendritic nanoparticles

Simulating pathways of subsurface oil in the Faroe–Shetland Channel using an ocean general circulation model

Astrocyte-mediated metaplasticity in the hippocampus: Help or hindrance?

PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: Prediction of plasma concentration–time profiles in human by using the physiologically‐based pharmacokinetic modeling approach

High resolution study of the spatial distributions of abyssal fishes by autonomous underwater vehicle

Discovery of N‑(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)‑1H‑1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors

Quantitative Evaluation of Dendritic Nanoparticles in Mice: Biodistribution Dynamics and Downstream Tumor Efficacy Outcomes

A review of the International Seabed Authority database DeepData from a biological perspective: challenges and opportunities in the UN Ocean Decade

PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 4: Prediction of plasma concentration–time profiles in human from in vivo preclinical data by using the Wajima approach

Improving the Accuracy of Predicted Human Pharmacokinetics: Lessons Learned from the AstraZeneca Drug Pipeline Over Two Decades

Comparative analysis of pattern, management and outcome of pre‐ versus postnatally diagnosed major congenital heart disease: a population‐based study

Pharmacokinetic/Pharmacodynamic Analysis of Savolitinib plus Osimertinib in an EGFR Mutation-Positive, MET-Amplified Non-Small Cell Lung Cancer Model

A PKPD Case Study: Achieving Clinically Relevant Exposures of AZD5991 in Oncology Mouse Models

Mutation of a type II keratin gene (K6a) in pachyonychia congenita

Applications of Quantitative Systems Pharmacology in Model‐Informed Drug Discovery: Perspective on Impact and Opportunities

The MET Inhibitor AZD6094 (Savolitinib, HMPL-504) Induces Regression in Papillary Renal Cell Carcinoma Patient-Derived Xenograft Models

Developing PreDICT – a fully integrated data platform for preclinical in vivo data: learning from experience

Model-based drug discovery: implementation and impact

AZD3514: a small molecule that modulates androgen receptor signaling and function in vitro and in vivo

Mammalian chromodomain proteins: their role in genome organisation and expression

Discovery of AZD3514, a small-molecule androgen receptor downregulator for treatment of advanced prostate cancer

Determination of microsome and hepatocyte scaling factors for in vitro/in vivo extrapolation in the rat and dog

Characterization and Chromosomal Localization of Human Hair-Specific Keratin Genes and Comparative Expression During the Hair Growth Cycle

A New Keratin 2e Mutation in Ichthyosis Bullosa of Siemens

Birthmark due to cutaneous mosaicism for keratin 10 mutation

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