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Approaching tumour therapy beyond platinum drugs: status of the art and perspectives of ruthenium drug candidates

Journal of inorganic biochemistry, 2012-01, Vol.106 (1), p.90-99

2012

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Inventory of oral anticancer agents: pharmaceutical formulation aspects with focus on the solid dispersion technique

Cancer treatment reviews, 2016-11, Vol.50, p.247-263

2016

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Increased Oral Bioavailability of Topotecan in Combination With the Breast Cancer Resistance Protein and P-Glycoprotein Inhibitor GF120918

Journal of clinical oncology, 2002-07, Vol.20 (13), p.2943-2950

2002

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Volumetric absorptive microsampling (VAMS) as an alternative to conventional dried blood spots in the quantification of miltefosine in dried blood samples

Journal of pharmaceutical and biomedical analysis, 2017-02, Vol.135, p.160-166

2017

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Exposure–response analyses of BRAF- and MEK-inhibitors dabrafenib plus trametinib in melanoma patients

Cancer chemotherapy and pharmacology, 2023-06, Vol.91 (6), p.447-456

2023

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Bioanalysis of ibrutinib, and its dihydrodiol- and glutathione cycle metabolites by liquid chromatography-tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2018-07, Vol.1090, p.14-21

2018

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Development and validation of an integrated LC-MS/MS assay for therapeutic drug monitoring of five PARP-inhibitors

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020-02, Vol.1138, p.121925-121925, Article 121925

2020

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Validation and clinical application of an LC-MS/MS method for the quantification of everolimus using volumetric absorptive microsampling

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2019-01, Vol.1104, p.234-239

2019

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Bioanalysis of EGFRm inhibitor osimertinib, and its glutathione cycle- and desmethyl metabolites by liquid chromatography-tandem mass spectrometry

Journal of pharmaceutical and biomedical analysis, 2020-01, Vol.177, p.112871, Article 112871

2020

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A real or apparent decrease in glomerular filtration rate in patients using olaparib?

European journal of clinical pharmacology, 2021-02, Vol.77 (2), p.179-188

2021

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Quantification of protease inhibitors and non-nucleoside reverse transcriptase inhibitors in dried blood spots by liquid chromatography–triple quadrupole mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008-05, Vol.867 (2), p.205-212

2008

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Effects of cytochrome P450 3A (CYP3A) and the drug transporters P‐glycoprotein (MDR1/ABCB1) and MRP2 (ABCC2) on the pharmacokinetics of lopinavir

British journal of pharmacology, 2010-07, Vol.160 (5), p.1224-1233

2010

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Pharmaceutical development and preliminary clinical testing of an oral solid dispersion formulation of docetaxel (ModraDoc001)

International journal of pharmaceutics, 2011-11, Vol.420 (2), p.244-250

2011

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Development of a UPLC-MS/MS Assay for the Quantitative Determination of Capecitabine, 5'-deoxy-5-fluorocytidine (5'-dFCR), 5'-deoxy-5-fluorouridine (5'-dFUR), 5'-fluorouracil (5-FU), and α-fluoro-β-alanine (FBAL)

Pharmazie, 2023-08, Vol.78 (8), p.107-112

2023

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Development and validation of an UPLC-MS/MS method for the therapeutic drug monitoring of oral anti-hormonal drugs in oncology

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2019-02, Vol.1106-1107, p.26-34

2019

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A highly sensitive bioanalytical method for the quantification of vinblastine, vincristine, vinorelbine and 4-O-deacetylvinorelbine in human plasma using LC-MS/MS

Journal of pharmaceutical and biomedical analysis, 2022-06, Vol.215, p.114772-114772, Article 114772

2022

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The development and validation of a high performance liquid chromatography method to determine the radiochemical purity of [177Lu]Lu-HA-DOTA-TATE in pharmaceutical preparations

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2021-05, Vol.1171, p.122605-122605, Article 122605

2021

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Stability of oxaliplatin in chloride-containing carrier solutions used in hyperthermic intraperitoneal chemotherapy

International journal of pharmaceutics, 2015-02, Vol.479 (1), p.23-27

2015

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Tandem mass spectrometry of small-molecule signal transduction inhibitors: Accurate-m/z data to adapt structure proposals of product ions

Journal of pharmaceutical and biomedical analysis, 2021-02, Vol.195, p.113864-113864, Article 113864

2021

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Exposure-survival analyses of pazopanib in renal cell carcinoma and soft tissue sarcoma patients: opportunities for dose optimization

