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Developing master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair

Neuroscience, 2007-04, Vol.145 (4), p.1280-1299

2007

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Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA

The EMBO journal, 1998-09, Vol.17 (17), p.5214-5226

1998

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Active and alkylated human AGT structures: a novel zinc site, inhibitor and extrahelical base binding

The EMBO journal, 2000-04, Vol.19 (7), p.1719-1730

2000

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Transplanted LDL and mannose‐6‐phosphate receptor internalization signals promote high‐efficiency endocytosis of the transferrin receptor

The EMBO journal, 1991-11, Vol.10 (11), p.3247-3253

1991

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N-terminal domain swapping and metal ion binding in nitric oxide synthase dimerization

The EMBO journal, 1999-11, Vol.18 (22), p.6271-6281

1999

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Crystallographic structure reveals phosphorylated pilin from Neisseria: phosphoserine sites modify type IV pilus surface chemistry and fibre morphology

Molecular microbiology, 1999-02, Vol.31 (3), p.743-752

1999

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Thermostabilization of recombinant human and bovine CuZn superoxide dismutases by replacement of free cysteines

Biochemical and biophysical research communications, 1991-11, Vol.181 (1), p.474-480

1991

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Inducible nitric oxide synthase: role of the N-terminal β-hairpin hook and pterin-binding segment in dimerization and tetrahydrobiopterin interaction

The EMBO journal, 1999-11, Vol.18 (22), p.6260-6270

1999

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Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template

Biochemistry and cell biology, 2007-08, Vol.85 (4), p.509

2007

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The pilus‐induced Ca2+ flux triggers lysosome exocytosis and increases the amount of Lamp1 accessible to Neisseria IgA1 protease

Cellular microbiology, 2001-04, Vol.3 (4), p.265-275

2001

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Crystallization and crystallographic characterization of the iron-sulfur-containing DNA-repair enzyme endonuclease III from Escherichia coli

Journal of molecular biology, 1992-09, Vol.227 (1), p.347-351

1992

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Dynamic XPD & Mrell-Rad50-Nbs1 DNA Repair Complexes: Disease-causing Mutations and Biological Outcomes

Journal of biomolecular structure & dynamics, 2011-06, Vol.28 (6), p.1094-1094

Tainer, JA

2011

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Structural basis for endothelial nitric oxide synthase binding to calmodulin

The EMBO journal, 2003-02, Vol.22 (4), p.766-775

2003

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Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2

The EMBO journal, 2003-09, Vol.22 (17), p.4566-4576

2003

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The pilus and porin of Neisseria gonorrhoeae cooperatively induce Ca2+ transients in infected epithelial cells

Cellular microbiology, 2005-12, Vol.7 (12), p.1736-1748

2005

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Synthesis and characterization of a recombinant myohemerythrin protein encoded by a synthetic gene

Gene, 1991-03, Vol.99 (2), p.151-156

1991

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Structural basis for endothelial nitric oxide synthase binding to calmodulin

The EMBO journal, 2003-03, Vol.22 (5), p.1234-1234

2003

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The role of arginine 143 in the electrostatics and mechanism of Cu,Zn peroxide dismutase: computational and experimental evaluation by mutational analysis

Proteins, structure, function, and bioinformatics, 1994, Vol.19 (1), p.24-34

1994

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Summary of `Superoxide Dismutase (SOD) and Free Radicals in Amyotrophic Lateral Sclerosis and Neurodegeneration' conference

Neurology, 1995-09, Vol.45 (9), p.1779-1780

1995

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The structure of human mitochondrial manganese superoxide dismutase reveals tetrameric interface of two 4-helix bundles

Cell, 1992, Vol.71 (1), p.107-118

1992

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SUMO-targeted ubiquitin ligase, Rad60, and Nse2 SUMO ligase suppress spontaneous Top1-mediated DNA damage and genome instability

PLoS genetics, 2011-03, Vol.7 (3), p.e1001320-e1001320

2011

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The nucleotide‐dependent interaction of FlaH and FlaI is essential for assembly and function of the archaellum motor

Molecular microbiology, 2016-02, Vol.99 (4), p.674-685

2016

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MP11-15 REAL-WORLD EVIDENCE OF 18F-FLUCICLOVINE PET/CT UTILIZATION FOR RECURRENT PROSTATE CANCER IN THE VETERAN AFFAIRS HEALTH SYSTEM

The Journal of urology, 2021-09, Vol.206 (Supplement 3)

2021

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Molecular mimicry of SUMO promotes DNA repair

Nature structural & molecular biology, 2009-05, Vol.16 (5), p.509-516

2009

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The DNA repair endonuclease XPG interacts directly and functionally with the WRN helicase defective in Werner syndrome

Cell cycle (Georgetown, Tex.), 2011-06, Vol.10 (12), p.1998-2007

2011

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Developing master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair

Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA

Active and alkylated human AGT structures: a novel zinc site, inhibitor and extrahelical base binding

Transplanted LDL and mannose‐6‐phosphate receptor internalization signals promote high‐efficiency endocytosis of the transferrin receptor

N-terminal domain swapping and metal ion binding in nitric oxide synthase dimerization

Crystallographic structure reveals phosphorylated pilin from Neisseria: phosphoserine sites modify type IV pilus surface chemistry and fibre morphology

Thermostabilization of recombinant human and bovine CuZn superoxide dismutases by replacement of free cysteines

Inducible nitric oxide synthase: role of the N-terminal β-hairpin hook and pterin-binding segment in dimerization and tetrahydrobiopterin interaction

Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template

The pilus‐induced Ca2+ flux triggers lysosome exocytosis and increases the amount of Lamp1 accessible to Neisseria IgA1 protease

Crystallization and crystallographic characterization of the iron-sulfur-containing DNA-repair enzyme endonuclease III from Escherichia coli

Dynamic XPD & Mrell-Rad50-Nbs1 DNA Repair Complexes: Disease-causing Mutations and Biological Outcomes

Structural basis for endothelial nitric oxide synthase binding to calmodulin

Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2

The pilus and porin of Neisseria gonorrhoeae cooperatively induce Ca2+ transients in infected epithelial cells

Synthesis and characterization of a recombinant myohemerythrin protein encoded by a synthetic gene

Structural basis for endothelial nitric oxide synthase binding to calmodulin

The role of arginine 143 in the electrostatics and mechanism of Cu,Zn peroxide dismutase: computational and experimental evaluation by mutational analysis

Summary of `Superoxide Dismutase (SOD) and Free Radicals in Amyotrophic Lateral Sclerosis and Neurodegeneration' conference

The structure of human mitochondrial manganese superoxide dismutase reveals tetrameric interface of two 4-helix bundles

SUMO-targeted ubiquitin ligase, Rad60, and Nse2 SUMO ligase suppress spontaneous Top1-mediated DNA damage and genome instability

The nucleotide‐dependent interaction of FlaH and FlaI is essential for assembly and function of the archaellum motor

MP11-15 REAL-WORLD EVIDENCE OF 18F-FLUCICLOVINE PET/CT UTILIZATION FOR RECURRENT PROSTATE CANCER IN THE VETERAN AFFAIRS HEALTH SYSTEM

Molecular mimicry of SUMO promotes DNA repair

The DNA repair endonuclease XPG interacts directly and functionally with the WRN helicase defective in Werner syndrome

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