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Leveraging Human Plasma‐Derived Small Extracellular Vesicles as Liquid Biopsy to Study the Induction of Cytochrome P450 3A4 by Modafinil

Clinical pharmacology and therapeutics, 2022-02, Vol.111 (2), p.425-434

2022

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Dicloxacillin induces CYP2C19, CYP2C9 and CYP3A4 in vivo and in vitro

British journal of clinical pharmacology, 2018-03, Vol.84 (3), p.510-519

2018

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CYP induction-mediated drug interactions: in vitro assessment and clinical implications

Pharmaceutical research, 2006-06, Vol.23 (6), p.1089-1116

Lin, Jiunn H

2006

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Evaluation of Endogenous Metabolic Markers of Hepatic CYP3A Activity Using Metabolic Profiling and Midazolam Clearance

Clinical pharmacology and therapeutics, 2013-11, Vol.94 (5), p.601-609

2013

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Intestinal Drug Transporter Expression and the Impact of Grapefruit Juice in Humans

Clinical pharmacology and therapeutics, 2007-03, Vol.81 (3), p.362-370

2007

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Evaluation of Various Static and Dynamic Modeling Methods to Predict Clinical CYP3A Induction Using In Vitro CYP3A4 mRNA Induction Data

Clinical pharmacology and therapeutics, 2014-02, Vol.95 (2), p.179-188

2014

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Effects of atorvastatin metabolites on induction of drug‐metabolizing enzymes and membrane transporters through human pregnane X receptor

British journal of pharmacology, 2012-03, Vol.165 (5), p.1595-1608

2012

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4β‐hydroxycholesterol correlates with dose but not steady‐state concentration of carbamazepine: indication of intestinal CYP3A in biomarker formation?

British journal of clinical pharmacology, 2016-02, Vol.81 (2), p.269-276

2016

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Evaluation of Aroclor 1260 exposure in a mouse model of diet-induced obesity and non-alcoholic fatty liver disease

Toxicology and applied pharmacology, 2014-09, Vol.279 (3), p.380-390

2014

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Effect of Rifampicin on the Pharmacokinetics of Lenvatinib in Healthy Adults

Clinical drug investigation, 2014-09, Vol.34 (9), p.651-659

2014

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P-glycoprotein deficiency enhances metabolic activation of and platelet response to clopidogrel through marked up-regulation of Cyp3a11 in mice: Direct evidence for the interplay between P-glycoprotein and Cyp3a

Biochemical pharmacology, 2021-01, Vol.183, p.114313, Article 114313

2021

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Evaluation of 6β‐Hydroxycortisol, 6β‐Hydroxycortisone, and a Combination of the Two as Endogenous Probes for Inhibition of CYP3A4 In Vivo

Clinical pharmacology and therapeutics, 2011-06, Vol.89 (6), p.888-895

2011

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Bioactive Terpenoids and Flavonoids from Ginkgo Biloba Extract Induce the Expression of Hepatic Drug-Metabolizing Enzymes Through Pregnane X Receptor, Constitutive Androstane Receptor, and Aryl hydrocarbon Receptor-Mediated Pathways

Pharmaceutical research, 2009-04, Vol.26 (4), p.872-882

2009

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Impacts of Blast-Induced Traumatic Brain Injury on Expressions of Hepatic Cytochrome P450 1A2, 2B1, 2D1, and 3A2 in Rats

Cellular and molecular neurobiology, 2017-01, Vol.37 (1), p.111-120

2017

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Role of the nuclear xenobiotic receptors CAR and PXR in induction of cytochromes P450 by non-dioxinlike polychlorinated biphenyls in cultured rat hepatocytes

Toxicology and applied pharmacology, 2013-10, Vol.272 (1), p.77-85

2013

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The Effect of CYP3A4 Inhibition or Induction on the Pharmacokinetics and Pharmacodynamics of Orally Administered Ruxolitinib (INCB018424 Phosphate) in Healthy Volunteers

Journal of clinical pharmacology, 2012-06, Vol.52 (6), p.809-818

2012

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Enhancement of hepatic 4‐hydroxylation of 25‐hydroxyvitamin D3 through CYP3A4 induction in vitro and in vivo: Implications for drug‐induced osteomalacia

Journal of bone and mineral research, 2013-05, Vol.28 (5), p.1101-1116

2013

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Comparison of the induction profile for drug disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells

British journal of pharmacology, 2008-02, Vol.153 (4), p.805-819

2008

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Suppression of miR-628-3p and miR-641 is involved in rifampin-mediated CYP3A4 induction in HepaRG cells

Pharmacogenomics, 2017-01, Vol.18 (1), p.57-64

2017

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In Vitro Prediction of Clinical Drug Interactions With CYP3A Substrates: We Are Not There Yet

Clinical pharmacology and therapeutics, 2014-02, Vol.95 (2), p.133-135

Greenblatt, D J

2014

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Safety and Pharmacokinetics of Escalating Daily Doses of the Antituberculosis Drug Rifapentine in Healthy Volunteers