Cancer chemotherapy and pharmacology, 2017-12, Vol.80 (6), p.1171-1178

2017

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Inherent formulation issues of kinase inhibitors

Journal of controlled release, 2016-10, Vol.239, p.118-127

2016

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PXR-mediated induction of P-glycoprotein by anticancer drugs in a human colon adenocarcinoma-derived cell line

Cancer chemotherapy and pharmacology, 2010-09, Vol.66 (4), p.765-771

2010

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Effect of Chinese herbs on CYP3A4 activity and expression in vitro

Journal of ethnopharmacology, 2013-09, Vol.149 (2), p.543-549

2013

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Development and validation of a UPLC-MS/MS method with a broad linear dynamic range for the quantification of morphine, morphine-3-glucuronide and morphine-6-glucuronide in mouse plasma and tissue homogenates

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2021-03, Vol.1166, p.122403-122403, Article 122403

2021

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Nuclear receptor mediated induction of cytochrome P450 3A4 by anticancer drugs: a key role for the pregnane X receptor

Cancer chemotherapy and pharmacology, 2009-06, Vol.64 (1), p.35-43

2009

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Approaching tumour therapy beyond platinum drugs: status of the art and perspectives of ruthenium drug candidates

Inventory of oral anticancer agents: pharmaceutical formulation aspects with focus on the solid dispersion technique

Increased Oral Bioavailability of Topotecan in Combination With the Breast Cancer Resistance Protein and P-Glycoprotein Inhibitor GF120918

Volumetric absorptive microsampling (VAMS) as an alternative to conventional dried blood spots in the quantification of miltefosine in dried blood samples

Exposure–response analyses of BRAF- and MEK-inhibitors dabrafenib plus trametinib in melanoma patients

Bioanalysis of ibrutinib, and its dihydrodiol- and glutathione cycle metabolites by liquid chromatography-tandem mass spectrometry

Development and validation of an integrated LC-MS/MS assay for therapeutic drug monitoring of five PARP-inhibitors

Validation and clinical application of an LC-MS/MS method for the quantification of everolimus using volumetric absorptive microsampling

Bioanalysis of EGFRm inhibitor osimertinib, and its glutathione cycle- and desmethyl metabolites by liquid chromatography-tandem mass spectrometry

A real or apparent decrease in glomerular filtration rate in patients using olaparib?

Quantification of protease inhibitors and non-nucleoside reverse transcriptase inhibitors in dried blood spots by liquid chromatography–triple quadrupole mass spectrometry

Effects of cytochrome P450 3A (CYP3A) and the drug transporters P‐glycoprotein (MDR1/ABCB1) and MRP2 (ABCC2) on the pharmacokinetics of lopinavir

Pharmaceutical development and preliminary clinical testing of an oral solid dispersion formulation of docetaxel (ModraDoc001)

Development of a UPLC-MS/MS Assay for the Quantitative Determination of Capecitabine, 5'-deoxy-5-fluorocytidine (5'-dFCR), 5'-deoxy-5-fluorouridine (5'-dFUR), 5'-fluorouracil (5-FU), and α-fluoro-β-alanine (FBAL)

Development and validation of an UPLC-MS/MS method for the therapeutic drug monitoring of oral anti-hormonal drugs in oncology

A highly sensitive bioanalytical method for the quantification of vinblastine, vincristine, vinorelbine and 4-O-deacetylvinorelbine in human plasma using LC-MS/MS

The development and validation of a high performance liquid chromatography method to determine the radiochemical purity of [177Lu]Lu-HA-DOTA-TATE in pharmaceutical preparations

Stability of oxaliplatin in chloride-containing carrier solutions used in hyperthermic intraperitoneal chemotherapy

Tandem mass spectrometry of small-molecule signal transduction inhibitors: Accurate-m/z data to adapt structure proposals of product ions

Exposure-survival analyses of pazopanib in renal cell carcinoma and soft tissue sarcoma patients: opportunities for dose optimization

Inherent formulation issues of kinase inhibitors

PXR-mediated induction of P-glycoprotein by anticancer drugs in a human colon adenocarcinoma-derived cell line

Effect of Chinese herbs on CYP3A4 activity and expression in vitro

Development and validation of a UPLC-MS/MS method with a broad linear dynamic range for the quantification of morphine, morphine-3-glucuronide and morphine-6-glucuronide in mouse plasma and tissue homogenates

Nuclear receptor mediated induction of cytochrome P450 3A4 by anticancer drugs: a key role for the pregnane X receptor

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