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Thymidylate synthase inhibitors in cancer therapy: direct and indirect inhibitors

Journal of clinical oncology, 1997-01, Vol.15 (1), p.389-400

1997

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Carbamoylation of glutathione reductase by n,n-bis(2-chloroethyl)- n-nitrosourea associated with inhibition of multidrug resistance protein (MRP) function

Biochemical pharmacology, 1997-03, Vol.53 (6), p.801-809

1997

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Isolation and characterization of a human ileocecal carcinoma cell line (HCT-8) subclone resistant to fluorodeoxyuridine

Biochemical pharmacology, 1993-03, Vol.45 (5), p.1157-1164

1993

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Dimerization of mitochondrial Bax is associated with increased drug response in Bax-transfected A253 cells

Oncology research, 1999, Vol.11 (2), p.91

1999

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Role of Angiopoietin/Tie2 System in Sepsis: A Potential Therapeutic Target

Clinical and applied thrombosis/hemostasis, 2024-01, Vol.30, p.10760296241238010-10760296241238010

2024

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Cellular heterogeneity in DNA damage and growth inhibition induced by ICI D1694, thymidylate synthase inhibitor, using single cell assays

Biochemical pharmacology, 1994-08, Vol.48 (5), p.997-1002

1994

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Outcomes of endovascular salvage of clotted arteriovenous access and predictors of patency after thrombectomy

Journal of vascular surgery, 2020-04, Vol.71 (4), p.1333-1339

2020

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Cellular determinants of resistance to indolocarbazole analogue 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13(beta-D-glucopyranosyl)- 5H-indolo[2,3-alpha]pyrrolo[3,4-c]carbazole-5,7(6H)-dione (NB-506), a novel potent topoisomerase I inhibitor, in multidrug-resistant human tumor cells

Oncology research, 1997, Vol.9 (9), p.485

1997

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Aldosterone Receptor Antagonism Induces Reverse Remodeling When Added to Angiotensin Receptor Blockade in Chronic Heart Failure

Journal of the American College of Cardiology, 2007-08, Vol.50 (7), p.591-596

2007

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The Correlation Between FGB Promoter Polymorphism and Clotting Function in Patients With Idiopathic Lower Extremity Deep Venous Thrombosis

Clinical and applied thrombosis/hemostasis, 2021, Vol.27, p.1076029620967108-1076029620967108

2021

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Cyclin E–Cdk2 Activation Is Associated with Cell Cycle Arrest and Inhibition of DNA Replication Induced by the Thymidylate Synthase Inhibitor Tomudex

Experimental cell research, 1999-02, Vol.247 (1), p.189-199

1999

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Impact of Cardiac Contractility Modulation on Left Ventricular Global and Regional Function and Remodeling

JACC. Cardiovascular imaging, 2009-12, Vol.2 (12), p.1341-1349

2009

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Phosphorylation of chk1 at serine-345 affected by topoisomerase I poison SN-38

International journal of oncology, 2002-11, Vol.21 (5), p.1059

2002

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Mechanisms of resistance to N-[5-[ N-(3, 4-dihydro-2-methyl-4-oxoquinazolin-6-ylmethyl)- N-methylamino]-2-thenoyl]-L-glutamic acid (ZD1694), a folate-based thymidylate synthase inhibitor, in the HCT-8 human ileocecal adenocarcinoma cell line

Biochemical pharmacology, 1995-07, Vol.50 (3), p.391-398

1995

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Intramural Left Atrial Hematoma Complicating Catheter Ablation for Atrial Fibrillation

Journal of the American College of Cardiology, 2013-07, Vol.62 (3), p.252-252

2013

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Differential gene expression in peripheral blood T cells from patients with psoriasis, lichen planus, and atopic dermatitis

Journal of the American Academy of Dermatology, 2013-11, Vol.69 (5), p.e235-e243

2013

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Novel cellular determinants for reversal of multidrug resistance in cells expressing P170-glycoprotein

Biochimica et biophysica acta, 1998-03, Vol.1401 (3), p.265-276

1998

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Contrasting patterns of DNA fragmentation induced by thymidylate synthase inhibitors, ZD1694 and AG-331

Oncology research, 1995, Vol.7 (2), p.73

1995

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Feasibility of Measuring Renal Blood Flow Using Transesophageal Echocardiography in Pediatric Patients Undergoing Cardiac Surgery

Journal of cardiothoracic and vascular anesthesia, 2012-02, Vol.26 (1), p.39-45

2012

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Comparative DNA strand breakage induced by FUra and FdUrd in human ileocecal adenocarcinoma (HCT-8) cells: relevance to cell growth inhibition

