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Pharmacokinetic Interactions Between Isavuconazole and the Drug Transporter Substrates Atorvastatin, Digoxin, Metformin, and Methotrexate in Healthy Subjects

Clinical pharmacology in drug development, 2017-01, Vol.6 (1), p.66-75

2017

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Discovery of a novel neuroprotective compound, AS1219164, by high-throughput chemical screening of a newly identified apoptotic gene marker

European journal of pharmacology, 2011-11, Vol.669 (1-3), p.7-14

2011

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Real-Time Imaging of Single Retinal Cell Apoptosis in a Non-Human Primate Ocular Hypertension Model

Translational vision science & technology, 2024-01, Vol.13 (1), p.20-20

2024

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Isavuconazole absorption following oral administration in healthy subjects is comparable to intravenous dosing, and is not affected by food, or drugs that alter stomach pH

International journal of clinical pharmacology and therapeutics, 2016-08, Vol.54 (8), p.572-580

2016

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No Dose Adjustment for Isavuconazole Based on Age or Sex

Antimicrobial agents and chemotherapy, 2019-06, Vol.63 (6)

2019

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Neuroprotective efficacy of the peroxisome proliferator-activated receptor delta-selective agonists in vitro and in vivo

The Journal of pharmacology and experimental therapeutics, 2007-03, Vol.320 (3), p.1087-1096

2007

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Suppressive effects of FR167653, an inhibitor of p38 mitogen-activated kinase, on calreticulin mRNA expression induced by endoplasmic reticulum stresses

European journal of pharmacology, 2004-01, Vol.484 (2), p.147-156

2004

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Pharmacokinetic Evaluation of CYP3A4‐Mediated Drug‐Drug Interactions of Isavuconazole With Rifampin, Ketoconazole, Midazolam, and Ethinyl Estradiol/Norethindrone in Healthy Adults

Clinical pharmacology in drug development, 2017-01, Vol.6 (1), p.44-53

2017

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Pharmacokinetic Assessment of Drug‐Drug Interactions of Isavuconazole With the Immunosuppressants Cyclosporine, Mycophenolic Acid, Prednisolone, Sirolimus, and Tacrolimus in Healthy Adults

Clinical pharmacology in drug development, 2017-01, Vol.6 (1), p.76-85

2017

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AS1907417, a novel GPR119 agonist, as an insulinotropic and β-cell preservative agent for the treatment of type 2 diabetes

Biochemical and biophysical research communications, 2010-10, Vol.400 (4), p.745-751

2010

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Chronic treatment with novel GPR40 agonists improve whole-body glucose metabolism based on the glucose-dependent insulin secretion

The Journal of pharmacology and experimental therapeutics, 2013-09, Vol.346 (3), p.443-452

2013

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ASP9853, an inhibitor of inducible nitric oxide synthase dimerization, in combination with docetaxel: preclinical investigation and a Phase I study in advanced solid tumors

Cancer chemotherapy and pharmacology, 2016-03, Vol.77 (3), p.549-558

2016

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Pharmacokinetic and Pharmacodynamic Evaluation of the Drug‐Drug Interaction Between Isavuconazole and Warfarin in Healthy Subjects

Clinical pharmacology in drug development, 2017-01, Vol.6 (1), p.86-92

2017

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Pharmacokinetic Interaction Between Isavuconazole and a Fixed‐Dose Combination of Lopinavir 400 mg/Ritonavir 100 mg in Healthy Subjects

Clinical pharmacology in drug development, 2017-01, Vol.6 (1), p.93-101

2017

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Comparison of the Safety, Tolerability, and Pharmacokinetics of Fidaxomicin in Healthy Japanese and Caucasian Subjects

Clinical drug investigation, 2015-06, Vol.35 (6), p.375-384

2015

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Pharmacokinetic Effects of Isavuconazole Coadministration With the Cytochrome P450 Enzyme Substrates Bupropion, Repaglinide, Caffeine, Dextromethorphan, and Methadone in Healthy Subjects

Clinical pharmacology in drug development, 2017-01, Vol.6 (1), p.54-65

2017

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Diclofenac, a non-steroidal anti-inflammatory drug, suppresses apoptosis induced by endoplasmic reticulum stresses by inhibiting caspase signaling

Neuropharmacology, 2006-04, Vol.50 (5), p.558-567

2006

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Bacillus subtilis histone-like protein, HBsu, is an integral component of a SRP-like particle that can bind the Alu domain of small cytoplasmic RNA

The Journal of biological chemistry, 1999-05, Vol.274 (19), p.13569-13576

1999

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Detailed in vitro pharmacological analysis of FK506-induced neuroprotection

