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Evolutionary medicine and chronic inflammatory state—known and new concepts in pathophysiology

Journal of molecular medicine (Berlin, Germany), 2012-05, Vol.90 (5), p.523-534

Straub, Rainer H.

2012

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Substance P modulates bone remodeling properties of murine osteoblasts and osteoclasts

Scientific reports, 2018-06, Vol.8 (1), p.9199-15, Article 9199

2018

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Evolutionary medicine and bone loss in chronic inflammatory diseases—A theory of inflammation-related osteopenia

Seminars in arthritis and rheumatism, 2015-10, Vol.45 (2), p.220-228

2015

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Impact of the Sensory and Sympathetic Nervous System on Fracture Healing in Ovariectomized Mice

International journal of molecular sciences, 2020-01, Vol.21 (2), p.405

2020

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Proinflammatory α-Adrenergic Neuronal Regulation of Splenic IFN-γ, IL-6, and TGF-β of Mice from Day 15 onwards in Arthritis

Neuroimmunomodulation, 2020-07, Vol.27 (1), p.58-68

2020

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Differential inflammation-mediated function of prokineticin 2 in the synovial fibroblasts of patients with rheumatoid arthritis compared with osteoarthritis

Scientific reports, 2021-09, Vol.11 (1), p.18399-18399, Article 18399

2021

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Anti-Inflammatory Effects of Endogenously Released Adenosine in Synovial Cells of Osteoarthritis and Rheumatoid Arthritis Patients

International journal of molecular sciences, 2021-08, Vol.22 (16), p.8956

2021

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A thyroid hormone network exists in synovial fibroblasts of rheumatoid arthritis and osteoarthritis patients

Scientific reports, 2019-09, Vol.9 (1), p.13235-14, Article 13235

2019

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Norepinephrine Inhibits the Proliferation of Human Bone Marrow-Derived Mesenchymal Stem Cells via β2-Adrenoceptor-Mediated ERK1/2 and PKA Phosphorylation

International journal of molecular sciences, 2020-05, Vol.21 (11), p.3924

2020

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Function of the sympathetic supply in acute and chronic experimental joint inflammation

Autonomic neuroscience, 2014-05, Vol.182, p.55-64

2014

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Absence of substance P and the sympathetic nervous system impact on bone structure and chondrocyte differentiation in an adult model of endochondral ossification

Matrix biology, 2014-09, Vol.38, p.22-35

2014

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Norepinephrine Inhibits Synovial Adipose Stem Cell Chondrogenesis via α2a-Adrenoceptor-Mediated ERK1/2 Activation

International journal of molecular sciences, 2019-06, Vol.20 (13), p.3127

2019

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β2-Adrenoceptor Deficiency Results in Increased Calcified Cartilage Thickness and Subchondral Bone Remodeling in Murine Experimental Osteoarthritis

Frontiers in immunology, 2022-01, Vol.12, p.801505-801505

2022

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Circadian rhythms in arthritis: Hormonal effects on the immune/inflammatory reaction

Autoimmunity reviews, 2008-01, Vol.7 (3), p.223-228

2008

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Complexity of the bi-directional neuroimmune junction in the spleen

Trends in pharmacological sciences (Regular ed.), 2004-12, Vol.25 (12), p.640-646

Straub, Rainer H.

2004

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Glucocorticoids and chronic inflammation

Rheumatology (Oxford, England), 2016-12, Vol.55 (suppl 2), p.ii6-ii14

2016

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Low density of sympathetic nerve fibers relative to substance P-positive nerve fibers in lesional skin of chronic pruritus and prurigo nodularis

Journal of dermatological science, 2010-06, Vol.58 (3), p.193-197

2010

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β2-adrenoceptors kick osteoarthritis – Time to rethink prevention and therapy

Osteoarthritis and cartilage, 2024-06

2024

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Role of neuroendocrine and neuroimmune mechanisms in chronic inflammatory rheumatic diseases—The 10-year update

Seminars in arthritis and rheumatism, 2013-12, Vol.43 (3), p.392-404

2013

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The memory of the fatty acid system

Progress in lipid research, 2020-07, Vol.79, p.101049-101049, Article 101049

Straub, Rainer H.

