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Development of small molecule non-peptide formyl peptide receptor (FPR) ligands and molecular modeling of their recognition

Current medicinal chemistry, 2014, Vol.21 (13), p.1478-1504

2014

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PDE5 inhibitors and their applications

Current medicinal chemistry, 2010-08, Vol.17 (24), p.2564-2587

2010

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Selective ACAT inhibitors as promising antihyperlipidemic, antiathero-sclerotic and anti-Alzheimer drugs

Mini reviews in medicinal chemistry, 2003, Vol.3 (6), p.576

2003

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Phosphodiesterase 4 inhibitors, structurally unrelated to Rolipram, as promising agents for the treatment of asthma and other pathologies

European Journal of Medicinal Chemistry, 2000-05, Vol.35 (5), p.463-480

2000

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4,5-Functionalized 6-phenyl-3(2 H)-pyridazinones: synthesis and evaluation of antinociceptive activity

European journal of medicinal chemistry, 1996, Vol.31 (1), p.65-70

1996

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Isoxazolo[3,4- d]pyridazinones and analogues as Leishmania mexicana PDE inhibitors

Farmaco (Società chimica italiana : 1989), 2002-02, Vol.57 (2), p.89-96

2002

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Synthesis of 4,5-functionalized-2-methyl-6-(substituted aryl)-3 (2H)-pyridazinones: a new group of potent platelet aggregation inhibitors

Farmaco (Società chimica italiana : 1989), 1997-03, Vol.52 (3), p.173

1997

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Antinociceptive activity of a 3(2H)-pyridazinone derivative in mice

Life sciences (1973), 1999, Vol.65 (13), p.1381-1394

1999

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5-Acetyl-2-methyl-4-nitro-6-phenyl-3(2H)-pyridazinone: Versatile Precursor to Hetero-Condensed Pyridazinones

Synthesis (Stuttgart), 1994, Vol.1994 (7), p.669-671

1994

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4-Substituted-5-acetyl-2-methyl-6-phenyl-3(2H)pyridazinones as PGE2 and IL-1 release inhibitors from mouse adherent macrophages

Pharmacological research, 1994-05, Vol.29 (4), p.367-372

1994

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Synthesis and evaluation of some 4,5-disubstituted 6-phenyl-3(2 H)-pyridazinones as hypotensive agents

European journal of medicinal chemistry, 1994, Vol.29 (3), p.249-252

1994

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PDE5 Inhibitors and their Applications

Current medicinal chemistry, 2010-05, Vol.999 (999), p.1-24

2010

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Heterocyclic-fused 3(2H)-pyridazinones as potent and selective PDE IV inhibitors: Further structure-activity relationships and molecular modelling studies

European journal of medicinal chemistry, 1998-10, Vol.33 (10), p.789-797

1998

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Isoxazolo [3,4-d]pyridazin-7(6h)-ones. synthesis of 3-unsubstituted derivatives: A reinvestigation

Tetrahedron letters, 1991-07, Vol.32 (27), p.3229-3230

1991

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Selective ACAT Inhibitors as Promising Antihyperlipidemic, Antiatherosclerotic and Anti-Alzheimer Drugs

Mini reviews in medicinal chemistry, 2003-09, Vol.3 (6), p.576-584

2003

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Diels-Alder reactions on 5-acetyl-2-methyl-4-nitro-6-phenyl-pyridazin-3(2H)-one : a new facet of the pyridazine system

Tetrahedron letters, 1993, Vol.34 (1), p.161-162

1993

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Reductive cleavage of isoxazolo[3,4-d]pyridazinones : a synthetic approach to various 4,5-functionalized 3(2H)-pyridazinones

Heterocycles, 1991-06, Vol.32 (6), p.1173-1179

1991

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New 6-cyano-3-phenyl-1-,2,3,4-tetrahydro-1,2-diazepin-5-ones: synthesis and in vitro antitumor activity evaluation

Farmaco (Società chimica italiana : 1989), 1991-03, Vol.46 (3), p.435

1991

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New synthetic approach to pyrazolo[3,4-d]pyridazin-7(6H)-one ring system

Heterocycles, 1989-08, Vol.29 (8), p.1595-1600

1989

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Airway relaxant and anti-inflammatory properties of a PDE4 inhibitor with low affinity for the high-affinity rolipram binding site