Clinical pharmacology and therapeutics, 2012-05, Vol.91 (5), p.881-888

2012

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The Effect of Induction of CYP3A4 by St John's Wort on Ambrisentan Plasma Pharmacokinetics in Volunteers of known CYP2C19 Genotype

Basic & clinical pharmacology & toxicology, 2015-05, Vol.116 (5), p.423-428

2015

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Nuclear receptor-mediated induction of CYP450 by antiretrovirals: functional consequences of NR1I2 (PXR) polymorphisms and differential prevalence in whites and sub-Saharan Africans

Journal of acquired immune deficiency syndromes (1999), 2010-12, Vol.55 (5), p.536-549

2010

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Induction of human cytochrome P450 3A4 by the irreversible myeloperoxidase inactivator PF-06282999 is mediated by the pregnane X receptor

Xenobiotica, 2018-07, Vol.48 (7), p.647-655

2018

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Evaluation of CYP3A4 inhibition and hepatotoxicity using DMSO-treated human hepatoma HuH-7 cells

Cell biology and toxicology, 2015-10, Vol.31 (4-5), p.221-230

2015

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Leveraging Human Plasma‐Derived Small Extracellular Vesicles as Liquid Biopsy to Study the Induction of Cytochrome P450 3A4 by Modafinil

Dicloxacillin induces CYP2C19, CYP2C9 and CYP3A4 in vivo and in vitro

CYP induction-mediated drug interactions: in vitro assessment and clinical implications

Evaluation of Endogenous Metabolic Markers of Hepatic CYP3A Activity Using Metabolic Profiling and Midazolam Clearance

Intestinal Drug Transporter Expression and the Impact of Grapefruit Juice in Humans

Evaluation of Various Static and Dynamic Modeling Methods to Predict Clinical CYP3A Induction Using In Vitro CYP3A4 mRNA Induction Data

Effects of atorvastatin metabolites on induction of drug‐metabolizing enzymes and membrane transporters through human pregnane X receptor

4β‐hydroxycholesterol correlates with dose but not steady‐state concentration of carbamazepine: indication of intestinal CYP3A in biomarker formation?

Evaluation of Aroclor 1260 exposure in a mouse model of diet-induced obesity and non-alcoholic fatty liver disease

Effect of Rifampicin on the Pharmacokinetics of Lenvatinib in Healthy Adults

P-glycoprotein deficiency enhances metabolic activation of and platelet response to clopidogrel through marked up-regulation of Cyp3a11 in mice: Direct evidence for the interplay between P-glycoprotein and Cyp3a

Evaluation of 6β‐Hydroxycortisol, 6β‐Hydroxycortisone, and a Combination of the Two as Endogenous Probes for Inhibition of CYP3A4 In Vivo

Bioactive Terpenoids and Flavonoids from Ginkgo Biloba Extract Induce the Expression of Hepatic Drug-Metabolizing Enzymes Through Pregnane X Receptor, Constitutive Androstane Receptor, and Aryl hydrocarbon Receptor-Mediated Pathways

Impacts of Blast-Induced Traumatic Brain Injury on Expressions of Hepatic Cytochrome P450 1A2, 2B1, 2D1, and 3A2 in Rats

Role of the nuclear xenobiotic receptors CAR and PXR in induction of cytochromes P450 by non-dioxinlike polychlorinated biphenyls in cultured rat hepatocytes

The Effect of CYP3A4 Inhibition or Induction on the Pharmacokinetics and Pharmacodynamics of Orally Administered Ruxolitinib (INCB018424 Phosphate) in Healthy Volunteers

Enhancement of hepatic 4‐hydroxylation of 25‐hydroxyvitamin D3 through CYP3A4 induction in vitro and in vivo: Implications for drug‐induced osteomalacia

Comparison of the induction profile for drug disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells

Suppression of miR-628-3p and miR-641 is involved in rifampin-mediated CYP3A4 induction in HepaRG cells

In Vitro Prediction of Clinical Drug Interactions With CYP3A Substrates: We Are Not There Yet

Safety and Pharmacokinetics of Escalating Daily Doses of the Antituberculosis Drug Rifapentine in Healthy Volunteers

The Effect of Induction of CYP3A4 by St John's Wort on Ambrisentan Plasma Pharmacokinetics in Volunteers of known CYP2C19 Genotype

Nuclear receptor-mediated induction of CYP450 by antiretrovirals: functional consequences of NR1I2 (PXR) polymorphisms and differential prevalence in whites and sub-Saharan Africans

Induction of human cytochrome P450 3A4 by the irreversible myeloperoxidase inactivator PF-06282999 is mediated by the pregnane X receptor

Evaluation of CYP3A4 inhibition and hepatotoxicity using DMSO-treated human hepatoma HuH-7 cells

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