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Therapeutic targeting of nuclear receptors, liver X and retinoid X receptors, for Alzheimer's disease

British journal of pharmacology, 2019-09, Vol.176 (18), p.3599-3610

2019

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Proton pump inhibitor Lansoprazole is a nuclear liver X receptor agonist

Biochemical pharmacology, 2010-05, Vol.79 (9), p.1310-1316

2010

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Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models"

Science (American Association for the Advancement of Science), 2013-05, Vol.340 (6135), p.924-924

2013

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Opposing effects of Apoe/Apoa1 double deletion on amyloid-β pathology and cognitive performance in APP mice

Brain (London, England : 1878), 2015-12, Vol.138 (Pt 12), p.3699-3715

2015

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HIGH-FAT DIET AFFECTS INFLAMMATION AND INCREASES TREM2 LEVEL IN APP MICE

Alzheimer's & dementia, 2016-07, Vol.12 (7), p.P655-P655

2016

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IMPACT OF APOE POLYMORPHISMS ON AMYLOID-BETA OLIGOMERIZATION AND ASSOCIATED COGNITIVE DECLINE

Alzheimer's & dementia, 2016-07, Vol.12 (7), p.P1038-P1039

2016

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Comment on: ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models

Science (American Association for the Advancement of Science), 2013-05, Vol.340 (6135), p.924-92c

2013

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Microtubules modulate melatonin receptors involved in phase-shifting circadian activity rhythms: in vitro and in vivo evidence

Journal of pineal research, 2009-03, Vol.46 (2), p.161-171

2009

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snoRNAs in plasma extracellular vesicles of AD patients are differentially associated with APOE genotype

Alzheimer's & dementia, 2021-12, Vol.17 (S4), p.n/a

2021

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Neural responses to peripheral infection in Alzheimer’s disease model mice

Alzheimer's & dementia, 2023-12, Vol.19 (S13)

2023

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Sex‐specific decoupling of cerebral blood flow and glucose metabolism in Alzheimer’s disease mouse model

Alzheimer's & dementia, 2022-12, Vol.18 (S6), p.n/a

2022

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Sex‐specific cerebral blood flow trajectories in mouse models of Alzheimer’s disease

Alzheimer's & dementia, 2021-12, Vol.17 (S4), p.n/a

2021

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Role of TREM2 deficiency in Alzheimer’s disease model mice expressing human APOE3 or APOE4

Alzheimer's & dementia, 2020-12, Vol.16, p.n/a

2020

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Role of TREM2 deficiency in Alzheimer’s disease model mice expressing human APOE3 or APOE4: Molecular and cell biology/neuroinflammation

Alzheimer's & dementia, 2020-12, Vol.16 (S2)

2020

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Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models"

Science (American Association for the Advancement of Science), 2013-05, Vol.340 (6135), p.924-924

2013

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LACK OF TREM2 AFFECTS THE PHENOTYPE AND TRANSCRIPTOME IN MICE EXPRESSING HUMAN APOE3 AND APOE4

Alzheimer's & dementia, 2019-07, Vol.15 (7), p.P656-P657

2019

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P2‐208: LACK OF TREM2 AFFECTS THE PHENOTYPE AND TRANSCRIPTOME IN MICE EXPRESSING HUMAN APOE3 AND APOE4

Alzheimer's & dementia, 2019-07, Vol.15 (7S_Part_12), p.P656-P657

2019

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P4‐051: EFFECT OF APOE ISOFORM ON MICROGLIAL RESPONSE TO AMYLOID‐BETA

Alzheimer's & dementia, 2018-07, Vol.14 (7S_Part_27), p.P1453-P1453

2018

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SINGLE-CELL TRANSCRIPTOMIC PROFILING OF TREM2 DEFICIENT MICROGLIA IN RESPONSE TO INTRACRANIAL INFUSION OF Aβ PARTICLES

Alzheimer's & dementia, 2019-07, Vol.15 (7), p.P610-P610

2019

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P2‐100: SINGLE‐CELL TRANSCRIPTOMIC PROFILING OF TREM2 DEFICIENT MICROGLIA IN RESPONSE TO INTRACRANIAL INFUSION OF Aβ PARTICLES

Alzheimer's & dementia, 2019-07, Vol.15 (7S_Part_11), p.P610-P610

2019

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SHOTGUN LIPIDOMICS AND RNA-SEQ REVEAL EXTENSIVE CHANGES IN CARDIOLIPIN AND PHOSPHOLIPID PATHWAYS IN BRAINS OF APOEε3/3, APOEε3/4 AND APOEε4/4 ALZHEIMER'S DISEASE PATIENTS