2020

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Sympathetic Neurotransmitters Modulate Osteoclastogenesis and Osteoclast Activity in the Context of Collagen-Induced Arthritis

PloS one, 2015-10, Vol.10 (10), p.e0139726-e0139726

2015

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TRPV1, TRPA1, and TRPM8 channels in inflammation, energy redirection, and water retention: role in chronic inflammatory diseases with an evolutionary perspective

Journal of molecular medicine (Berlin, Germany), 2014-09, Vol.92 (9), p.925-937

Straub, Rainer H.

2014

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New Editor-in-Chief’s Note: The Past and the Future

Neuroimmunomodulation, 2022-01, Vol.29 (1), p.1-3

Straub, Rainer H.

2022

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Fatigue in inflammatory rheumatic disorders: pathophysiological mechanisms

Rheumatology (Oxford, England), 2019-11, Vol.58 (Supplement_5), p.v35-v50

2019

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Medically Unexplained Symptoms Are Linked to Chronic Inflammatory Diseases: Is There a Role for Frontal Cerebral Blood Oxygen Content?

Neuroimmunomodulation, 2024, Vol.31 (1), p.40-50

2024

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Evolutionary medicine and chronic inflammatory state—known and new concepts in pathophysiology

Substance P modulates bone remodeling properties of murine osteoblasts and osteoclasts

Evolutionary medicine and bone loss in chronic inflammatory diseases—A theory of inflammation-related osteopenia

Impact of the Sensory and Sympathetic Nervous System on Fracture Healing in Ovariectomized Mice

Proinflammatory α-Adrenergic Neuronal Regulation of Splenic IFN-γ, IL-6, and TGF-β of Mice from Day 15 onwards in Arthritis

Differential inflammation-mediated function of prokineticin 2 in the synovial fibroblasts of patients with rheumatoid arthritis compared with osteoarthritis

Anti-Inflammatory Effects of Endogenously Released Adenosine in Synovial Cells of Osteoarthritis and Rheumatoid Arthritis Patients

A thyroid hormone network exists in synovial fibroblasts of rheumatoid arthritis and osteoarthritis patients

Norepinephrine Inhibits the Proliferation of Human Bone Marrow-Derived Mesenchymal Stem Cells via β2-Adrenoceptor-Mediated ERK1/2 and PKA Phosphorylation

Function of the sympathetic supply in acute and chronic experimental joint inflammation

Absence of substance P and the sympathetic nervous system impact on bone structure and chondrocyte differentiation in an adult model of endochondral ossification

Norepinephrine Inhibits Synovial Adipose Stem Cell Chondrogenesis via α2a-Adrenoceptor-Mediated ERK1/2 Activation

β2-Adrenoceptor Deficiency Results in Increased Calcified Cartilage Thickness and Subchondral Bone Remodeling in Murine Experimental Osteoarthritis

Circadian rhythms in arthritis: Hormonal effects on the immune/inflammatory reaction

Complexity of the bi-directional neuroimmune junction in the spleen

Glucocorticoids and chronic inflammation

Low density of sympathetic nerve fibers relative to substance P-positive nerve fibers in lesional skin of chronic pruritus and prurigo nodularis

β2-adrenoceptors kick osteoarthritis – Time to rethink prevention and therapy

Role of neuroendocrine and neuroimmune mechanisms in chronic inflammatory rheumatic diseases—The 10-year update

The memory of the fatty acid system

Sympathetic Neurotransmitters Modulate Osteoclastogenesis and Osteoclast Activity in the Context of Collagen-Induced Arthritis

TRPV1, TRPA1, and TRPM8 channels in inflammation, energy redirection, and water retention: role in chronic inflammatory diseases with an evolutionary perspective

New Editor-in-Chief’s Note: The Past and the Future

Fatigue in inflammatory rheumatic disorders: pathophysiological mechanisms

Medically Unexplained Symptoms Are Linked to Chronic Inflammatory Diseases: Is There a Role for Frontal Cerebral Blood Oxygen Content?

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