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Role of DNA Mismatch Repair Defects in the Pathogenesis of Human Cancer

Journal of clinical oncology, 2003-03, Vol.21 (6), p.1174-1179

Päivi Peltomäki

2003

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Ten Years After Mutation Testing for Lynch Syndrome: Cancer Incidence and Outcome in Mutation-Positive and Mutation-Negative Family Members

Journal of clinical oncology, 2009-10, Vol.27 (28), p.4793-4797

2009

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Oncogenic Potential of Bisphenol A and Common Environmental Contaminants in Human Mammary Epithelial Cells

International journal of molecular sciences, 2020-05, Vol.21 (10), p.3735

2020

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Novel insights into tumorigenesis revealed by molecular analysis of Lynch syndrome cases with multiple colorectal tumors

Frontiers in oncology, 2024-04, Vol.14, p.1378392-1378392

2024

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Immunoprofiles and DNA Methylation of Inflammatory Marker Genes in Ulcerative Colitis-Associated Colorectal Tumorigenesis

Biomolecules (Basel, Switzerland), 2021-09, Vol.11 (10), p.1440

2021

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Mono- and biallelic germline variants of DNA glycosylase genes in colon adenomatous polyposis families from two continents

Frontiers in oncology, 2022-10, Vol.12, p.870863-870863

2022

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Molecular Basis of Mismatch Repair Protein Deficiency in Tumors from Lynch Suspected Cases with Negative Germline Test Results

Cancers, 2020-07, Vol.12 (7), p.1853

2020

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Distinct molecular profiles in Lynch syndrome‐associated and sporadic ovarian carcinomas

International journal of cancer, 2013-12, Vol.133 (11), p.2596-2608

2013

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DNA methylation changes and somatic mutations as tumorigenic events in Lynch syndrome-associated adenomas retaining mismatch repair protein expression

EBioMedicine, 2019-01, Vol.39, p.280-291

2019

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Mitotic abnormalities precede microsatellite instability in lynch syndrome-associated colorectal tumourigenesis

EBioMedicine, 2024-05, Vol.103, p.105111-105111, Article 105111

2024

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Epigenetic analysis of sporadic and Lynch-associated ovarian cancers reveals histology-specific patterns of DNA methylation

Epigenetics, 2014-12, Vol.9 (12), p.1577-1587

2014

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Cancer-predicting gene expression changes in colonic mucosa of Western diet fed Mlh1+/- mice

PloS one, 2013-10, Vol.8 (10), p.e76865-e76865

2013

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Identification of subgroup-specific miRNA patterns by epigenetic profiling of sporadic and Lynch syndrome-associated colorectal and endometrial carcinoma

Clinical epigenetics, 2015-03, Vol.7 (1), p.20-20, Article 20

2015

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Molecular Analysis of Familial Endometrial Carcinoma: A Manifestation of Hereditary Nonpolyposis Colorectal Cancer or a Separate Syndrome?

Journal of clinical oncology, 2005-07, Vol.23 (21), p.4609-4616

2005

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Clinicopathological Characterization and Genomic Aberrations in Subcutaneous Panniculitis-Like T-Cell Lymphoma

Journal of investigative dermatology, 2008-09, Vol.128 (9), p.2304-2309

2008

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DNA hypermethylation appears early and shows increased frequency with dysplasia in Lynch syndrome-associated colorectal adenomas and carcinomas

Clinical epigenetics, 2015-07, Vol.7 (1), p.71-71, Article 71

2015

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Altered Expression of MLH1, MSH2, and MSH6 in Predisposition to Hereditary Nonpolyposis Colorectal Cancer

Journal of clinical oncology, 2003-10, Vol.21 (19), p.3629-3637

2003

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Adenomatous Polyposis Families That Screen APC Mutation–Negative by Conventional Methods Are Genetically Heterogeneous

Journal of clinical oncology, 2005-08, Vol.23 (24), p.5651-5659

2005

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Loss of the wild type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer

