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Anticancer activity of a Gold(I) phosphine thioredoxin reductase inhibitor in multiple myeloma

Redox biology, 2020-01, Vol.28, p.101310, Article 101310

2020

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Substrate and inhibitor specificities differ between human cytosolic and mitochondrial thioredoxin reductases: Implications for development of specific inhibitors

Free radical biology & medicine, 2011-03, Vol.50 (6), p.689-699

2011

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Platinum complexes act as shielding agents against virus infection

Chemical communications (Cambridge, England), 2021-05, Vol.57 (38), p.4666-4669

2021

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NanoSIMS multi-element imaging reveals internalisation and nucleolar targeting for a highly-charged polynuclear platinum compound

Chemical communications (Cambridge, England), 2013-08, Vol.49 (62), p.6944-6946

2013

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A gold(I) phosphine complex selectively induces apoptosis in breast cancer cells: Implications for anticancer therapeutics targeted to mitochondria

Biochemical pharmacology, 2007-10, Vol.74 (7), p.992-1002

2007

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Influence of geometric isomerism on the binding of platinum anticancer agents with phospholipids

Dalton transactions : an international journal of inorganic chemistry, 2019-07, Vol.48 (26), p.9791-98

2019

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Metalloglycomics of tris(2,2′-bipyridyl) cobalt and ruthenium compounds

Journal of inorganic biochemistry, 2022-04, Vol.229, p.111731-111731, Article 111731

2022

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Mechanisms of cytotoxicity and antitumor activity of gold(I) phosphine complexes: the possible role of mitochondria

Coordination chemistry reviews, 2002-10, Vol.232 (1), p.127-135

2002

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In vitro antitumour and hepatotoxicity profiles of Au(I) and Ag(I) bidentate pyridyl phosphine complexes and relationships to cellular uptake

Journal of inorganic biochemistry, 2008-02, Vol.102 (2), p.303-310

2008

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A new approach to glycan targeting: enzyme inhibition by oligosaccharide metalloshielding

Chemical communications (Cambridge, England), 2014-04, Vol.50 (31), p.4056-4058

2014

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Mitochondrial permeability transition induced by dinuclear gold(I)–carbene complexes: potential new antimitochondrial antitumour agents

Journal of inorganic biochemistry, 2004-10, Vol.98 (10), p.1642-1647

2004

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Bioenergetic differences selectively sensitize tumorigenic liver progenitor cells to a new gold(I) compound

Carcinogenesis (New York), 2008-06, Vol.29 (6), p.1124-1133

2008

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The stability of the cytochrome c scaffold as revealed by NMR spectroscopy

Journal of inorganic biochemistry, 2004-05, Vol.98 (5), p.814-823

2004

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Role of lipophilicity in determining cellular uptake and antitumour activity of gold phosphine complexes

Cancer chemotherapy and pharmacology, 2000, Vol.46 (5), p.343-350

2000

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Targeting the mitochondrial cell death pathway with gold compounds

Coordination chemistry reviews, 2007-07, Vol.251 (13), p.1889-1902

2007

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1,2-Bis(di-2-pyridylphosphino-yl)ethane

Acta crystallographica. Section E, Structure reports online, 2009-02, Vol.65 (Pt 3), p.o542-o542

2009

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Coordination complexes of silver(I) with tertiary phosphine and related ligands

Coordination chemistry reviews, 2009-02, Vol.253 (3), p.325-342

2009

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Electrochemical and spectroscopic studies on RuCl2(PPh3)2(N)2 and RuCl2(PPh3)2(N–N) complexes (N=pyridine derivatives and N–N=phenanthroline or bipyridine derivatives). X-ray structure of RuCl2(PPh3)2(phen)

Polyhedron, 2001-07, Vol.20 (17), p.2123-2128

2001

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The nature of the DNA template (single- versus double-stranded) affects the rate of aquation of a dinuclear Pt anticancer drug

Chemical communications (Cambridge, England), 2003-01 (1), p.122-123

2003

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Synthesis and structural characterisation of linear Au(I) N-heterocyclic carbene complexes: New analogues of the Au(I) phosphine drug Auranofin