Alzheimer's & dementia, 2017-07, Vol.13 (7), p.P302-P302

2017

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Comment on "ApoE-Directed Therapeutics Rapidly Clear [beta]-Amyloid and Reverse Deficits in AD Mouse Models"

Science (American Association for the Advancement of Science), 2013-05, Vol.340 (6135), p.924

2013

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THE DYNAMIC CHANGES OF MICROGLIAL TRANSCRIPTOME ASSOCIATED WITH AGE AND AMYLOID PATHOLOGY

Alzheimer's & dementia, 2017-07, Vol.13 (7), p.P655-P655

2017

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P4‐253: MULTI‐OMICS PROFILING IDENTIFIES APOE‐ALLELE‐ASSOCIATED LIPID AND GENE EXPRESSION PATTERNS IN ALZHEIMER'S DISEASE

Alzheimer's & dementia, 2018-07, Vol.14 (7S_Part_29), p.P1543-P1543

2018

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P2‐113: High‐Fat Diet Affects Inflammation and Increases TREM2 Level in App Mice

Alzheimer's & dementia, 2016-07, Vol.12 (7S_Part_13), p.P655-P655

2016

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Therapeutic targeting of nuclear receptors, liver X and retinoid X receptors, for Alzheimer's disease

Proton pump inhibitor Lansoprazole is a nuclear liver X receptor agonist

Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models"

Opposing effects of Apoe/Apoa1 double deletion on amyloid-β pathology and cognitive performance in APP mice

HIGH-FAT DIET AFFECTS INFLAMMATION AND INCREASES TREM2 LEVEL IN APP MICE

IMPACT OF APOE POLYMORPHISMS ON AMYLOID-BETA OLIGOMERIZATION AND ASSOCIATED COGNITIVE DECLINE

Comment on: ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models

Microtubules modulate melatonin receptors involved in phase-shifting circadian activity rhythms: in vitro and in vivo evidence

snoRNAs in plasma extracellular vesicles of AD patients are differentially associated with APOE genotype

Neural responses to peripheral infection in Alzheimer’s disease model mice

Sex‐specific decoupling of cerebral blood flow and glucose metabolism in Alzheimer’s disease mouse model

Sex‐specific cerebral blood flow trajectories in mouse models of Alzheimer’s disease

Role of TREM2 deficiency in Alzheimer’s disease model mice expressing human APOE3 or APOE4

Role of TREM2 deficiency in Alzheimer’s disease model mice expressing human APOE3 or APOE4: Molecular and cell biology/neuroinflammation

Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models"

LACK OF TREM2 AFFECTS THE PHENOTYPE AND TRANSCRIPTOME IN MICE EXPRESSING HUMAN APOE3 AND APOE4

P2‐208: LACK OF TREM2 AFFECTS THE PHENOTYPE AND TRANSCRIPTOME IN MICE EXPRESSING HUMAN APOE3 AND APOE4

P4‐051: EFFECT OF APOE ISOFORM ON MICROGLIAL RESPONSE TO AMYLOID‐BETA

SINGLE-CELL TRANSCRIPTOMIC PROFILING OF TREM2 DEFICIENT MICROGLIA IN RESPONSE TO INTRACRANIAL INFUSION OF Aβ PARTICLES

P2‐100: SINGLE‐CELL TRANSCRIPTOMIC PROFILING OF TREM2 DEFICIENT MICROGLIA IN RESPONSE TO INTRACRANIAL INFUSION OF Aβ PARTICLES

SHOTGUN LIPIDOMICS AND RNA-SEQ REVEAL EXTENSIVE CHANGES IN CARDIOLIPIN AND PHOSPHOLIPID PATHWAYS IN BRAINS OF APOEε3/3, APOEε3/4 AND APOEε4/4 ALZHEIMER'S DISEASE PATIENTS

Comment on "ApoE-Directed Therapeutics Rapidly Clear [beta]-Amyloid and Reverse Deficits in AD Mouse Models"

THE DYNAMIC CHANGES OF MICROGLIAL TRANSCRIPTOME ASSOCIATED WITH AGE AND AMYLOID PATHOLOGY

P4‐253: MULTI‐OMICS PROFILING IDENTIFIES APOE‐ALLELE‐ASSOCIATED LIPID AND GENE EXPRESSION PATTERNS IN ALZHEIMER'S DISEASE

P2‐113: High‐Fat Diet Affects Inflammation and Increases TREM2 Level in App Mice

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