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Embryonic stem cell-derived exosomes inhibit doxorubicin-induced TLR4-NLRP3-mediated cell death-pyroptosis

American journal of physiology. Heart and circulatory physiology, 2019-08, Vol.317 (2), p.H460-H471

2019

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SMAD-PI3K-Akt-mTOR pathway mediates BMP-7 polarization of monocytes into M2 macrophages

PloS one, 2013-12, Vol.8 (12), p.e84009

2013

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BMP-7 Treatment Increases M2 Macrophage Differentiation and Reduces Inflammation and Plaque Formation in Apo E-/- Mice

PloS one, 2016-01, Vol.11 (1), p.e0147897-e0147897

2016

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Akt—mTOR Pathway Inhibits Apoptosis and Fibrosis in Doxorubicin-Induced Cardiotoxicity following Embryonic Stem Cell Transplantation

Cell transplantation, 2015-06, Vol.24 (6), p.1031-1042

Singla, Dinender K.

2015

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MSC exosomes attenuate sterile inflammation and necroptosis associated with TAK1-pJNK-NFKB mediated cardiomyopathy in diabetic ApoE KO mice

Frontiers in immunology, 2024-02, Vol.15, p.1348043-1348043

2024

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BMP-7 Attenuates Inflammation-Induced Pyroptosis and Improves Cardiac Repair in Diabetic Cardiomyopathy

Cells (Basel, Switzerland), 2021-10, Vol.10 (10), p.2640

2021

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BMP-7 attenuates adverse cardiac remodeling mediated through M2 macrophages in prediabetic cardiomyopathy

American journal of physiology. Heart and circulatory physiology, 2014-09, Vol.307 (5), p.H762-H772

2014

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Fibroblast growth factor-9 enhances M2 macrophage differentiation and attenuates adverse cardiac remodeling in the infarcted diabetic heart

PloS one, 2015-03, Vol.10 (3), p.e0120739-e0120739

2015

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Notch-1 mediated cardiac protection following embryonic and induced pluripotent stem cell transplantation in doxorubicin-induced heart failure

PloS one, 2014-07, Vol.9 (7), p.e101024

2014

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The Role of Bone Morphogenetic Protein 7 (BMP-7) in Inflammation in Heart Diseases

Cells (Basel, Switzerland), 2020-01, Vol.9 (2), p.280

2020

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PTEN‐AKT pathway attenuates apoptosis and adverse remodeling in ponatinib‐induced skeletal muscle toxicity following BMP‐7 treatment

Physiological reports, 2023-03, Vol.11 (6), p.e15629-n/a

2023

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Stem cells and exosomes in cardiac repair

Current opinion in pharmacology, 2016-04, Vol.27, p.19-23

Singla, Dinender K

2016

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Transplanted Induced Pluripotent Stem Cells Mitigate Oxidative Stress and Improve Cardiac Function through the Akt Cell Survival Pathway in Diabetic Cardiomyopathy

Molecular pharmaceutics, 2013-09, Vol.10 (9), p.3425-3432

2013

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Induced Pluripotent Stem (iPS) Cells Repair and Regenerate Infarcted Myocardium

Molecular pharmaceutics, 2011-10, Vol.8 (5), p.1573-1581

2011

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Overexpression of TIMP-1 in Embryonic Stem Cells Attenuates Adverse Cardiac Remodeling following Myocardial Infarction

Cell transplantation, 2012-09, Vol.21 (9), p.1931-1944

2012

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Embryonic Stem Cells and Released Factors Stimulate c-kit+/FLK-1+ Progenitor Cells and Promote Neovascularization in Doxorubicin-Induced Cardiomyopathy

Cell transplantation, 2015-06, Vol.24 (6), p.1043-1052

2015

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Regulation of PTEN/Akt pathway enhances cardiomyogenesis and attenuates adverse left ventricular remodeling following thymosin β4 Overexpressing embryonic stem cell transplantation in the infarcted heart

PloS one, 2013-09, Vol.8 (9), p.e75580-e75580

2013

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Transplanted embryonic stem cells following mouse myocardial infarction inhibit apoptosis and cardiac remodeling

American journal of physiology. Heart and circulatory physiology, 2007-08, Vol.293 (2), p.H1308-H1314

2007

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Embryonic Stem Cells Improve Cardiac Function in Doxorubicin-Induced Cardiomyopathy Mediated through Multiple Mechanisms

Cell transplantation, 2012-01, Vol.21 (9), p.1919-1930

2012

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Factors released from embryonic stem cells inhibit apoptosis of H9c2 cells

American journal of physiology. Heart and circulatory physiology, 2007-09, Vol.293 (3), p.H1590-H1595