Naunyn-Schmiedeberg's archives of pharmacology, 2002-04, Vol.365 (4), p.284-289

2002

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Mono- and Di-substituted 5,6-Diphenyl-3-alkylaminopyridazines Active as ACAT Inhibitors

Heterocycles, 2002, Vol.57 (1), p.39

2002

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A new two-step procedure for functionalized-3(2H)-pyridazinones through homolytic substitution of 3-chloropyridazines

Tetrahedron letters, 1993-06, Vol.34 (24), p.3903-3906

1993

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5,6-Dinitrophenyl and 5-Aminophenyl-6-nitrophenyl Analogues of the ACAT Inhibitor 5,6-Diphenyl-3-alkylaminopyridazines

Heterocycles, 2000-12, Vol.53 (12), p.2709

2000

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New Synthesis of Differently Fused Pyridazinoquinolines

Synlett, 1999-09, Vol.1999 (9), p.1453-1455

1999

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Synthesis and evaluation of in vitro antitumor activity of some substituted 5-pyridazinyl-styrylketones

Farmaco (Società chimica italiana : 1989), 1991-07, Vol.46 (7-8), p.873

1991

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Development of small molecule non-peptide formyl peptide receptor (FPR) ligands and molecular modeling of their recognition

PDE5 inhibitors and their applications

Selective ACAT inhibitors as promising antihyperlipidemic, antiathero-sclerotic and anti-Alzheimer drugs

Phosphodiesterase 4 inhibitors, structurally unrelated to Rolipram, as promising agents for the treatment of asthma and other pathologies

4,5-Functionalized 6-phenyl-3(2 H)-pyridazinones: synthesis and evaluation of antinociceptive activity

Isoxazolo[3,4- d]pyridazinones and analogues as Leishmania mexicana PDE inhibitors

Synthesis of 4,5-functionalized-2-methyl-6-(substituted aryl)-3 (2H)-pyridazinones: a new group of potent platelet aggregation inhibitors

Antinociceptive activity of a 3(2H)-pyridazinone derivative in mice

5-Acetyl-2-methyl-4-nitro-6-phenyl-3(2H)-pyridazinone: Versatile Precursor to Hetero-Condensed Pyridazinones

4-Substituted-5-acetyl-2-methyl-6-phenyl-3(2H)pyridazinones as PGE2 and IL-1 release inhibitors from mouse adherent macrophages

Synthesis and evaluation of some 4,5-disubstituted 6-phenyl-3(2 H)-pyridazinones as hypotensive agents

PDE5 Inhibitors and their Applications

Heterocyclic-fused 3(2H)-pyridazinones as potent and selective PDE IV inhibitors: Further structure-activity relationships and molecular modelling studies

Isoxazolo [3,4-d]pyridazin-7(6h)-ones. synthesis of 3-unsubstituted derivatives: A reinvestigation

Selective ACAT Inhibitors as Promising Antihyperlipidemic, Antiatherosclerotic and Anti-Alzheimer Drugs

Diels-Alder reactions on 5-acetyl-2-methyl-4-nitro-6-phenyl-pyridazin-3(2H)-one : a new facet of the pyridazine system

Reductive cleavage of isoxazolo[3,4-d]pyridazinones : a synthetic approach to various 4,5-functionalized 3(2H)-pyridazinones

New 6-cyano-3-phenyl-1-,2,3,4-tetrahydro-1,2-diazepin-5-ones: synthesis and in vitro antitumor activity evaluation

New synthetic approach to pyrazolo[3,4-d]pyridazin-7(6H)-one ring system

Airway relaxant and anti-inflammatory properties of a PDE4 inhibitor with low affinity for the high-affinity rolipram binding site

Mono- and Di-substituted 5,6-Diphenyl-3-alkylaminopyridazines Active as ACAT Inhibitors

A new two-step procedure for functionalized-3(2H)-pyridazinones through homolytic substitution of 3-chloropyridazines

5,6-Dinitrophenyl and 5-Aminophenyl-6-nitrophenyl Analogues of the ACAT Inhibitor 5,6-Diphenyl-3-alkylaminopyridazines

New Synthesis of Differently Fused Pyridazinoquinolines

Synthesis and evaluation of in vitro antitumor activity of some substituted 5-pyridazinyl-styrylketones

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