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Agmatine: clinical applications after 100 years in translation

Drug discovery today, 2013-09, Vol.18 (17-18), p.880-893

2013

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Agmatine protects against b-amyloid25-35-induced memory impairments in the rat

Neuroscience, 2010-08, Vol.169 (2), p.794-811

2010

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Agmatine attenuates chronic unpredictable mild stress-induced anxiety, depression-like behaviours and cognitive impairment by modulating nitrergic signalling pathway

Brain research, 2017-05, Vol.1663, p.66-77

2017

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Chronic agmatine treatment prevents behavioral manifestations of nicotine withdrawal in mice

European journal of pharmacology, 2015-05, Vol.754, p.190-198

2015

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The memory modulatory effect of agmatine in passive avoidance task coincides with alterations of hippocampal CaMKII-α and ERK signaling in mice

European journal of pharmacology, 2022-05, Vol.923, p.174928-174928, Article 174928

2022

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Neuroprotective offerings by agmatine

Neurotoxicology (Park Forest South), 2019-07, Vol.73, p.228-245

2019

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Cholestasis-Associated Pulmonary Inflammation, Oxidative Stress, and Tissue Fibrosis: The Protective Role of the Biogenic Amine Agmatine

Pharmacology, 2023-07, Vol.108 (4), p.379-393

2023

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Agmatine as a novel intervention for Alzheimer's disease: Pathological insights and cognitive benefits

Ageing research reviews, 2024-04, Vol.96, p.102269, Article 102269

2024

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Unveiling the reaction mechanism of arginine decarboxylase in Aspergillus oryzae: Insights from crystal structure analysis

Biochemical and biophysical research communications, 2024-11, Vol.733, p.150728, Article 150728

2024

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Neuroprotective Role of Agmatine in Neurological Diseases

Current neuropharmacology, 2018-01, Vol.16 (9), p.1296-1305

2018

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Agmatine ameliorates type 2 diabetes induced-Alzheimer's disease-like alterations in high-fat diet-fed mice via reactivation of blunted insulin signalling

Neuropharmacology, 2017-02, Vol.113 (Pt A), p.467-479

2017

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The expression of agmatinase manipulates the affective state of rats subjected to chronic restraint stress

Neuropharmacology, 2023-05, Vol.229, p.109476-109476, Article 109476

2023

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Agmatine-mediated inhibition of NMDA receptor expression and amelioration of dyskinesia via activation of Nrf2 and suppression of HMGB1/RAGE/TLR4/MYD88/NF-κB signaling cascade in rotenone lesioned rats

Life sciences (1973), 2022-12, Vol.311, p.121049-121049, Article 121049

2022

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Agmatine rescues autistic behaviors in the valproic acid-induced animal model of autism

Neuropharmacology, 2017-02, Vol.113 (Pt A), p.71-81

2017

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Therapeutic potential of agmatine for CNS disorders

Neurochemistry international, 2017-09, Vol.108, p.318-331

2017

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Long-term (5 years), high daily dosage of dietary agmatine--evidence of safety: a case report

Journal of medicinal food, 2014-11, Vol.17 (11), p.1256-1259

2014

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Agmatine (decarboxylated L-arginine): physiological role and therapeutic potential

Pharmacology & therapeutics (Oxford), 2012-03, Vol.133 (3), p.351-365

2012

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Neuroprotective action of agmatine in rotenone-induced model of Parkinson’s disease: Role of BDNF/cREB and ERK pathway

Behavioural brain research, 2020-08, Vol.392, p.112692-112692, Article 112692

2020

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Involvement of agmatine in antidepressant-like effect of HMG-CoA reductase inhibitors in mice

European journal of pharmacology, 2021-02, Vol.892, p.173739-173739, Article 173739

2021

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Agmatine Mitigates Inflammation-Related Oxidative Stress in BV-2 Cells by Inducing a Pre-Adaptive Response

International journal of molecular sciences, 2022-03, Vol.23 (7), p.3561

2022

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Agmatine abolishes restraint stress-induced depressive-like behavior and hippocampal antioxidant imbalance in mice

Progress in neuro-psychopharmacology & biological psychiatry, 2014-04, Vol.50, p.143-150

2014

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Agmatine requires GluN2B-containing NMDA receptors to inhibit the development of neuropathic pain

Molecular pain, 2021, Vol.17, p.17448069211029171-17448069211029171

2021

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Interfacial engineering and defect passivation of SnO2 through agmatine sulfate in carbon-based perovskite solar cells

Ceramics international, 2024-11, Vol.50 (21), p.43550-43562

2024

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Agmatine inhibits nicotine withdrawal induced cognitive deficits in inhibitory avoidance task in rats: Contribution of α 2 -adrenoceptors

Pharmacology, biochemistry and behavior, 2018-04, Vol.167, p.42-49

2018

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Safety and neurochemical profiles of acute and sub-chronic oral treatment with agmatine sulfate

Scientific reports, 2019-09, Vol.9 (1), p.12669-13, Article 12669

2019

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Agmatine: clinical applications after 100 years in translation

Agmatine protects against b-amyloid25-35-induced memory impairments in the rat

Agmatine attenuates chronic unpredictable mild stress-induced anxiety, depression-like behaviours and cognitive impairment by modulating nitrergic signalling pathway

Chronic agmatine treatment prevents behavioral manifestations of nicotine withdrawal in mice

The memory modulatory effect of agmatine in passive avoidance task coincides with alterations of hippocampal CaMKII-α and ERK signaling in mice

Neuroprotective offerings by agmatine

Cholestasis-Associated Pulmonary Inflammation, Oxidative Stress, and Tissue Fibrosis: The Protective Role of the Biogenic Amine Agmatine

Agmatine as a novel intervention for Alzheimer's disease: Pathological insights and cognitive benefits

Unveiling the reaction mechanism of arginine decarboxylase in Aspergillus oryzae: Insights from crystal structure analysis

Neuroprotective Role of Agmatine in Neurological Diseases

Agmatine ameliorates type 2 diabetes induced-Alzheimer's disease-like alterations in high-fat diet-fed mice via reactivation of blunted insulin signalling

The expression of agmatinase manipulates the affective state of rats subjected to chronic restraint stress

Agmatine-mediated inhibition of NMDA receptor expression and amelioration of dyskinesia via activation of Nrf2 and suppression of HMGB1/RAGE/TLR4/MYD88/NF-κB signaling cascade in rotenone lesioned rats

Agmatine rescues autistic behaviors in the valproic acid-induced animal model of autism

Therapeutic potential of agmatine for CNS disorders

Long-term (5 years), high daily dosage of dietary agmatine--evidence of safety: a case report

Agmatine (decarboxylated L-arginine): physiological role and therapeutic potential

Neuroprotective action of agmatine in rotenone-induced model of Parkinson’s disease: Role of BDNF/cREB and ERK pathway

Involvement of agmatine in antidepressant-like effect of HMG-CoA reductase inhibitors in mice

Agmatine Mitigates Inflammation-Related Oxidative Stress in BV-2 Cells by Inducing a Pre-Adaptive Response

Agmatine abolishes restraint stress-induced depressive-like behavior and hippocampal antioxidant imbalance in mice

Agmatine requires GluN2B-containing NMDA receptors to inhibit the development of neuropathic pain

Interfacial engineering and defect passivation of SnO2 through agmatine sulfate in carbon-based perovskite solar cells

Agmatine inhibits nicotine withdrawal induced cognitive deficits in inhibitory avoidance task in rats: Contribution of α 2 -adrenoceptors

Safety and neurochemical profiles of acute and sub-chronic oral treatment with agmatine sulfate

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