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The NLRP3 inflammasome inhibitor OLT1177 rescues cognitive impairment in a mouse model of Alzheimer’s disease

Proceedings of the National Academy of Sciences - PNAS, 2020-12, Vol.117 (50), p.32145-32154

2020

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Early IL-1 receptor blockade in severe inflammatory respiratory failure complicating COVID-19

Proceedings of the National Academy of Sciences - PNAS, 2020-08, Vol.117 (32), p.18951-18953

2020

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Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses

Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (7), p.2650-2655

2014

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Suppression of antigen-specific adaptive immunity by IL-37 via induction of tolerogenic dendritic cells

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (42), p.15178-15183

2014

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Interleukin 37 expression protects mice from colitis

Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (40), p.16711-16716

2011

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IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation

Proceedings of the National Academy of Sciences - PNAS, 2009-04, Vol.106 (17), p.7119-7124

2009

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IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans

Proceedings of the National Academy of Sciences - PNAS, 2014-03, Vol.111 (9), p.3526-3531

2014

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IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (8), p.3001-3005

2012

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Differential release of chromatin-bound IL-1α discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation

Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (6), p.2574-2579

2010

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Sterile inflammation of endothelial cell-derived apoptotic bodies is mediated by interleukin-1α

Proceedings of the National Academy of Sciences - PNAS, 2011-12, Vol.108 (51), p.20684-20689

2011

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Anti-inflammatory and immunomodulatory properties of α1-antitrypsin without inhibition of elastase

Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (37), p.15007-15012

2013

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Beneficial effects of IL-37 after spinal cord injury in mice

Proceedings of the National Academy of Sciences - PNAS, 2016-02, Vol.113 (5), p.1411-1416

2016

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NLRP1 haplotypes associated with vitiligo and autoimmunity increase interleukin-1β processing via the NLRP1 inflammasome

Proceedings of the National Academy of Sciences - PNAS, 2013-02, Vol.110 (8), p.2952-2956

2013

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MHC class II super-enhancer increases surface expression of HLA-DR and HLA-DQ and affects cytokine production in autoimmune vitiligo

Proceedings of the National Academy of Sciences - PNAS, 2016-02, Vol.113 (5), p.1363-1368

2016

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Alpha-1-antitrypsin monotherapy reduces graft-versus-host disease after experimental allogeneic bone marrow transplantation

Proceedings of the National Academy of Sciences - PNAS, 2012-01, Vol.109 (2), p.564-569

2012

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Reactive oxygen species-independent activation of the IL-1β inflammasome in cells from patients with chronic granulomatous disease

Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (7), p.3030-3033

2010

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Autoimmune vitiligo is associated with gain-of-function by a transcriptional regulator that elevates expression of HLA-A02:01 in vivo

Proceedings of the National Academy of Sciences - PNAS, 2016-02, Vol.113 (5), p.1357-1362

2016

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Interleukin-18 and Host Defense against Infection

The Journal of infectious diseases, 2003-06, Vol.187 (Supplement-2), p.S370-84

2003

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IL-1 Is Required for Tumor Invasiveness and Angiogenesis

Proceedings of the National Academy of Sciences - PNAS, 2003-03, Vol.100 (5), p.2645-2650

2003

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IL-32-dependent effects of IL-1β on endothelial cell functions

Proceedings of the National Academy of Sciences - PNAS, 2009-03, Vol.106 (10), p.3883-3888

2009

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Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection

Proceedings of the National Academy of Sciences - PNAS, 2014-01, Vol.111 (3), p.1055-1059

2014

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IL-32 Synergizes with Nucleotide Oligomerization Domain (NOD) 1 and NOD2 Ligands for IL-1β and IL-6 Production through a Caspase 1-Dependent Mechanism

Proceedings of the National Academy of Sciences - PNAS, 2005-11, Vol.102 (45), p.16309-16314

2005

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Interleukin-32 induces the differentiation of monocytes into macrophage-like cells

Proceedings of the National Academy of Sciences - PNAS, 2008-03, Vol.105 (9), p.3515-3520

2008

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Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function

Proceedings of the National Academy of Sciences - PNAS, 2008-02, Vol.105 (8), p.2865-2870

2008

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Paradoxical effects of constitutive human IL-32γ in transgenic mice during experimental colitis

Proceedings of the National Academy of Sciences - PNAS, 2010-12, Vol.107 (49), p.21082-21086

2010

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The NLRP3 inflammasome inhibitor OLT1177 rescues cognitive impairment in a mouse model of Alzheimer’s disease

Early IL-1 receptor blockade in severe inflammatory respiratory failure complicating COVID-19

Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses

Suppression of antigen-specific adaptive immunity by IL-37 via induction of tolerogenic dendritic cells

Interleukin 37 expression protects mice from colitis

IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation

IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans

IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist

Differential release of chromatin-bound IL-1α discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation

Sterile inflammation of endothelial cell-derived apoptotic bodies is mediated by interleukin-1α

Anti-inflammatory and immunomodulatory properties of α1-antitrypsin without inhibition of elastase

Beneficial effects of IL-37 after spinal cord injury in mice

NLRP1 haplotypes associated with vitiligo and autoimmunity increase interleukin-1β processing via the NLRP1 inflammasome

MHC class II super-enhancer increases surface expression of HLA-DR and HLA-DQ and affects cytokine production in autoimmune vitiligo

Alpha-1-antitrypsin monotherapy reduces graft-versus-host disease after experimental allogeneic bone marrow transplantation

Reactive oxygen species-independent activation of the IL-1β inflammasome in cells from patients with chronic granulomatous disease

Autoimmune vitiligo is associated with gain-of-function by a transcriptional regulator that elevates expression of HLA-A02:01 in vivo

Interleukin-18 and Host Defense against Infection

IL-1 Is Required for Tumor Invasiveness and Angiogenesis

IL-32-dependent effects of IL-1β on endothelial cell functions

Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection

IL-32 Synergizes with Nucleotide Oligomerization Domain (NOD) 1 and NOD2 Ligands for IL-1β and IL-6 Production through a Caspase 1-Dependent Mechanism

Interleukin-32 induces the differentiation of monocytes into macrophage-like cells

Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function

Paradoxical effects of constitutive human IL-32γ in transgenic mice during experimental colitis

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