Neuropharmacology, 2003-09, Vol.45 (3), p.394-403

2003

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CyclinB2 and BIRC5 genes as surrogate biomarkers for neurite outgrowth in SH-SY5Y subclonal cells

Neuropharmacology, 2006-06, Vol.50 (8), p.1041-1047

2006

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Differences in gene expression profile among SH‐SY5Y neuroblastoma subclones with different neurite outgrowth responses to nerve growth factor

Journal of neurochemistry, 2005-09, Vol.94 (5), p.1264-1276

2005

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Protective effect of FK506 against apoptosis of SH-SY5Y cells correlates with regulation of the serum inducible kinase gene

Biochemical pharmacology, 2005-05, Vol.69 (10), p.1473-1481

2005

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Discovery of novel inhibitors of inducible nitric oxide synthase

Journal of pharmacy and pharmacology, 2002-08, Vol.54 (8), p.1141-1145

2002

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Depletion of Bacillus subtilis histone-like protein, HBsu, causes defective protein translocation and induces upregulation of small cytoplasmic RNA

Biochemical and biophysical research communications, 1999-04, Vol.258 (1), p.211-214

1999

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Synthetic Approach to Pharmacologically Active Heterocycles

YAKUGAKU ZASSHI, 1987/07/25, Vol.107(7), pp.459-470

1987

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Pharmacokinetic Interactions Between Isavuconazole and the Drug Transporter Substrates Atorvastatin, Digoxin, Metformin, and Methotrexate in Healthy Subjects

Discovery of a novel neuroprotective compound, AS1219164, by high-throughput chemical screening of a newly identified apoptotic gene marker

Real-Time Imaging of Single Retinal Cell Apoptosis in a Non-Human Primate Ocular Hypertension Model

Isavuconazole absorption following oral administration in healthy subjects is comparable to intravenous dosing, and is not affected by food, or drugs that alter stomach pH

No Dose Adjustment for Isavuconazole Based on Age or Sex

Neuroprotective efficacy of the peroxisome proliferator-activated receptor delta-selective agonists in vitro and in vivo

Suppressive effects of FR167653, an inhibitor of p38 mitogen-activated kinase, on calreticulin mRNA expression induced by endoplasmic reticulum stresses

Pharmacokinetic Evaluation of CYP3A4‐Mediated Drug‐Drug Interactions of Isavuconazole With Rifampin, Ketoconazole, Midazolam, and Ethinyl Estradiol/Norethindrone in Healthy Adults

Pharmacokinetic Assessment of Drug‐Drug Interactions of Isavuconazole With the Immunosuppressants Cyclosporine, Mycophenolic Acid, Prednisolone, Sirolimus, and Tacrolimus in Healthy Adults

AS1907417, a novel GPR119 agonist, as an insulinotropic and β-cell preservative agent for the treatment of type 2 diabetes

Chronic treatment with novel GPR40 agonists improve whole-body glucose metabolism based on the glucose-dependent insulin secretion

ASP9853, an inhibitor of inducible nitric oxide synthase dimerization, in combination with docetaxel: preclinical investigation and a Phase I study in advanced solid tumors

Pharmacokinetic and Pharmacodynamic Evaluation of the Drug‐Drug Interaction Between Isavuconazole and Warfarin in Healthy Subjects

Pharmacokinetic Interaction Between Isavuconazole and a Fixed‐Dose Combination of Lopinavir 400 mg/Ritonavir 100 mg in Healthy Subjects

Comparison of the Safety, Tolerability, and Pharmacokinetics of Fidaxomicin in Healthy Japanese and Caucasian Subjects

Pharmacokinetic Effects of Isavuconazole Coadministration With the Cytochrome P450 Enzyme Substrates Bupropion, Repaglinide, Caffeine, Dextromethorphan, and Methadone in Healthy Subjects

Diclofenac, a non-steroidal anti-inflammatory drug, suppresses apoptosis induced by endoplasmic reticulum stresses by inhibiting caspase signaling

Bacillus subtilis histone-like protein, HBsu, is an integral component of a SRP-like particle that can bind the Alu domain of small cytoplasmic RNA

Detailed in vitro pharmacological analysis of FK506-induced neuroprotection

CyclinB2 and BIRC5 genes as surrogate biomarkers for neurite outgrowth in SH-SY5Y subclonal cells

Differences in gene expression profile among SH‐SY5Y neuroblastoma subclones with different neurite outgrowth responses to nerve growth factor

Protective effect of FK506 against apoptosis of SH-SY5Y cells correlates with regulation of the serum inducible kinase gene

Discovery of novel inhibitors of inducible nitric oxide synthase

Depletion of Bacillus subtilis histone-like protein, HBsu, causes defective protein translocation and induces upregulation of small cytoplasmic RNA

Synthetic Approach to Pharmacologically Active Heterocycles

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