UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 28

Sortiert nach

Loss of function JAK1 mutations occur at high frequency in cancers with microsatellite instability and are suggestive of immune evasion

PloS one, 2017-11, Vol.12 (11), p.e0176181-e0176181

2017

Volltextzugriff (PDF)

Expansion of Bcr-Abl-Positive Leukemic Stem Cells Is Dependent on Hedgehog Pathway Activation

Cancer cell, 2008-09, Vol.14 (3), p.238-249

2008

Volltextzugriff (PDF)

Essential role of stromally induced hedgehog signaling in B-cell malignancies

Nature medicine, 2007-08, Vol.13 (8), p.944-951

2007

Volltextzugriff (PDF)

Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway

Nature medicine, 2010-12, Vol.16 (12), p.1429-1433

2010

Volltextzugriff (PDF)

Hedgehog pathway activation in chronic myeloid leukemia: A promise for a novel combination therapeutic approach?

Cell cycle (Georgetown, Tex.), 2010-09, Vol.9 (17), p.3449-3456

2010

Volltextzugriff (PDF)

Allosteric inhibition of BCR-ABL

Cell cycle (Georgetown, Tex.), 2010-09, Vol.9 (18), p.3734-3738

2010

Volltextzugriff (PDF)

SRC family kinases: potential targets for the treatment of human cancer and leukemia

Current pharmaceutical design, 2003-01, Vol.9 (25), p.2043

2003

Volltextzugriff (PDF)

A Conserved Salt Bridge in the G Loop of Multiple Protein Kinases Is Important for Catalysis and for In Vivo Lyn Function

Molecular cell, 2009-01, Vol.33 (1), p.43-52

2009

Volltextzugriff (PDF)

Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors

Nature (London), 2010-01, Vol.463 (7280), p.501-506

2010

Volltextzugriff (PDF)

Ba/F3 cells and their use in kinase drug discovery

Current opinion in oncology, 2007-01, Vol.19 (1), p.55-60

2007

Volltextzugriff (PDF)

H3B-6545, a selective estrogen receptor covalent antagonist, prevents bone loss in ovariectomized Sprague-Dawley rats

Journal of pharmacological and toxicological methods, 2019-09, Vol.99, p.106595, Article 106595

2019

Volltextzugriff (PDF)

Effect of a high-fat meal on the relative bioavailability of H3B-6527, a novel FGFR4 inhibitor, in healthy volunteers

Cancer chemotherapy and pharmacology, 2019-01, Vol.83 (1), p.91-96

2019

Volltextzugriff (PDF)

Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1 -induced B-lymphoblastic leukemia but not chronic myeloid leukemia

Nature genetics, 2004-05, Vol.36 (5), p.453-461

2004

Volltextzugriff (PDF)

Nonclinical pharmacokinetics and in vitro metabolism of H3B-6545, a novel selective ERα covalent antagonist (SERCA)

Cancer chemotherapy and pharmacology, 2019-01, Vol.83 (1), p.151-160

2019

Volltextzugriff (PDF)

Role of p21WAF1/CIP1 as an attenuator of both proliferative and drug-induced apoptotic signals in BCR-ABL-transformed hematopoietic cells

Annals of hematology, 2008-03, Vol.87 (3), p.183-193

2008

Volltextzugriff (PDF)

Inhibitors of the Abl kinase directed at either the ATP- or myristate-binding site

Biochimica et biophysica acta, 2010-03, Vol.1804 (3), p.454-462

2010

Volltextzugriff (PDF)

A General Strategy for Creating “Inactive-Conformation” Abl Inhibitors

Chemistry & biology, 2006-07, Vol.13 (7), p.779-786

2006

Volltextzugriff (PDF)

Clinical stage EGFR inhibitors irreversibly alkylate Bmx kinase

Bioorganic & medicinal chemistry, 2008-11, Vol.18 (22), p.5916-5919

2008

Volltextzugriff (PDF)

