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Role of DNA Mismatch Repair Defects in the Pathogenesis of Human Cancer

Journal of clinical oncology, 2003-03, Vol.21 (6), p.1174-1179

Päivi Peltomäki

2003

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Mutations and epimutations in the origin of cancer

Experimental cell research, 2012-02, Vol.318 (4), p.299-310

Peltomaeki, Paeivi

2012

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Germline Mutation of RPS20 , Encoding a Ribosomal Protein, Causes Predisposition to Hereditary Nonpolyposis Colorectal Carcinoma Without DNA Mismatch Repair Deficiency

Gastroenterology (New York, N.Y. 1943), 2014-09, Vol.147 (3), p.595-598.e5

2014

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Ten Years After Mutation Testing for Lynch Syndrome: Cancer Incidence and Outcome in Mutation-Positive and Mutation-Negative Family Members

Journal of clinical oncology, 2009-10, Vol.27 (28), p.4793-4797

2009

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Gene fusions and oncogenic mutations in MLH1 deficient and BRAFV600E wild-type colorectal cancers

Virchows Archiv : an international journal of pathology, 2022-04, Vol.480 (4), p.807-817

2022

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Oncogenic Potential of Bisphenol A and Common Environmental Contaminants in Human Mammary Epithelial Cells

International journal of molecular sciences, 2020-05, Vol.21 (10), p.3735

2020

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Novel insights into tumorigenesis revealed by molecular analysis of Lynch syndrome cases with multiple colorectal tumors

Frontiers in oncology, 2024-04, Vol.14, p.1378392-1378392

2024

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BRAF mutation in sporadic colorectal cancer and Lynch syndrome

Virchows Archiv : an international journal of pathology, 2013-11, Vol.463 (5), p.613-621

2013

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Converging endometrial and ovarian tumorigenesis in Lynch syndrome: Shared origin of synchronous carcinomas

Gynecologic oncology, 2018-07, Vol.150 (1), p.92-98

2018

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Body Weight, Physical Activity, and Risk of Cancer in Lynch Syndrome

Cancers, 2021-04, Vol.13 (8), p.1849

2021

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LINE-1 hypomethylation in familial and sporadic cancer

Journal of molecular medicine (Berlin, Germany), 2012-07, Vol.90 (7), p.827-835

2012

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Molecular Basis of Mismatch Repair Protein Deficiency in Tumors from Lynch Suspected Cases with Negative Germline Test Results

Cancers, 2020-07, Vol.12 (7), p.1853

2020

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Immunoprofiles and DNA Methylation of Inflammatory Marker Genes in Ulcerative Colitis-Associated Colorectal Tumorigenesis

Biomolecules (Basel, Switzerland), 2021-09, Vol.11 (10), p.1440

2021

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Testing for Lynch Syndrome in Endometrial Carcinoma: From Universal to Age-Selective MLH1 Methylation Analysis

Cancers, 2022-03, Vol.14 (5), p.1348

2022

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Thyroid Carcinomas That Occur in Familial Adenomatous Polyposis Patients Recurrently Harbor Somatic Variants in APC , BRAF , and KTM2D

Thyroid (New York, N.Y.), 2020-03, Vol.30 (3), p.380-388

2020

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Mlh1 deficiency in normal mouse colon mucosa associates with chromosomally unstable colon cancer

Carcinogenesis (New York), 2018-05, Vol.39 (6), p.788-797

2018

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Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer

Gastroenterology (New York, N.Y. 1943), 2000-05, Vol.118 (5), p.829-834

2000

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Mono- and biallelic germline variants of DNA glycosylase genes in colon adenomatous polyposis families from two continents

Frontiers in oncology, 2022-10, Vol.12, p.870863-870863

2022

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Mitotic abnormalities precede microsatellite instability in lynch syndrome-associated colorectal tumourigenesis

EBioMedicine, 2024-05, Vol.103, p.105111-105111, Article 105111

2024

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Development of Colorectal Tumors in Colonoscopic Surveillance in Lynch Syndrome

