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Conditional Peripheral Membrane Proteins: Facing up to Limited Specificity

Structure (London), 2012-01, Vol.20 (1), p.15-27

2012

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ALK Mutations Confer Differential Oncogenic Activation and Sensitivity to ALK Inhibition Therapy in Neuroblastoma

Cancer cell, 2014-11, Vol.26 (5), p.682-694

2014

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EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics

Cell, 2017-10, Vol.171 (3), p.683-695.e18

2017

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Insulin and epidermal growth factor receptor family members share parallel activation mechanisms

Protein science, 2020-06, Vol.29 (6), p.1331-1344

2020

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Complex Relationship between Ligand Binding and Dimerization in the Epidermal Growth Factor Receptor

Cell reports (Cambridge), 2014-11, Vol.9 (4), p.1306-1317

2014

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Structural Basis for Negative Cooperativity in Growth Factor Binding to an EGF Receptor

Cell, 2010-08, Vol.142 (4), p.568-579

2010

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The Juxtamembrane Region of the EGF Receptor Functions as an Activation Domain

Molecular cell, 2009-06, Vol.34 (6), p.641-651

2009

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Dynamin GTPase regulation is altered by PH domain mutations found in centronuclear myopathy patients

The EMBO journal, 2010-09, Vol.29 (18), p.3054-3067

2010

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TIPE3 Is the Transfer Protein of Lipid Second Messengers that Promote Cancer

Cancer cell, 2014-10, Vol.26 (4), p.465-478

2014

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Cell Signaling by Receptor Tyrosine Kinases

Cell, 2010-06, Vol.141 (7), p.1117-1134

2010

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Putting together structures of epidermal growth factor receptors

Current opinion in structural biology, 2014-12, Vol.29, p.95-101

2014

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Kinase Associated-1 Domains Drive MARK/PAR1 Kinases to Membrane Targets by Binding Acidic Phospholipids

Cell, 2010-12, Vol.143 (6), p.966-977

2010

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Functional selectivity of EGF family peptide growth factors: implications for cancer

Pharmacology & therapeutics (Oxford), 2009-04, Vol.122 (1), p.1-8

2009

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Comparison of Saccharomyces cerevisiae F-BAR Domain Structures Reveals a Conserved Inositol Phosphate Binding Site

Structure (London), 2015-02, Vol.23 (2), p.352-363

2015

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Structural Basis for MARK1 Kinase Autoinhibition by Its KA1 Domain

Structure (London), 2018-08, Vol.26 (8), p.1137-1143.e3

2018

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Identification of the Rac-GEF P-Rex1 as an Essential Mediator of ErbB Signaling in Breast Cancer

Molecular cell, 2010-12, Vol.40 (6), p.877-892

2010

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Determining selectivity of phosphoinositide-binding domains

Methods (San Diego, Calif.), 2006-06, Vol.39 (2), p.122-133

2006

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Distinct interactions stabilize EGFR dimers and higher-order oligomers in cell membranes

Cell reports (Cambridge), 2024-01, Vol.43 (1), p.113603-113603, Article 113603

2024

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Mutations in or near the transmembrane domain alter PMEL amyloid formation from functional to pathogenic

PLoS genetics, 2011-09, Vol.7 (9), p.e1002286-e1002286

2011

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ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes

Cell reports (Cambridge), 2021-10, Vol.37 (3), p.109834-109834, Article 109834

2021

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Ligand-induced ErbB receptor dimerization

Experimental cell research, 2009-02, Vol.315 (4), p.638-648

Lemmon, Mark A.

2009

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Ligand-Induced Structural Transitions in ErbB Receptor Extracellular Domains

Structure (London), 2007-08, Vol.15 (8), p.942-954

2007

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Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors

The EMBO journal, 2004-05, Vol.23 (9), p.1922-1933

2004

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Pleckstrin homology domains and the cytoskeleton

FEBS Letters, 2002-02, Vol.513 (1), p.71-76

2002

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Looking lively: emerging principles of pseudokinase signaling

Trends in biochemical sciences (Amsterdam. Regular ed.), 2022-10, Vol.47 (10), p.875-891

2022

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Conditional Peripheral Membrane Proteins: Facing up to Limited Specificity

ALK Mutations Confer Differential Oncogenic Activation and Sensitivity to ALK Inhibition Therapy in Neuroblastoma

EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics

Insulin and epidermal growth factor receptor family members share parallel activation mechanisms

Complex Relationship between Ligand Binding and Dimerization in the Epidermal Growth Factor Receptor

Structural Basis for Negative Cooperativity in Growth Factor Binding to an EGF Receptor

The Juxtamembrane Region of the EGF Receptor Functions as an Activation Domain

Dynamin GTPase regulation is altered by PH domain mutations found in centronuclear myopathy patients

TIPE3 Is the Transfer Protein of Lipid Second Messengers that Promote Cancer

Cell Signaling by Receptor Tyrosine Kinases

Putting together structures of epidermal growth factor receptors

Kinase Associated-1 Domains Drive MARK/PAR1 Kinases to Membrane Targets by Binding Acidic Phospholipids

Functional selectivity of EGF family peptide growth factors: implications for cancer

Comparison of Saccharomyces cerevisiae F-BAR Domain Structures Reveals a Conserved Inositol Phosphate Binding Site

Structural Basis for MARK1 Kinase Autoinhibition by Its KA1 Domain

Identification of the Rac-GEF P-Rex1 as an Essential Mediator of ErbB Signaling in Breast Cancer

Determining selectivity of phosphoinositide-binding domains

Distinct interactions stabilize EGFR dimers and higher-order oligomers in cell membranes

Mutations in or near the transmembrane domain alter PMEL amyloid formation from functional to pathogenic

ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes

Ligand-induced ErbB receptor dimerization

Ligand-Induced Structural Transitions in ErbB Receptor Extracellular Domains

Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors

Pleckstrin homology domains and the cytoskeleton

Looking lively: emerging principles of pseudokinase signaling

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