Nature genetics, 1994-12, Vol.8 (4), p.405-410

1994

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Mutations associated with HNPCC predisposition -- Update of ICG-HNPCC/INSiGHT mutation database

Disease markers, 2004, Vol.20 (4-5), p.269-276

2004

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A New Tool for the Rapid Cloning of Amplified and Hypermethylated Human DNA Sequences from Restriction Landmark Genome Scanning Gels

Genomics (San Diego, Calif.), 1999-06, Vol.58 (3), p.254-262

1999

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Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients

Nature medicine, 1996-02, Vol.2 (2), p.169-174

1996

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Deficient DNA mismatch repair : a common etiologic factor for colon cancer: Reviews on molecular genetics of cancer

Human molecular genetics, 2001, Vol.10 (7), p.735-740

PELTOMÄKI, Päivi

2001

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Molecular Screening for Hereditary Nonpolyposis Colorectal Cancer: A Prospective, Population-Based Study

Journal of clinical oncology, 2001-10, Vol.19 (19), p.3944-3950

2001

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Aberrant CpG-island methylation has non-random and tumour-type-specific patterns

Nature genetics, 2000-02, Vol.24 (2), p.132-138

2000

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Role of DNA Mismatch Repair Defects in the Pathogenesis of Human Cancer

Ten Years After Mutation Testing for Lynch Syndrome: Cancer Incidence and Outcome in Mutation-Positive and Mutation-Negative Family Members

Oncogenic Potential of Bisphenol A and Common Environmental Contaminants in Human Mammary Epithelial Cells

Novel insights into tumorigenesis revealed by molecular analysis of Lynch syndrome cases with multiple colorectal tumors

Immunoprofiles and DNA Methylation of Inflammatory Marker Genes in Ulcerative Colitis-Associated Colorectal Tumorigenesis

Mono- and biallelic germline variants of DNA glycosylase genes in colon adenomatous polyposis families from two continents

Molecular Basis of Mismatch Repair Protein Deficiency in Tumors from Lynch Suspected Cases with Negative Germline Test Results

Distinct molecular profiles in Lynch syndrome‐associated and sporadic ovarian carcinomas

DNA methylation changes and somatic mutations as tumorigenic events in Lynch syndrome-associated adenomas retaining mismatch repair protein expression

Mitotic abnormalities precede microsatellite instability in lynch syndrome-associated colorectal tumourigenesis

Epigenetic analysis of sporadic and Lynch-associated ovarian cancers reveals histology-specific patterns of DNA methylation

Cancer-predicting gene expression changes in colonic mucosa of Western diet fed Mlh1+/- mice

Identification of subgroup-specific miRNA patterns by epigenetic profiling of sporadic and Lynch syndrome-associated colorectal and endometrial carcinoma

Molecular Analysis of Familial Endometrial Carcinoma: A Manifestation of Hereditary Nonpolyposis Colorectal Cancer or a Separate Syndrome?

Clinicopathological Characterization and Genomic Aberrations in Subcutaneous Panniculitis-Like T-Cell Lymphoma

DNA hypermethylation appears early and shows increased frequency with dysplasia in Lynch syndrome-associated colorectal adenomas and carcinomas

Altered Expression of MLH1, MSH2, and MSH6 in Predisposition to Hereditary Nonpolyposis Colorectal Cancer

Adenomatous Polyposis Families That Screen APC Mutation–Negative by Conventional Methods Are Genetically Heterogeneous

Loss of the wild type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer

Mutations associated with HNPCC predisposition -- Update of ICG-HNPCC/INSiGHT mutation database

A New Tool for the Rapid Cloning of Amplified and Hypermethylated Human DNA Sequences from Restriction Landmark Genome Scanning Gels

Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients

Deficient DNA mismatch repair : a common etiologic factor for colon cancer: Reviews on molecular genetics of cancer

Molecular Screening for Hereditary Nonpolyposis Colorectal Cancer: A Prospective, Population-Based Study

Aberrant CpG-island methylation has non-random and tumour-type-specific patterns

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