Gastroenterology (New York, N.Y. 1943), 2007-10, Vol.133 (4), p.1093-1098

2007

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DNA methylation changes and somatic mutations as tumorigenic events in Lynch syndrome-associated adenomas retaining mismatch repair protein expression

EBioMedicine, 2019-01, Vol.39, p.280-291

2019

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BMPR1A Mutations in Hereditary Nonpolyposis Colorectal Cancer Without Mismatch Repair Deficiency

Gastroenterology (New York, N.Y. 1943), 2011-07, Vol.141 (1), p.e23-e26

2011

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Identification of subgroup-specific miRNA patterns by epigenetic profiling of sporadic and Lynch syndrome-associated colorectal and endometrial carcinoma

Clinical epigenetics, 2015-03, Vol.7 (1), p.20-20, Article 20

2015

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The genetics of HNPCC: Application to diagnosis and screening

Critical reviews in oncology/hematology, 2006-06, Vol.58 (3), p.208-220

2006

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Molecular Analysis of Familial Endometrial Carcinoma: A Manifestation of Hereditary Nonpolyposis Colorectal Cancer or a Separate Syndrome?

Journal of clinical oncology, 2005-07, Vol.23 (21), p.4609-4616

2005

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Role of DNA Mismatch Repair Defects in the Pathogenesis of Human Cancer

Mutations and epimutations in the origin of cancer

Germline Mutation of RPS20 , Encoding a Ribosomal Protein, Causes Predisposition to Hereditary Nonpolyposis Colorectal Carcinoma Without DNA Mismatch Repair Deficiency

Ten Years After Mutation Testing for Lynch Syndrome: Cancer Incidence and Outcome in Mutation-Positive and Mutation-Negative Family Members

Gene fusions and oncogenic mutations in MLH1 deficient and BRAFV600E wild-type colorectal cancers

Oncogenic Potential of Bisphenol A and Common Environmental Contaminants in Human Mammary Epithelial Cells

Novel insights into tumorigenesis revealed by molecular analysis of Lynch syndrome cases with multiple colorectal tumors

BRAF mutation in sporadic colorectal cancer and Lynch syndrome

Converging endometrial and ovarian tumorigenesis in Lynch syndrome: Shared origin of synchronous carcinomas

Body Weight, Physical Activity, and Risk of Cancer in Lynch Syndrome

LINE-1 hypomethylation in familial and sporadic cancer

Molecular Basis of Mismatch Repair Protein Deficiency in Tumors from Lynch Suspected Cases with Negative Germline Test Results

Immunoprofiles and DNA Methylation of Inflammatory Marker Genes in Ulcerative Colitis-Associated Colorectal Tumorigenesis

Testing for Lynch Syndrome in Endometrial Carcinoma: From Universal to Age-Selective MLH1 Methylation Analysis

Thyroid Carcinomas That Occur in Familial Adenomatous Polyposis Patients Recurrently Harbor Somatic Variants in APC , BRAF , and KTM2D

Mlh1 deficiency in normal mouse colon mucosa associates with chromosomally unstable colon cancer

Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer

Mono- and biallelic germline variants of DNA glycosylase genes in colon adenomatous polyposis families from two continents

Mitotic abnormalities precede microsatellite instability in lynch syndrome-associated colorectal tumourigenesis

Development of Colorectal Tumors in Colonoscopic Surveillance in Lynch Syndrome

DNA methylation changes and somatic mutations as tumorigenic events in Lynch syndrome-associated adenomas retaining mismatch repair protein expression

BMPR1A Mutations in Hereditary Nonpolyposis Colorectal Cancer Without Mismatch Repair Deficiency

Identification of subgroup-specific miRNA patterns by epigenetic profiling of sporadic and Lynch syndrome-associated colorectal and endometrial carcinoma

The genetics of HNPCC: Application to diagnosis and screening

Molecular Analysis of Familial Endometrial Carcinoma: A Manifestation of Hereditary Nonpolyposis Colorectal Cancer or a Separate Syndrome?

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