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Identification of Senescent Cells in the Bone Microenvironment

Journal of bone and mineral research, 2016-11, Vol.31 (11), p.1920-1929

2016

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Periodontal Disease and Senescent Cells: New Players for an Old Oral Health Problem?

International journal of molecular sciences, 2020-10, Vol.21 (20), p.7441

2020

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The role of senolytics in osteoporosis and other skeletal pathologies

Mechanisms of ageing and development, 2021-10, Vol.199, p.111565-111565, Article 111565

2021

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Effects of Age and Estrogen on Skeletal Gene Expression in Humans as Assessed by RNA Sequencing

PloS one, 2015-09, Vol.10 (9), p.e0138347-e0138347

2015

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Effects of age on bone mRNA levels of sclerostin and other genes relevant to bone metabolism in humans

Bone (New York, N.Y.), 2014-02, Vol.59, p.1-6

2014

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Calcium mimics the chemotactic effect of conditioned media and is an effective inducer of bone regeneration

PloS one, 2019-01, Vol.14 (1), p.e0210301-e0210301

2019

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Estrogen and the skeleton

Trends in endocrinology and metabolism, 2012-11, Vol.23 (11), p.576-581

2012

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Dissection of estrogen receptor alpha signaling pathways in osteoblasts using RNA-sequencing

PloS one, 2014-04, Vol.9 (4), p.e95987-e95987

2014

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Global transcriptional profiling using RNA sequencing and DNA methylation patterns in highly enriched mesenchymal cells from young versus elderly women

Bone (New York, N.Y.), 2015-07, Vol.76, p.49-57

2015

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Targeting cellular senescence prevents age-related bone loss in mice

Nature medicine, 2017-09, Vol.23 (9), p.1072-1079

2017

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Update on Wnt signaling in bone cell biology and bone disease

Gene, 2012-01, Vol.492 (1), p.1-18

2012

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LPS-induced premature osteocyte senescence: Implications in inflammatory alveolar bone loss and periodontal disease pathogenesis

Bone (New York, N.Y.), 2020-03, Vol.132, p.115220-115220, Article 115220

2020

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miRNAs in osteoclast biology

Bone (New York, N.Y.), 2021-02, Vol.143, p.115757-115757, Article 115757

2021

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Independent Roles of Estrogen Deficiency and Cellular Senescence in the Pathogenesis of Osteoporosis: Evidence in Young Adult Mice and Older Humans

Journal of bone and mineral research, 2019-08, Vol.34 (8), p.1407-1418

2019

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Targeted Reduction of Senescent Cell Burden Alleviates Focal Radiotherapy‐Related Bone Loss

Journal of bone and mineral research, 2020-06, Vol.35 (6), p.1119-1131

2020

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Bone Marrow Adiposity in Models of Radiation‐ and Aging‐Related Bone Loss Is Dependent on Cellular Senescence

Journal of bone and mineral research, 2022-05, Vol.37 (5), p.997-1011

2022

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Isolation and characterization of bone mesenchymal cell small extracellular vesicles using a novel mouse model

Journal of bone and mineral research, 2024-08

2024

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Identification of a suitable endogenous control miRNA in bone aging and senescence

Gene, 2022-08, Vol.835, p.146642-146642, Article 146642

2022

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miR‐219a‐5p Regulates Rorβ During Osteoblast Differentiation and in Age‐related Bone Loss

Journal of bone and mineral research, 2019-01, Vol.34 (1), p.135-144

2019

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Skeletal Effects of Inducible ERα Deletion in Osteocytes in Adult Mice

Journal of bone and mineral research, 2022-09, Vol.37 (9), p.1750-1760

2022

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Effects of intermittent senolytic therapy on bone metabolism in postmenopausal women: a phase 2 randomized controlled trial

Nature medicine, 2024-07, Vol.30 (9), p.2605-2612

2024

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Retinoblastoma binding protein-1 (RBP1) is a Runx2 coactivator and promotes osteoblastic differentiation

BMC musculoskeletal disorders, 2010-05, Vol.11 (1), p.104-104, Article 104

2010

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Osteoprotection Through the Deletion of the Transcription Factor Rorβ in Mice

Journal of bone and mineral research, 2018-04, Vol.33 (4), p.720-731

2018

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Identification of Rorβ targets in cultured osteoblasts and in human bone

Biochemical and biophysical research communications, 2013-11, Vol.440 (4), p.768-773

2013

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Deletion of Estrogen Receptor Beta in Osteoprogenitor Cells Increases Trabecular but Not Cortical Bone Mass in Female Mice

Journal of bone and mineral research, 2016-03, Vol.31 (3), p.606-614

2016

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Identification of Senescent Cells in the Bone Microenvironment

Periodontal Disease and Senescent Cells: New Players for an Old Oral Health Problem?

The role of senolytics in osteoporosis and other skeletal pathologies

Effects of Age and Estrogen on Skeletal Gene Expression in Humans as Assessed by RNA Sequencing

Effects of age on bone mRNA levels of sclerostin and other genes relevant to bone metabolism in humans

Calcium mimics the chemotactic effect of conditioned media and is an effective inducer of bone regeneration

Estrogen and the skeleton

Dissection of estrogen receptor alpha signaling pathways in osteoblasts using RNA-sequencing

Global transcriptional profiling using RNA sequencing and DNA methylation patterns in highly enriched mesenchymal cells from young versus elderly women

Targeting cellular senescence prevents age-related bone loss in mice

Update on Wnt signaling in bone cell biology and bone disease

LPS-induced premature osteocyte senescence: Implications in inflammatory alveolar bone loss and periodontal disease pathogenesis

miRNAs in osteoclast biology

Independent Roles of Estrogen Deficiency and Cellular Senescence in the Pathogenesis of Osteoporosis: Evidence in Young Adult Mice and Older Humans

Targeted Reduction of Senescent Cell Burden Alleviates Focal Radiotherapy‐Related Bone Loss

Bone Marrow Adiposity in Models of Radiation‐ and Aging‐Related Bone Loss Is Dependent on Cellular Senescence

Isolation and characterization of bone mesenchymal cell small extracellular vesicles using a novel mouse model

Identification of a suitable endogenous control miRNA in bone aging and senescence

miR‐219a‐5p Regulates Rorβ During Osteoblast Differentiation and in Age‐related Bone Loss

Skeletal Effects of Inducible ERα Deletion in Osteocytes in Adult Mice

Effects of intermittent senolytic therapy on bone metabolism in postmenopausal women: a phase 2 randomized controlled trial

Retinoblastoma binding protein-1 (RBP1) is a Runx2 coactivator and promotes osteoblastic differentiation

Osteoprotection Through the Deletion of the Transcription Factor Rorβ in Mice

Identification of Rorβ targets in cultured osteoblasts and in human bone

Deletion of Estrogen Receptor Beta in Osteoprogenitor Cells Increases Trabecular but Not Cortical Bone Mass in Female Mice

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