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The outs and the ins of sphingosine-1-phosphate in immunity

Nature reviews. Immunology, 2011-06, Vol.11 (6), p.403-415

2011

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Lysophospholipid receptor nomenclature review: IUPHAR Review 8

British journal of pharmacology, 2014-08, Vol.171 (15), p.3575-3594

2014

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Revisiting the sphingolipid rheostat: Evolving concepts in cancer therapy

Experimental cell research, 2015-05, Vol.333 (2), p.195-200

2015

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Sphingolipids in metabolic disease: The good, the bad, and the unknown

Cell metabolism, 2021-07, Vol.33 (7), p.1293-1306

2021

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ORMDL3 and allergic asthma: From physiology to pathology

Journal of allergy and clinical immunology, 2019-09, Vol.144 (3), p.634-640

2019

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Role of Sphingosine Kinase 1 and Sphingosine-1-Phosphate Axis in Hepatocellular Carcinoma

Lipid Signaling in Human Diseases, 2020-01, p.3-17

2020

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A specific sphingosine kinase 1 inhibitor attenuates airway hyperresponsiveness and inflammation in a mast cell–dependent murine model of allergic asthma

Journal of allergy and clinical immunology, 2013-02, Vol.131 (2), p.501-511.e1

2013

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Sphingosine-1-Phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-Associated Cancer

Cancer cell, 2013-01, Vol.23 (1), p.107-120

2013

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Targeting SphK1 as a new strategy against cancer

Current drug targets, 2008-08, Vol.9 (8), p.662-673

2008

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Autocrine and paracrine roles of sphingosine-1-phosphate

Trends in endocrinology and metabolism, 2007-10, Vol.18 (8), p.300-307

2007

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Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

Nature (London), 2010-06, Vol.465 (7301), p.1084-1088

2010

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Ceramide in apoptosis and oxidative stress in allergic inflammation and asthma

Journal of allergy and clinical immunology, 2021-05, Vol.147 (5), p.1936-1948.e9

2021

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Sphingosine kinase 1/S1P receptor signaling axis is essential for cellular uptake of Neisseria meningitidis in brain endothelial cells

PLoS pathogens, 2023-11, Vol.19 (11), p.e1011842-e1011842

2023

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Conjugated bile acid–activated S1P receptor 2 is a key regulator of sphingosine kinase 2 and hepatic gene expression

Hepatology (Baltimore, Md.), 2015-04, Vol.61 (4), p.1216-1226

2015

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Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes

Hepatology (Baltimore, Md.), 2012-01, Vol.55 (1), p.267-276

2012

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Targeting the S1P/S1PR1 axis mitigates cancer-induced bone pain and neuroinflammation

Pain (Amsterdam), 2017-09, Vol.158 (9), p.1733-1742

2017

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Resection of the primary tumor improves survival in metastatic breast cancer by reducing overall tumor burden

Surgery, 2013-06, Vol.153 (6), p.771-778

2013

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Export and functions of sphingosine-1-phosphate

Biochimica et biophysica acta, 2009-07, Vol.1791 (7), p.692-696

2009

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Sphingosine-1-phosphate and estrogen signaling in breast cancer

Advances in biological regulation, 2016-01, Vol.60, p.160-165

2016

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Aberrant ORM (yeast)–like protein isoform 3 (ORMDL3) expression dysregulates ceramide homeostasis in cells and ceramide exacerbates allergic asthma in mice

Journal of allergy and clinical immunology, 2015-10, Vol.136 (4), p.1035-1046.e6

2015

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Targeting sphingosine-1-phosphate: A novel avenue for cancer therapeutics

Cancer cell, 2006-03, Vol.9 (3), p.148-150

2006

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The sphingosine-1-phosphate/sphingosine-1-phosphate receptor 2 axis regulates early airway T-cell infiltration in murine mast cell–dependent acute allergic responses

Journal of allergy and clinical immunology, 2015-04, Vol.135 (4), p.1008-1018.e1

2015

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Biological characterization of 3-(2-amino-ethyl)-5-[3-(4-butoxyl-phenyl)-propylidene]-thiazolidine-2,4-dione (K145) as a selective sphingosine kinase-2 inhibitor and anticancer agent

PloS one, 2013-02, Vol.8 (2), p.e56471-e56471

2013

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Sphingosine-1-phosphate: signaling inside and out

FEBS Letters, 2000-06, Vol.476 (1), p.55-57

2000

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Sphingosine-1-phosphate receptor subtype 1 activation in the central nervous system contributes to morphine withdrawal in rodents

Journal of neuroinflammation, 2020-10, Vol.17 (1), p.1-314, Article 314

2020

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The outs and the ins of sphingosine-1-phosphate in immunity

Lysophospholipid receptor nomenclature review: IUPHAR Review 8

Revisiting the sphingolipid rheostat: Evolving concepts in cancer therapy

Sphingolipids in metabolic disease: The good, the bad, and the unknown

ORMDL3 and allergic asthma: From physiology to pathology

Role of Sphingosine Kinase 1 and Sphingosine-1-Phosphate Axis in Hepatocellular Carcinoma

A specific sphingosine kinase 1 inhibitor attenuates airway hyperresponsiveness and inflammation in a mast cell–dependent murine model of allergic asthma

Sphingosine-1-Phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-Associated Cancer

Targeting SphK1 as a new strategy against cancer

Autocrine and paracrine roles of sphingosine-1-phosphate

Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

Ceramide in apoptosis and oxidative stress in allergic inflammation and asthma

Sphingosine kinase 1/S1P receptor signaling axis is essential for cellular uptake of Neisseria meningitidis in brain endothelial cells

Conjugated bile acid–activated S1P receptor 2 is a key regulator of sphingosine kinase 2 and hepatic gene expression

Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes

Targeting the S1P/S1PR1 axis mitigates cancer-induced bone pain and neuroinflammation

Resection of the primary tumor improves survival in metastatic breast cancer by reducing overall tumor burden

Export and functions of sphingosine-1-phosphate

Sphingosine-1-phosphate and estrogen signaling in breast cancer

Aberrant ORM (yeast)–like protein isoform 3 (ORMDL3) expression dysregulates ceramide homeostasis in cells and ceramide exacerbates allergic asthma in mice

Targeting sphingosine-1-phosphate: A novel avenue for cancer therapeutics

The sphingosine-1-phosphate/sphingosine-1-phosphate receptor 2 axis regulates early airway T-cell infiltration in murine mast cell–dependent acute allergic responses

Biological characterization of 3-(2-amino-ethyl)-5-[3-(4-butoxyl-phenyl)-propylidene]-thiazolidine-2,4-dione (K145) as a selective sphingosine kinase-2 inhibitor and anticancer agent

Sphingosine-1-phosphate: signaling inside and out

Sphingosine-1-phosphate receptor subtype 1 activation in the central nervous system contributes to morphine withdrawal in rodents

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