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Methods Favoring Homology-Directed Repair Choice in Response to CRISPR/Cas9 Induced-Double Strand Breaks

International journal of molecular sciences, 2020-09, Vol.21 (18), p.6461

2020

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DNA Repair in Prostate Cancer: Biology and Clinical Implications

European urology, 2017-03, Vol.71 (3), p.417-425

2017

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Homology and enzymatic requirements of microhomology-dependent alternative end joining

Cell death & disease, 2015-03, Vol.6 (3), p.e1697-e1697

2015

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Lingering single-strand breaks trigger Rad51-independent homology-directed repair of collapsed replication forks in the polynucleotide kinase/phosphatase mutant of fission yeast

PLoS genetics, 2017-09, Vol.13 (9), p.e1007013-e1007013

2017

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PAXX Is an Accessory c-NHEJ Factor that Associates with Ku70 and Has Overlapping Functions with XLF

Cell reports (Cambridge), 2016-10, Vol.17 (2), p.541-555

2016

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Mutations in PNKP cause microcephaly, seizures and defects in DNA repair

Nature genetics, 2010-03, Vol.42 (3), p.245-249

2010

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Nuclear Dynamics of Heterochromatin Repair

Trends in genetics, 2017-02, Vol.33 (2), p.86-100

2017

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DNA-repair defects in pancreatic neuroendocrine tumors and potential clinical applications

Cancer treatment reviews, 2016-03, Vol.44, p.1-9

2016

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Limiting DNA polymerase delta alters replication dynamics and leads to a dependence on checkpoint activation and recombination-mediated DNA repair

PLoS genetics, 2021-01, Vol.17 (1), p.e1009322-e1009322

2021

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Genetic interaction between DNA repair factors PAXX, XLF, XRCC4 and DNA‐PKcs in human cells

FEBS open bio, 2019-07, Vol.9 (7), p.1315-1326

2019

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Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Nature, 2008-10, Vol.455 (7216), p.1061-1068

2008

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Is non-homologous end-joining really an inherently error-prone process?

PLoS genetics, 2014-01, Vol.10 (1), p.e1004086-e1004086

2014

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Meiotic Cas9 expression mediates gene conversion in the male and female mouse germline

PLoS biology, 2021-12, Vol.19 (12), p.e3001478-e3001478

2021

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Genome-wide sequencing analysis of Sgs1, Exo1, Rad51, and Srs2 in DNA repair by homologous recombination

Cell reports (Cambridge), 2022-01, Vol.38 (2), p.110201-110201, Article 110201

2022

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Depletion of Akt1 and Akt2 Impairs the Repair of Radiation-Induced DNA Double Strand Breaks via Homologous Recombination

International journal of molecular sciences, 2019-12, Vol.20 (24), p.6316

2019

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Rad51 filaments assembled in the absence of the complex formed by the Rad51 paralogs Rad55 and Rad57 are outcompeted by translesion DNA polymerases on UV-induced ssDNA gaps

PLoS genetics, 2023-02, Vol.19 (2), p.e1010639-e1010639

2023

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Double-strand break repair processes drive evolution of the mitochondrial genome in Arabidopsis

BMC biology, 2011-09, Vol.9 (1), p.64-64, Article 64

2011

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Colon and Endometrial Cancers With Mismatch Repair Deficiency Can Arise From Somatic, Rather Than Germline, Mutations

Gastroenterology (New York, N.Y. 1943), 2014-12, Vol.147 (6), p.1308-1316.e1

2014

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Functional analysis of BARD1 missense variants in homology-directed repair and damage sensitivity

PLoS genetics, 2019-03, Vol.15 (3), p.e1008049-e1008049

2019

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Mek1 Down Regulates Rad51 Activity during Yeast Meiosis by Phosphorylation of Hed1

PLoS genetics, 2016-08, Vol.12 (8), p.e1006226-e1006226

2016

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Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks

PLoS genetics, 2011-09, Vol.7 (9), p.e1002271-e1002271

2011

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CSB-PGBD3 Mutations Cause Premature Ovarian Failure

PLoS genetics, 2015-07, Vol.11 (7), p.e1005419-e1005419

2015

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The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3'-phosphatase in spinocerebellar ataxia type 3 pathogenesis

PLoS genetics, 2015-01, Vol.11 (1), p.e1004749

2015

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A Rad51-independent pathway promotes single-strand template repair in gene editing

PLoS genetics, 2020-10, Vol.16 (10), p.e1008689-e1008689

2020

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DNA damage response factors from diverse pathways, including DNA crosslink repair, mediate alternative end joining

PLoS genetics, 2015-01, Vol.11 (1), p.e1004943-e1004943

2015

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Methods Favoring Homology-Directed Repair Choice in Response to CRISPR/Cas9 Induced-Double Strand Breaks

DNA Repair in Prostate Cancer: Biology and Clinical Implications

Homology and enzymatic requirements of microhomology-dependent alternative end joining

Lingering single-strand breaks trigger Rad51-independent homology-directed repair of collapsed replication forks in the polynucleotide kinase/phosphatase mutant of fission yeast

PAXX Is an Accessory c-NHEJ Factor that Associates with Ku70 and Has Overlapping Functions with XLF

Mutations in PNKP cause microcephaly, seizures and defects in DNA repair

Nuclear Dynamics of Heterochromatin Repair

DNA-repair defects in pancreatic neuroendocrine tumors and potential clinical applications

Limiting DNA polymerase delta alters replication dynamics and leads to a dependence on checkpoint activation and recombination-mediated DNA repair

Genetic interaction between DNA repair factors PAXX, XLF, XRCC4 and DNA‐PKcs in human cells

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Is non-homologous end-joining really an inherently error-prone process?

Meiotic Cas9 expression mediates gene conversion in the male and female mouse germline

Genome-wide sequencing analysis of Sgs1, Exo1, Rad51, and Srs2 in DNA repair by homologous recombination

Depletion of Akt1 and Akt2 Impairs the Repair of Radiation-Induced DNA Double Strand Breaks via Homologous Recombination

Rad51 filaments assembled in the absence of the complex formed by the Rad51 paralogs Rad55 and Rad57 are outcompeted by translesion DNA polymerases on UV-induced ssDNA gaps

Double-strand break repair processes drive evolution of the mitochondrial genome in Arabidopsis

Colon and Endometrial Cancers With Mismatch Repair Deficiency Can Arise From Somatic, Rather Than Germline, Mutations

Functional analysis of BARD1 missense variants in homology-directed repair and damage sensitivity

Mek1 Down Regulates Rad51 Activity during Yeast Meiosis by Phosphorylation of Hed1

Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks

CSB-PGBD3 Mutations Cause Premature Ovarian Failure

The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3'-phosphatase in spinocerebellar ataxia type 3 pathogenesis

A Rad51-independent pathway promotes single-strand template repair in gene editing

DNA damage response factors from diverse pathways, including DNA crosslink repair, mediate alternative end joining

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