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NCC regulation by WNK signal cascade

Frontiers in physiology, 2023-01, Vol.13, p.1081261-1081261

2023

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Circulating Extracellular Vesicle-Propagated microRNA Signature as a Vascular Calcification Factor in Chronic Kidney Disease

Circulation research, 2023-02, Vol.132 (4), p.415-431

2023

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Tolvaptan activates the Nrf2/HO-1 antioxidant pathway through PERK phosphorylation

Scientific reports, 2019-06, Vol.9 (1), p.9245-10, Article 9245

2019

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Vasopressin Induces Urinary Uromodulin Secretion By Activating PKA (Protein Kinase A)

Hypertension (Dallas, Tex. 1979), 2021-06, Vol.77 (6), p.1953-1963

2021

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Burden of kidney disease on the discrepancy between reasons for hospital admission and death: An observational cohort study

PloS one, 2021-11, Vol.16 (11), p.e0258846-e0258846

2021

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Loop diuretics are associated with greater risk of sarcopenia in patients with non-dialysis-dependent chronic kidney disease

PloS one, 2018-02, Vol.13 (2), p.e0192990-e0192990

2018

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Effects of diuretics on sodium-dependent glucose cotransporter 2 inhibitor-induced changes in blood pressure in obese rats suffering from the metabolic syndrome

Journal of hypertension, 2016-05, Vol.34 (5), p.893-906

2016

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WNK4 is indispensable for the pathogenesis of pseudohypoaldosteronism type II caused by mutant KLHL3

Biochemical and biophysical research communications, 2017-09, Vol.491 (3), p.727-732

2017

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Impaired KLHL3-Mediated Ubiquitination of WNK4 Causes Human Hypertension

Cell reports (Cambridge), 2013-03, Vol.3 (3), p.858-868

2013

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The proteasome inhibitor bortezomib attenuates renal fibrosis in mice via the suppression of TGF-β1

Scientific reports, 2017-10, Vol.7 (1), p.13086-9, Article 13086

2017

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Impaired degradation of WNK1 and WNK4 kinases causes PHAII in mutant KLHL3 knock-in mice

Human molecular genetics, 2014-10, Vol.23 (19), p.5052-5060

2014

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Prognosis of chronic kidney disease with normal-range proteinuria: The CKD-ROUTE study

PloS one, 2018-01, Vol.13 (1), p.e0190493-e0190493

2018

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Phosphatidylinositol 3-Kinase/Akt Signaling Pathway Activates the WNK-OSR1/SPAK-NCC Phosphorylation Cascade in Hyperinsulinemic db/db Mice

Hypertension (Dallas, Tex. 1979), 2012-10, Vol.60 (4), p.981-990

2012

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Impact of COVID-19 versus other pneumonia on in-hospital mortality and functional decline among Japanese dialysis patients: a retrospective cohort study

Scientific reports, 2024-03, Vol.14 (1), p.5177-5177, Article 5177

2024

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Molecular pathogenesis of pseudohypoaldosteronism type II: generation and analysis of a Wnk4(D561A/+) knockin mouse model

Cell metabolism, 2007-05, Vol.5 (5), p.331-344

2007

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WNK1 regulates skeletal muscle cell hypertrophy by modulating the nuclear localization and transcriptional activity of FOXO4

Scientific reports, 2018-06, Vol.8 (1), p.9101-12, Article 9101

2018

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Sodium–calcium exchanger 1 is the key molecule for urinary potassium excretion against acute hyperkalemia

PloS one, 2020-06, Vol.15 (6), p.e0235360-e0235360

2020

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Copy Number Variation: A New Genetic Form of Polycystic Kidney and Liver Disease

Kidney international reports, 2020-05, Vol.5 (5), p.575-576

2020

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Loop diuretics affect skeletal myoblast differentiation and exercise-induced muscle hypertrophy

Scientific reports, 2017-04, Vol.7 (1), p.46369-46369, Article 46369

2017

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Immunolocalization and translocation of aquaporin-5 water channel in sweat glands

