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Nuclear lamins and laminopathies

The Journal of pathology, 2012-01, Vol.226 (2), p.316-325

Worman, Howard J.

2012

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Accessorizing and anchoring the LINC complex for multifunctionality

The Journal of cell biology, 2015-01, Vol.208 (1), p.11-22

2015

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Prelamin A and ZMPSTE24 in premature and physiological aging

Nucleus (Austin, Tex.), 2023-12, Vol.14 (1), p.2270345-2270345

2023

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Mitogen-Activated Protein Kinase Inhibitors Improve Heart Function and Prevent Fibrosis in Cardiomyopathy Caused by Mutation in Lamin A/C Gene

Circulation (New York, N.Y.), 2011-01, Vol.123 (1), p.53-61

2011

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Laminopathies and the long strange trip from basic cell biology to therapy

The Journal of clinical investigation, 2009-07, Vol.119 (7), p.1825-1836

2009

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ERK1/2 directly acts on CTGF/CCN2 expression to mediate myocardial fibrosis in cardiomyopathy caused by mutations in the lamin A/C gene

Human molecular genetics, 2016-06, Vol.25 (11), p.2220-2233

2016

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Temsirolimus activates autophagy and ameliorates cardiomyopathy caused by lamin A/C gene mutation

Science translational medicine, 2012-07, Vol.4 (144), p.144ra102

2012

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Ryanodine receptor remodeling in cardiomyopathy and muscular dystrophy caused by lamin A/C gene mutation

Human molecular genetics, 2020-12, Vol.29 (24), p.3919-3934

2020

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Cofilin-1 phosphorylation catalyzed by ERK1/2 alters cardiac actin dynamics in dilated cardiomyopathy caused by lamin A/C gene mutation

Human molecular genetics, 2018-09, Vol.27 (17), p.3060-3078

2018

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TorsinA controls TAN line assembly and the retrograde flow of dorsal perinuclear actin cables during rearward nuclear movement

The Journal of cell biology, 2017-03, Vol.216 (3), p.657-674

2017

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Biliary apotopes and anti‐mitochondrial antibodies activate innate immune responses in primary biliary cirrhosis

Hepatology (Baltimore, Md.), 2010-09, Vol.52 (3), p.987-998

2010

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Risk factors and comorbidities in primary biliary cirrhosis : A controlled interview-based study of 1032 patients

Hepatology (Baltimore, Md.), 2005-11, Vol.42 (5), p.1194-1202

2005

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Elevated dual specificity protein phosphatase 4 in cardiomyopathy caused by lamin A/C gene mutation is primarily ERK1/2-dependent and its depletion improves cardiac function and survival

Human molecular genetics, 2018-07, Vol.27 (13), p.2290-2305

2018

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Activation of MAPK pathways links LMNA mutations to cardiomyopathy in Emery-Dreifuss muscular dystrophy

The Journal of clinical investigation, 2007-05, Vol.117 (5), p.1282-1293

2007

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Jaundice in patients with COVID‐19

JGH open, 2021-10, Vol.5 (10), p.1166-1171

2021

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Activation of MAPK in hearts of EMD null mice: similarities between mouse models of X-linked and autosomal dominant Emery–Dreifuss muscular dystrophy

Human molecular genetics, 2007-08, Vol.16 (15), p.1884-1895

2007

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Correlation of initial autoantibody profile and clinical outcome in primary biliary cirrhosis

Hepatology (Baltimore, Md.), 2006-05, Vol.43 (5), p.1135-1144

2006

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Permanently Farnesylated Prelamin A, Progeria, and Atherosclerosis

Circulation (New York, N.Y.), 2018-07, Vol.138 (3), p.283-286

2018

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Emery-Dreifuss muscular dystrophy: focal point nuclear envelope

Current opinion in neurology, 2019-10, Vol.32 (5), p.728

2019

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Protein structural and mechanistic basis of progeroid laminopathies

The FEBS journal, 2021-05, Vol.288 (9), p.2757-2772

2021

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Epithelial cell specificity and apotope recognition by serum autoantibodies in primary biliary cirrhosis

Hepatology (Baltimore, Md.), 2011-07, Vol.54 (1), p.196-203

2011

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Decreased WNT/β-catenin signalling contributes to the pathogenesis of dilated cardiomyopathy caused by mutations in the lamin a/C gene

Human molecular genetics, 2017-01, Vol.26 (2), p.333-343

2017

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Nuclear envelope protein autoantigens in primary biliary cirrhosis

Hepatology research, 2007-10, Vol.37 (s3), p.S406-S411

Worman, Howard J.

2007

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Abnormal p38α mitogen-activated protein kinase signaling in dilated cardiomyopathy caused by lamin A/C gene mutation

Human molecular genetics, 2012-10, Vol.21 (19), p.4325-4333

2012

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Nuclear envelope-localized torsinA-LAP1 complex regulates hepatic VLDL secretion and steatosis

The Journal of clinical investigation, 2019-11, Vol.129 (11), p.4885-4900

2019

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Nuclear lamins and laminopathies

Accessorizing and anchoring the LINC complex for multifunctionality

Prelamin A and ZMPSTE24 in premature and physiological aging

Mitogen-Activated Protein Kinase Inhibitors Improve Heart Function and Prevent Fibrosis in Cardiomyopathy Caused by Mutation in Lamin A/C Gene

Laminopathies and the long strange trip from basic cell biology to therapy

ERK1/2 directly acts on CTGF/CCN2 expression to mediate myocardial fibrosis in cardiomyopathy caused by mutations in the lamin A/C gene

Temsirolimus activates autophagy and ameliorates cardiomyopathy caused by lamin A/C gene mutation

Ryanodine receptor remodeling in cardiomyopathy and muscular dystrophy caused by lamin A/C gene mutation

Cofilin-1 phosphorylation catalyzed by ERK1/2 alters cardiac actin dynamics in dilated cardiomyopathy caused by lamin A/C gene mutation

TorsinA controls TAN line assembly and the retrograde flow of dorsal perinuclear actin cables during rearward nuclear movement

Biliary apotopes and anti‐mitochondrial antibodies activate innate immune responses in primary biliary cirrhosis

Risk factors and comorbidities in primary biliary cirrhosis : A controlled interview-based study of 1032 patients

Elevated dual specificity protein phosphatase 4 in cardiomyopathy caused by lamin A/C gene mutation is primarily ERK1/2-dependent and its depletion improves cardiac function and survival

Activation of MAPK pathways links LMNA mutations to cardiomyopathy in Emery-Dreifuss muscular dystrophy

Jaundice in patients with COVID‐19

Activation of MAPK in hearts of EMD null mice: similarities between mouse models of X-linked and autosomal dominant Emery–Dreifuss muscular dystrophy

Correlation of initial autoantibody profile and clinical outcome in primary biliary cirrhosis

Permanently Farnesylated Prelamin A, Progeria, and Atherosclerosis

Emery-Dreifuss muscular dystrophy: focal point nuclear envelope

Protein structural and mechanistic basis of progeroid laminopathies

Epithelial cell specificity and apotope recognition by serum autoantibodies in primary biliary cirrhosis

Decreased WNT/β-catenin signalling contributes to the pathogenesis of dilated cardiomyopathy caused by mutations in the lamin a/C gene

Nuclear envelope protein autoantigens in primary biliary cirrhosis

Abnormal p38α mitogen-activated protein kinase signaling in dilated cardiomyopathy caused by lamin A/C gene mutation

Nuclear envelope-localized torsinA-LAP1 complex regulates hepatic VLDL secretion and steatosis

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