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Reversal of epigenetic aging and immunosenescent trends in humans

Aging cell, 2019-12, Vol.18 (6), p.e13028-n/a

2019

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Maternal blood contamination of collected cord blood can be identified using DNA methylation at three CpGs

Clinical epigenetics, 2017-07, Vol.9 (1), p.75-75, Article 75

2017

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Perinatally acquired HIV infection accelerates epigenetic aging in South African adolescents

AIDS (London), 2018-07, Vol.32 (11), p.1465-1474

2018

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Epigenetic age is associated with baseline and 3-year change in frailty in the Canadian Longitudinal Study on Aging

Clinical epigenetics, 2021-12, Vol.13 (1), p.163, Article 163

2021

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Methylation of cysteinyl leukotriene receptor 1 genes associates with lung function in asthmatics exposed to traffic-related air pollution

Epigenetics, 2021-02, Vol.16 (2), p.177-185

2021

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Optimized CRISPR-mediated gene knockin reveals FOXP3-independent maintenance of human Treg identity

Cell reports (Cambridge), 2021-08, Vol.36 (5), p.109494-109494, Article 109494

2021

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An in vitro chronic damage model impairs inflammatory and regenerative responses in human colonoid monolayers

Cell reports (Cambridge), 2022-01, Vol.38 (3), p.110283-110283, Article 110283

2022

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Maternal dysglycaemia, changes in the infant's epigenome modified with a diet and physical activity intervention in pregnancy: Secondary analysis of a randomised control trial

PLoS medicine, 2020-11, Vol.17 (11), p.e1003229

2020

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Rehabilitation Therapy Doses Are Low After Stroke and Predicted by Clinical Factors

Stroke (1970), 2023-03, Vol.54 (3), p.831-839

2023

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Lifetime and Acute Stress Predict Functional Outcomes Following Stroke: Findings From the Longitudinal STRONG Study

Stroke (1970), 2023-11, Vol.54 (11), p.2794-2803

2023

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Genetic Variation and Stroke Recovery: The STRONG Study

Stroke (1970), 2024-08, Vol.55 (8), p.2094-2102

2024

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Oxidative Stress Activates Endothelial Innate Immunity via Sterol Regulatory Element Binding Protein 2 (SREBP2) Transactivation of MicroRNA-92a

Circulation (New York, N.Y.), 2015-03, Vol.131 (9), p.805-814

2015

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Factors Influencing Intraocular Pressure Changes after Laser In Situ Keratomileusis with Flaps Created by Femtosecond Laser or Mechanical Microkeratome

PloS one, 2016-01, Vol.11 (1), p.e0147699-e0147699

2016

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Mononuclear-macrophages but not neutrophils act as major infiltrating anti-leptospiral phagocytes during leptospirosis

PloS one, 2017-07, Vol.12 (7), p.e0181014-e0181014

2017

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Novel Variance-Component TWAS method for studying complex human diseases with applications to Alzheimer's dementia

PLoS genetics, 2021-04, Vol.17 (4), p.e1009482-e1009482

2021

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Evaluation of the safety and immunogenicity of different COVID-19 vaccine combinations in healthy individuals: study protocol for a randomized, subject-blinded, controlled phase 3 trial [PRIBIVAC]

Trials, 2022-06, Vol.23 (1), p.498-13, Article 498

2022

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Collateral damage and CRISPR genome editing

PLoS genetics, 2019-03, Vol.15 (3), p.e1007994

2019

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TTI-621 (SIRPαFc), a CD47-blocking cancer immunotherapeutic, triggers phagocytosis of lymphoma cells by multiple polarized macrophage subsets

PloS one, 2017-10, Vol.12 (10), p.e0187262-e0187262

2017

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MuSK myasthenia gravis IgG4 disrupts the interaction of LRP4 with MuSK but both IgG4 and IgG1-3 can disperse preformed agrin-independent AChR clusters

PloS one, 2013-11, Vol.8 (11), p.e80695-e80695

2013

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Mitochondrial dysfunctions in leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL)

PloS one, 2019-10, Vol.14 (10), p.e0224173-e0224173

2019

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Validation of a hierarchical algorithm to define chronic liver disease and cirrhosis etiology in administrative healthcare data

PloS one, 2020-02, Vol.15 (2), p.e0229218-e0229218

2020

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Lung cancer mortality of residents living near petrochemical industrial complexes: a meta-analysis

Environmental health, 2017-09, Vol.16 (1), p.101-11, Article 101

2017

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Prevalence of neutralising antibodies against SARS-CoV-2 in acute infection and convalescence: A systematic review and meta-analysis

PLoS neglected tropical diseases, 2021-07, Vol.15 (7), p.e0009551-e0009551

2021

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Identification of CD24 as a cancer stem cell marker in human nasopharyngeal carcinoma

PloS one, 2014-06, Vol.9 (6), p.e99412

2014

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Reversal of epigenetic aging and immunosenescent trends in humans

Maternal blood contamination of collected cord blood can be identified using DNA methylation at three CpGs

Perinatally acquired HIV infection accelerates epigenetic aging in South African adolescents

Epigenetic age is associated with baseline and 3-year change in frailty in the Canadian Longitudinal Study on Aging

Methylation of cysteinyl leukotriene receptor 1 genes associates with lung function in asthmatics exposed to traffic-related air pollution

Optimized CRISPR-mediated gene knockin reveals FOXP3-independent maintenance of human Treg identity

An in vitro chronic damage model impairs inflammatory and regenerative responses in human colonoid monolayers

Maternal dysglycaemia, changes in the infant's epigenome modified with a diet and physical activity intervention in pregnancy: Secondary analysis of a randomised control trial

Rehabilitation Therapy Doses Are Low After Stroke and Predicted by Clinical Factors

Lifetime and Acute Stress Predict Functional Outcomes Following Stroke: Findings From the Longitudinal STRONG Study

Genetic Variation and Stroke Recovery: The STRONG Study

Oxidative Stress Activates Endothelial Innate Immunity via Sterol Regulatory Element Binding Protein 2 (SREBP2) Transactivation of MicroRNA-92a

Factors Influencing Intraocular Pressure Changes after Laser In Situ Keratomileusis with Flaps Created by Femtosecond Laser or Mechanical Microkeratome

Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay

Mononuclear-macrophages but not neutrophils act as major infiltrating anti-leptospiral phagocytes during leptospirosis

Novel Variance-Component TWAS method for studying complex human diseases with applications to Alzheimer's dementia

Evaluation of the safety and immunogenicity of different COVID-19 vaccine combinations in healthy individuals: study protocol for a randomized, subject-blinded, controlled phase 3 trial [PRIBIVAC]

Collateral damage and CRISPR genome editing

TTI-621 (SIRPαFc), a CD47-blocking cancer immunotherapeutic, triggers phagocytosis of lymphoma cells by multiple polarized macrophage subsets

MuSK myasthenia gravis IgG4 disrupts the interaction of LRP4 with MuSK but both IgG4 and IgG1-3 can disperse preformed agrin-independent AChR clusters

Mitochondrial dysfunctions in leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL)

Validation of a hierarchical algorithm to define chronic liver disease and cirrhosis etiology in administrative healthcare data

Lung cancer mortality of residents living near petrochemical industrial complexes: a meta-analysis

Prevalence of neutralising antibodies against SARS-CoV-2 in acute infection and convalescence: A systematic review and meta-analysis

Identification of CD24 as a cancer stem cell marker in human nasopharyngeal carcinoma

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