2007

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MicroRNA-1 transfected embryonic stem cells enhance cardiac myocyte differentiation and inhibit apoptosis by modulating the PTEN/Akt pathway in the infarcted heart

American journal of physiology. Heart and circulatory physiology, 2011-11, Vol.301 (5), p.H2038-H2049

2011

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PTEN inhibitor VO-OHpic attenuates inflammatory M1 macrophages and cardiac remodeling in doxorubicin-induced cardiomyopathy

American journal of physiology. Heart and circulatory physiology, 2018-11, Vol.315 (5), p.H1236-H1249

2018

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Regulation of Notch 1 signaling in THP-1 cells enhances M2 macrophage differentiation

American journal of physiology. Heart and circulatory physiology, 2014-12, Vol.307 (11), p.H1634-H1642

2014

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Exosomes derived from cardiac parasympathetic ganglionic neurons inhibit apoptosis in hyperglycemic cardiomyoblasts

Molecular and cellular biochemistry, 2019-12, Vol.462 (1-2), p.1-10

2019

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Role of phosphodiesterase 1 in the pathophysiology of diseases and potential therapeutic opportunities

Pharmacology & therapeutics (Oxford), 2021-10, Vol.226, p.107858-107858, Article 107858

2021

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Embryonic stem cell-derived exosomes inhibit doxorubicin-induced TLR4-NLRP3-mediated cell death-pyroptosis

SMAD-PI3K-Akt-mTOR pathway mediates BMP-7 polarization of monocytes into M2 macrophages

BMP-7 Treatment Increases M2 Macrophage Differentiation and Reduces Inflammation and Plaque Formation in Apo E-/- Mice

Akt—mTOR Pathway Inhibits Apoptosis and Fibrosis in Doxorubicin-Induced Cardiotoxicity following Embryonic Stem Cell Transplantation

MSC exosomes attenuate sterile inflammation and necroptosis associated with TAK1-pJNK-NFKB mediated cardiomyopathy in diabetic ApoE KO mice

BMP-7 Attenuates Inflammation-Induced Pyroptosis and Improves Cardiac Repair in Diabetic Cardiomyopathy

BMP-7 attenuates adverse cardiac remodeling mediated through M2 macrophages in prediabetic cardiomyopathy

Fibroblast growth factor-9 enhances M2 macrophage differentiation and attenuates adverse cardiac remodeling in the infarcted diabetic heart

Notch-1 mediated cardiac protection following embryonic and induced pluripotent stem cell transplantation in doxorubicin-induced heart failure

The Role of Bone Morphogenetic Protein 7 (BMP-7) in Inflammation in Heart Diseases

PTEN‐AKT pathway attenuates apoptosis and adverse remodeling in ponatinib‐induced skeletal muscle toxicity following BMP‐7 treatment

Stem cells and exosomes in cardiac repair

Transplanted Induced Pluripotent Stem Cells Mitigate Oxidative Stress and Improve Cardiac Function through the Akt Cell Survival Pathway in Diabetic Cardiomyopathy

Induced Pluripotent Stem (iPS) Cells Repair and Regenerate Infarcted Myocardium

Overexpression of TIMP-1 in Embryonic Stem Cells Attenuates Adverse Cardiac Remodeling following Myocardial Infarction

Embryonic Stem Cells and Released Factors Stimulate c-kit+/FLK-1+ Progenitor Cells and Promote Neovascularization in Doxorubicin-Induced Cardiomyopathy

Regulation of PTEN/Akt pathway enhances cardiomyogenesis and attenuates adverse left ventricular remodeling following thymosin β4 Overexpressing embryonic stem cell transplantation in the infarcted heart

Transplanted embryonic stem cells following mouse myocardial infarction inhibit apoptosis and cardiac remodeling

Embryonic Stem Cells Improve Cardiac Function in Doxorubicin-Induced Cardiomyopathy Mediated through Multiple Mechanisms

Factors released from embryonic stem cells inhibit apoptosis of H9c2 cells

MicroRNA-1 transfected embryonic stem cells enhance cardiac myocyte differentiation and inhibit apoptosis by modulating the PTEN/Akt pathway in the infarcted heart

PTEN inhibitor VO-OHpic attenuates inflammatory M1 macrophages and cardiac remodeling in doxorubicin-induced cardiomyopathy

Regulation of Notch 1 signaling in THP-1 cells enhances M2 macrophage differentiation

Exosomes derived from cardiac parasympathetic ganglionic neurons inhibit apoptosis in hyperglycemic cardiomyoblasts

Role of phosphodiesterase 1 in the pathophysiology of diseases and potential therapeutic opportunities

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