Role of p21(WAF1/CIP1) as an attenuator of both proliferative and drug-induced apoptotic signals in BCR-ABL-transformed hematopoietic cells

Annals of hematology, 2008-03, Vol.87 (3), p.183-193

2008

Volltextzugriff (PDF)

Profiling the kinome for drug discovery

Drug discovery today. Technologies, 2006-09, Vol.3 (3), p.269-276

2006

Volltextzugriff (PDF)

Nonmetastatic Medulloblastoma of Early Childhood: Results From the Prospective Clinical Trial HIT-2000 and An Extended Validation Cohort

Journal of clinical oncology, 2020-06, Vol.38 (18), p.2028-2040

2020

Volltextzugriff (PDF)

1 – 25 von 28

Suche als RSS-Feed

Aktive Filter

KollektionIngentaConnect

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(26)
Mit Volltextzugriff
(23)

Publikationsform

Artikel
(28)

Sprache

Englisch
(28)
Japanisch
(9)

Erscheinungsjahr

n.n

Thema

Science & Technology
(23)
Life Sciences & Biomedicine
(21)
Humans
(16)
Animals
(11)
Mice
(10)
Cell Biology
(8)
Cancer
(7)
Benzamides
(6)
Biochemistry & Molecular Biology
(6)
Genetic Aspects
(6)
Imatinib Mesylate
(6)
Oncology
(6)
Proteins
(6)
Biological And Medical Sciences
(5)
Fusion Proteins, Bcr-Abl - Metabolism
(5)
Health Aspects
(5)
Male
(5)
Medicine
(5)
Physiological Aspects
(5)
Piperazines - Pharmacology
(5)

15 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers

Loss of function JAK1 mutations occur at high frequency in cancers with microsatellite instability and are suggestive of immune evasion

Expansion of Bcr-Abl-Positive Leukemic Stem Cells Is Dependent on Hedgehog Pathway Activation

Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3′ Splice Site Selection through Use of a Different Branch Point

Essential role of stromally induced hedgehog signaling in B-cell malignancies

Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway

Hedgehog pathway activation in chronic myeloid leukemia: A promise for a novel combination therapeutic approach?

Allosteric inhibition of BCR-ABL

SRC family kinases: potential targets for the treatment of human cancer and leukemia

A Conserved Salt Bridge in the G Loop of Multiple Protein Kinases Is Important for Catalysis and for In Vivo Lyn Function

Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors

Ba/F3 cells and their use in kinase drug discovery

Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A - TCF7L2 fusion

H3B-6545, a selective estrogen receptor covalent antagonist, prevents bone loss in ovariectomized Sprague-Dawley rats

Effect of a high-fat meal on the relative bioavailability of H3B-6527, a novel FGFR4 inhibitor, in healthy volunteers

Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1 -induced B-lymphoblastic leukemia but not chronic myeloid leukemia

Nonclinical pharmacokinetics and in vitro metabolism of H3B-6545, a novel selective ERα covalent antagonist (SERCA)

Role of p21WAF1/CIP1 as an attenuator of both proliferative and drug-induced apoptotic signals in BCR-ABL-transformed hematopoietic cells

Inhibitors of the Abl kinase directed at either the ATP- or myristate-binding site

A General Strategy for Creating “Inactive-Conformation” Abl Inhibitors

Clinical stage EGFR inhibitors irreversibly alkylate Bmx kinase

Role of p21(WAF1/CIP1) as an attenuator of both proliferative and drug-induced apoptotic signals in BCR-ABL-transformed hematopoietic cells

Genomic sequencing of colorectal adenocarcinomas identifies a recurrent YTI1A-TCF7L2 fusion

Profiling the kinome for drug discovery

Nonmetastatic Medulloblastoma of Early Childhood: Results From the Prospective Clinical Trial HIT-2000 and An Extended Validation Cohort

Aktive Filter

Suchergebnisse filtern