Journal of dermatological science, 2013-04, Vol.70 (1), p.26-33

2013

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Dietary Salt Intake Regulates WNK3–SPAK–NKCC1 Phosphorylation Cascade in Mouse Aorta Through Angiotensin II

Hypertension (Dallas, Tex. 1979), 2013-11, Vol.62 (5), p.872-878

2013

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Acute insulin stimulation induces phosphorylation of the Na-Cl cotransporter in cultured distal mpkDCT cells and mouse kidney

PloS one, 2011-08, Vol.6 (8), p.e24277-e24277

2011

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Nationwide in-hospital mortality following major fractures among hemodialysis patients and the general population: An observational cohort study

Bone (New York, N.Y.), 2020-01, Vol.130, p.115122-115122, Article 115122

2020

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WNK3 kinase maintains neuronal excitability by reducing inwardly rectifying K+ conductance in layer V pyramidal neurons of mouse medial prefrontal cortex

Frontiers in molecular neuroscience, 2022-10, Vol.15, p.856262-856262

2022

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Metformin increases urinary sodium excretion by reducing phosphorylation of the sodium-chloride cotransporter

Metabolism, clinical and experimental, 2018-08, Vol.85, p.23-31

2018

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NCC regulation by WNK signal cascade

Circulating Extracellular Vesicle-Propagated microRNA Signature as a Vascular Calcification Factor in Chronic Kidney Disease

Tolvaptan activates the Nrf2/HO-1 antioxidant pathway through PERK phosphorylation

Vasopressin Induces Urinary Uromodulin Secretion By Activating PKA (Protein Kinase A)

Burden of kidney disease on the discrepancy between reasons for hospital admission and death: An observational cohort study

Loop diuretics are associated with greater risk of sarcopenia in patients with non-dialysis-dependent chronic kidney disease

Effects of diuretics on sodium-dependent glucose cotransporter 2 inhibitor-induced changes in blood pressure in obese rats suffering from the metabolic syndrome

WNK4 is indispensable for the pathogenesis of pseudohypoaldosteronism type II caused by mutant KLHL3

Impaired KLHL3-Mediated Ubiquitination of WNK4 Causes Human Hypertension

The proteasome inhibitor bortezomib attenuates renal fibrosis in mice via the suppression of TGF-β1

Impaired degradation of WNK1 and WNK4 kinases causes PHAII in mutant KLHL3 knock-in mice

Prognosis of chronic kidney disease with normal-range proteinuria: The CKD-ROUTE study

Phosphatidylinositol 3-Kinase/Akt Signaling Pathway Activates the WNK-OSR1/SPAK-NCC Phosphorylation Cascade in Hyperinsulinemic db/db Mice

Impact of COVID-19 versus other pneumonia on in-hospital mortality and functional decline among Japanese dialysis patients: a retrospective cohort study

Molecular pathogenesis of pseudohypoaldosteronism type II: generation and analysis of a Wnk4(D561A/+) knockin mouse model

WNK1 regulates skeletal muscle cell hypertrophy by modulating the nuclear localization and transcriptional activity of FOXO4

Sodium–calcium exchanger 1 is the key molecule for urinary potassium excretion against acute hyperkalemia

Copy Number Variation: A New Genetic Form of Polycystic Kidney and Liver Disease

Loop diuretics affect skeletal myoblast differentiation and exercise-induced muscle hypertrophy

Immunolocalization and translocation of aquaporin-5 water channel in sweat glands

Dietary Salt Intake Regulates WNK3–SPAK–NKCC1 Phosphorylation Cascade in Mouse Aorta Through Angiotensin II

Acute insulin stimulation induces phosphorylation of the Na-Cl cotransporter in cultured distal mpkDCT cells and mouse kidney

Nationwide in-hospital mortality following major fractures among hemodialysis patients and the general population: An observational cohort study

WNK3 kinase maintains neuronal excitability by reducing inwardly rectifying K+ conductance in layer V pyramidal neurons of mouse medial prefrontal cortex

Metformin increases urinary sodium excretion by reducing phosphorylation of the sodium-chloride cotransporter

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