Journal of organometallic chemistry, 2005-12, Vol.690 (24), p.5625-5635

2005

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Insights into the mechanism of action of platinum anticancer drugs from multinuclear NMR spectroscopy

Progress in nuclear magnetic resonance spectroscopy, 2006-08, Vol.49 (1), p.65-98

2006

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The nature of the DNA template (single- versus double-stranded) affects the rate of aquation of a dinuclear Pt anticancer drugElectronic supplementary information (ESI) available: experimental conditions for the NMR reactions, the models used for the kinetic fits and [1H,15N] HSQC NMR spectra of the final products from reactions of 1 with the single strand (I) (before and after addition of the complementary strand (II)), and with the duplex (III). See http://www.rsc.org/suppdata/cc/b2/b209661g

Chemical communications (Cambridge, England), 2003-12 (1), p.122-123

2003

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Convenient synthetic routes to bidentate and monodentate 2-, 3- and 4-pyridyl phosphines: potentially useful ligands for water-soluble complex catalysts

Journal of organometallic chemistry, 1998-03, Vol.554 (2), p.181-184

1998

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Rates of platination of - AG- and - GA- containing double-stranded oligonucleotides: effect of chloride concentration

Journal of inorganic biochemistry, 2000-04, Vol.79 (1), p.167-172

2000

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1,2‐Bis(di‐4‐pyridylphosphino)ethane (d4pype)

Acta crystallographica. Section E, Structure reports online, 2004-01, Vol.60 (1), p.o43-o44

2004

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Anticancer activity of a Gold(I) phosphine thioredoxin reductase inhibitor in multiple myeloma

Substrate and inhibitor specificities differ between human cytosolic and mitochondrial thioredoxin reductases: Implications for development of specific inhibitors

Platinum complexes act as shielding agents against virus infection

NanoSIMS multi-element imaging reveals internalisation and nucleolar targeting for a highly-charged polynuclear platinum compound

A gold(I) phosphine complex selectively induces apoptosis in breast cancer cells: Implications for anticancer therapeutics targeted to mitochondria

Influence of geometric isomerism on the binding of platinum anticancer agents with phospholipids

Metalloglycomics of tris(2,2′-bipyridyl) cobalt and ruthenium compounds

Mechanisms of cytotoxicity and antitumor activity of gold(I) phosphine complexes: the possible role of mitochondria

In vitro antitumour and hepatotoxicity profiles of Au(I) and Ag(I) bidentate pyridyl phosphine complexes and relationships to cellular uptake

A new approach to glycan targeting: enzyme inhibition by oligosaccharide metalloshielding

Mitochondrial permeability transition induced by dinuclear gold(I)–carbene complexes: potential new antimitochondrial antitumour agents

Bioenergetic differences selectively sensitize tumorigenic liver progenitor cells to a new gold(I) compound

The stability of the cytochrome c scaffold as revealed by NMR spectroscopy

Role of lipophilicity in determining cellular uptake and antitumour activity of gold phosphine complexes

Targeting the mitochondrial cell death pathway with gold compounds

1,2-Bis(di-2-pyridylphosphino-yl)ethane

Coordination complexes of silver(I) with tertiary phosphine and related ligands

Electrochemical and spectroscopic studies on RuCl2(PPh3)2(N)2 and RuCl2(PPh3)2(N–N) complexes (N=pyridine derivatives and N–N=phenanthroline or bipyridine derivatives). X-ray structure of RuCl2(PPh3)2(phen)

The nature of the DNA template (single- versus double-stranded) affects the rate of aquation of a dinuclear Pt anticancer drug

Synthesis and structural characterisation of linear Au(I) N-heterocyclic carbene complexes: New analogues of the Au(I) phosphine drug Auranofin

Insights into the mechanism of action of platinum anticancer drugs from multinuclear NMR spectroscopy

Convenient synthetic routes to bidentate and monodentate 2-, 3- and 4-pyridyl phosphines: potentially useful ligands for water-soluble complex catalysts

Rates of platination of - AG- and - GA- containing double-stranded oligonucleotides: effect of chloride concentration

1,2‐Bis(di‐4‐pyridylphosphino)ethane (d4pype)

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