Cancer communications (New York), 1991-02, Vol.3 (2), p.45

1991

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Down-regulation of c-myc gene expression with induction of high molecular weight DNA fragments by fluorodeoxyuridine

Biochemical pharmacology, 1994-07, Vol.48 (2), p.327-334

1994

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The Circle of Willis and White Matter Lesions in Patients with Carotid Atherosclerosis

Journal of stroke and cerebrovascular diseases, 2015-08, Vol.24 (8), p.1749-1754

2015

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Human papillomavirus vaccination in the resourced and resource-constrained world

Best practice & research. Clinical obstetrics & gynaecology, 2011-10, Vol.25 (5), p.597-603

2011

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Chk1 signaling pathways that mediated G2M checkpoint in relation to the cellular resistance to the novel topoisomerase I poison BNP1350

Biochemical and biophysical research communications, 2002-07, Vol.295 (2), p.435-444

2002

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Recent advances in the study of rTS proteins. rTS expression during growth and in response to thymidylate synthase inhibitors in human tumor cells

Advances in enzyme regulation, 1997, Vol.37, p.95-109

1997

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Thymidylate synthase inhibitors in cancer therapy: direct and indirect inhibitors

Carbamoylation of glutathione reductase by n,n-bis(2-chloroethyl)- n-nitrosourea associated with inhibition of multidrug resistance protein (MRP) function

Isolation and characterization of a human ileocecal carcinoma cell line (HCT-8) subclone resistant to fluorodeoxyuridine

Dimerization of mitochondrial Bax is associated with increased drug response in Bax-transfected A253 cells

Role of Angiopoietin/Tie2 System in Sepsis: A Potential Therapeutic Target

Cellular heterogeneity in DNA damage and growth inhibition induced by ICI D1694, thymidylate synthase inhibitor, using single cell assays

Outcomes of endovascular salvage of clotted arteriovenous access and predictors of patency after thrombectomy

Cellular determinants of resistance to indolocarbazole analogue 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13(beta-D-glucopyranosyl)- 5H-indolo[2,3-alpha]pyrrolo[3,4-c]carbazole-5,7(6H)-dione (NB-506), a novel potent topoisomerase I inhibitor, in multidrug-resistant human tumor cells

Aldosterone Receptor Antagonism Induces Reverse Remodeling When Added to Angiotensin Receptor Blockade in Chronic Heart Failure

The Correlation Between FGB Promoter Polymorphism and Clotting Function in Patients With Idiopathic Lower Extremity Deep Venous Thrombosis

Cyclin E–Cdk2 Activation Is Associated with Cell Cycle Arrest and Inhibition of DNA Replication Induced by the Thymidylate Synthase Inhibitor Tomudex

Impact of Cardiac Contractility Modulation on Left Ventricular Global and Regional Function and Remodeling

Phosphorylation of chk1 at serine-345 affected by topoisomerase I poison SN-38

Mechanisms of resistance to N-[5-[ N-(3, 4-dihydro-2-methyl-4-oxoquinazolin-6-ylmethyl)- N-methylamino]-2-thenoyl]-L-glutamic acid (ZD1694), a folate-based thymidylate synthase inhibitor, in the HCT-8 human ileocecal adenocarcinoma cell line

Intramural Left Atrial Hematoma Complicating Catheter Ablation for Atrial Fibrillation

Differential gene expression in peripheral blood T cells from patients with psoriasis, lichen planus, and atopic dermatitis

Novel cellular determinants for reversal of multidrug resistance in cells expressing P170-glycoprotein

Contrasting patterns of DNA fragmentation induced by thymidylate synthase inhibitors, ZD1694 and AG-331

Feasibility of Measuring Renal Blood Flow Using Transesophageal Echocardiography in Pediatric Patients Undergoing Cardiac Surgery

Comparative DNA strand breakage induced by FUra and FdUrd in human ileocecal adenocarcinoma (HCT-8) cells: relevance to cell growth inhibition

Down-regulation of c-myc gene expression with induction of high molecular weight DNA fragments by fluorodeoxyuridine

The Circle of Willis and White Matter Lesions in Patients with Carotid Atherosclerosis

Human papillomavirus vaccination in the resourced and resource-constrained world

Chk1 signaling pathways that mediated G2M checkpoint in relation to the cellular resistance to the novel topoisomerase I poison BNP1350

Recent advances in the study of rTS proteins. rTS expression during growth and in response to thymidylate synthase inhibitors in human tumor cells

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