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CACNA1S haploinsufficiency confers resistance to New World arenavirus infection

Proceedings of the National Academy of Sciences - PNAS, 2020-08, Vol.117 (32), p.19497-19506

2020

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Primary and secondary motoneurons use different calcium channel types to control escape and swimming behaviors in zebrafish

Proceedings of the National Academy of Sciences - PNAS, 2020-10, Vol.117 (42), p.26429-26437

2020

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Engineering selectivity into RGK GTPase inhibition of voltage-dependent calcium channels

Proceedings of the National Academy of Sciences - PNAS, 2018-11, Vol.115 (47), p.12051-12056

2018

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T-type calcium channels contribute to colonic hypersensitivity in a rat model of irritable bowel syndrome

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (27), p.11268-11273

2011

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The functionally relevant site for paxilline inhibition of BK channels

Proceedings of the National Academy of Sciences - PNAS, 2020-01, Vol.117 (2), p.1021-1026

2020

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Structural basis for the gating mechanism of the type 2 ryanodine receptor RyR2

Science (American Association for the Advancement of Science), 2016-10, Vol.354 (6310), p.301-301

2016

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Kv2.1 channels play opposing roles in regulating membrane potential, Ca2+ channel function, and myogenic tone in arterial smooth muscle

Proceedings of the National Academy of Sciences - PNAS, 2020-02, Vol.117 (7), p.3858-3866

2020

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Photopharmacological modulation of native CRAC channels using azoboronate photoswitches

Proceedings of the National Academy of Sciences - PNAS, 2022-03, Vol.119 (13), p.e2118160119-e2118160119

2022

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Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures

Science (American Association for the Advancement of Science), 2018-05, Vol.360 (6388), p.508-513

2018

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Cryo-EM structure of a mitochondrial calcium uniporter

Science (American Association for the Advancement of Science), 2018-08, Vol.361 (6401), p.506-511

2018

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BKCa-Cav Channel Complexes Mediate Rapid and Localized Ca²⁺-Activated K⁺ Signaling

Science (American Association for the Advancement of Science), 2006-10, Vol.314 (5799), p.615-620

2006

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Quantitative proteomics of the Cav2 channel nano-environments in the mammalian brain

Proceedings of the National Academy of Sciences - PNAS, 2010-08, Vol.107 (34), p.14950-14957

2010

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Molecular basis for allosteric regulation of the type 2 ryanodine receptor channel gating by key modulators

Proceedings of the National Academy of Sciences - PNAS, 2019-12, Vol.116 (51), p.25575-25582

2019

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Aberrant DJ-1 expression underlies L-type calcium channel hypoactivity in dendrites in tuberous sclerosis complex and Alzheimer's disease

Proceedings of the National Academy of Sciences - PNAS, 2023-11, Vol.120 (45), p.e2301534120-e2301534120

2023

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Calcium channel blockers potentiate gemcitabine chemotherapy in pancreatic cancer

Proceedings of the National Academy of Sciences - PNAS, 2022-05, Vol.119 (18), p.e2200143119-e2200143119

2022

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Functional determination of calcium-binding sites required for the activation of inositol 1,4,5-trisphosphate receptors

Proceedings of the National Academy of Sciences - PNAS, 2022-09, Vol.119 (39), p.e2209267119

2022

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Structural insights into binding of STAC proteins to voltage-gated calcium channels

Proceedings of the National Academy of Sciences - PNAS, 2017-11, Vol.114 (45), p.E9520-E9528

2017

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Structures of the junctophilin/voltage-gated calcium channel interface reveal hot spot for cardiomyopathy mutations

Proceedings of the National Academy of Sciences - PNAS, 2022-03, Vol.119 (10), p.e2120416119-e2120416119

2022

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Selectivity filter ion binding affinity determines inactivation in a potassium channel

Proceedings of the National Academy of Sciences - PNAS, 2020-11, Vol.117 (47), p.29968-29978

2020

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A pharmacological master key mechanism that unlocks the selectivity filter gate in K + channels

Science (American Association for the Advancement of Science), 2019-02, Vol.363 (6429), p.875-880

2019

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An essential role for cardiolipin in the stability and function of the mitochondrial calcium uniporter

Proceedings of the National Academy of Sciences - PNAS, 2020-07, Vol.117 (28), p.16383-16390

2020

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Structure of the human TRPM4 ion channel in a lipid nanodisc

Science (American Association for the Advancement of Science), 2018-01, Vol.359 (6372), p.228-232

2018

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Nanoscale remodeling of ryanodine receptor cluster size underlies cerebral microvascular dysfunction in Duchenne muscular dystrophy

Proceedings of the National Academy of Sciences - PNAS, 2018-10, Vol.115 (41), p.E9745-E9752

2018

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Regulation of neuronal excitation–transcription coupling by Kv2.1-induced clustering of somatic L-type Ca2+ channels at ER-PM junctions

Proceedings of the National Academy of Sciences - PNAS, 2021-11, Vol.118 (46), p.1

2021

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Distinct gating mechanism of SOC channel involving STIM–Orai coupling and an intramolecular interaction of Orai in Caenorhabditis elegans

Proceedings of the National Academy of Sciences - PNAS, 2018-05, Vol.115 (20), p.E4623-E4632

2018

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CACNA1S haploinsufficiency confers resistance to New World arenavirus infection

Primary and secondary motoneurons use different calcium channel types to control escape and swimming behaviors in zebrafish

Engineering selectivity into RGK GTPase inhibition of voltage-dependent calcium channels

T-type calcium channels contribute to colonic hypersensitivity in a rat model of irritable bowel syndrome

The functionally relevant site for paxilline inhibition of BK channels

Structural basis for the gating mechanism of the type 2 ryanodine receptor RyR2

Kv2.1 channels play opposing roles in regulating membrane potential, Ca2+ channel function, and myogenic tone in arterial smooth muscle

Photopharmacological modulation of native CRAC channels using azoboronate photoswitches

Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures

Cryo-EM structure of a mitochondrial calcium uniporter

BKCa-Cav Channel Complexes Mediate Rapid and Localized Ca²⁺-Activated K⁺ Signaling

Quantitative proteomics of the Cav2 channel nano-environments in the mammalian brain

Molecular basis for allosteric regulation of the type 2 ryanodine receptor channel gating by key modulators

Aberrant DJ-1 expression underlies L-type calcium channel hypoactivity in dendrites in tuberous sclerosis complex and Alzheimer's disease

Calcium channel blockers potentiate gemcitabine chemotherapy in pancreatic cancer

Functional determination of calcium-binding sites required for the activation of inositol 1,4,5-trisphosphate receptors

Structural insights into binding of STAC proteins to voltage-gated calcium channels

Structures of the junctophilin/voltage-gated calcium channel interface reveal hot spot for cardiomyopathy mutations

Selectivity filter ion binding affinity determines inactivation in a potassium channel

A pharmacological master key mechanism that unlocks the selectivity filter gate in K + channels

An essential role for cardiolipin in the stability and function of the mitochondrial calcium uniporter

Structure of the human TRPM4 ion channel in a lipid nanodisc

Nanoscale remodeling of ryanodine receptor cluster size underlies cerebral microvascular dysfunction in Duchenne muscular dystrophy

Regulation of neuronal excitation–transcription coupling by Kv2.1-induced clustering of somatic L-type Ca2+ channels at ER-PM junctions

Distinct gating mechanism of SOC channel involving STIM–Orai coupling and an intramolecular interaction of Orai in Caenorhabditis elegans

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