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NLCQ-1 and NLCQ-2, two new agents with activity against dormant Mycobacterium tuberculosis

International journal of antimicrobial agents, 2007-06, Vol.29 (6), p.724-727

2007

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The gastrointestinal effects that may follow the administration of theophylline reflect the pharmacodynamic profiles of both the parent drug and its metabolites

Fundamental & clinical pharmacology, 2010-04, Vol.24 (2), p.171-180

2010

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Concomitant loss of dynorphin, NARP, and orexin in narcolepsy

Neurology, 2005-10, Vol.65 (8), p.1184-1188

2005

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Synthesis of a novel nitroimidazole-spermidine derivative as a tumor-targeted hypoxia-selective cytotoxin

Bioorganic & medicinal chemistry letters, 2004-03, Vol.14 (6), p.1519-1522

2004

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Relaxing and contracting effects of theophylline's metabolites on the rabbit upper gastrointestinal tract

Fundamental & clinical pharmacology, 2008-10, Vol.22 (5), p.537-547

2008

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Schedule-dependent potentiation of chemotherapeutic drugs by the bioreductive compounds NLCQ-1 and tirapazamine against EMT6 tumors in mice

Cancer chemotherapy and pharmacology, 2001-08, Vol.48 (2), p.160-168

2001

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Synthesis of novel 2-nitroimidazole-tethered tricyclic quinolines, bearing a second heteroatom, and their in vitro evaluation as hypoxia-selective cytotoxins and radiosensitizers

Bioorganic & medicinal chemistry letters, 2004-03, Vol.14 (6), p.1523-1525

2004

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Reductive metabolism of the nitroimidazole-based hypoxia-selective cytotoxin NLCQ-1 (NSC 709257)

Oncology research, 2003, Vol.14 (1), p.21-29

2003

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NLCQ-1, a novel hypoxic cytotoxin: potentiation of melphalan, cisDDP and cyclophosphamide in vivo

International journal of radiation oncology, biology, physics, 1998-11, Vol.42 (4), p.775-779

1998

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4-[3-(2-Nitro-1-imidazolyl)propylamino]-7-chloroquinoline hydrochloride (NLCQ-1), a novel bioreductive compound as a hypoxia-selective cytotoxin

Oncology research, 2000-01, Vol.12 (4), p.185-192

2000

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Application and validation of a LC/fluorescence method for the determination of amoxicillin in sheep serum and tissue cage fluid

Journal of pharmaceutical and biomedical analysis, 2009-02, Vol.49 (2), p.375-380

2009

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4-[3-(2-Nitro-1-imidazolyl)propylamino]-7-chloroquinoline hydrochloride (NLCQ-1), a novel bioreductive agent as radiosensitizer in vitro and in vivo: comparison with tirapazamine

Oncology research, 2001-08, Vol.12 (8), p.325-333

2001

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Synergistic enhancement of the antitumor effect of taxol by the bioreductive compound NLCQ-1, in vivo: comparison with tirapazamine

Oncology research, 2002, Vol.13 (1), p.47-54

2002

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Therapeutic advantage from combining paclitaxel with the hypoxia-selective cytotoxin NLCQ-1 in murine tumor- or human xenograft-bearing mice

Cancer chemotherapy and pharmacology, 2002-12, Vol.50 (6), p.501-508

2002

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Optic Nerve Hypoplasia and Growth Hormone Deficiency in a Cholestatic Infant

Pediatric neurology, 2006-04, Vol.34 (4), p.319-322

2006

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Interaction of strong DNA-intercalating bioreductive compounds with topoisomerases I and II

Oncology research, 2005-01, Vol.15 (4), p.219-231

2005

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9-[3-(2-Nitro-1-imidazolyl)propylamino]-cyclopenteno[b]quinoline hydrochloride (NLCPQ-1). A novel DNA-affinic bioreductive agent as chemosensitizer: mechanistic studies. II

Oncology research, 1998, Vol.10 (3), p.163

1998

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9-[3-(2-Nitro-1-imidazolyl)propylamino]-cyclopenteno[b]quinoline hydrochloride (NLCPQ-1). A novel DNA-affinic bioreductive agent as cytotoxin and radiosensitizer

Oncology research, 1996, Vol.8 (10-11), p.425

1996

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9-[3-(2-Nitro-1-imidazolyl)propylamino]-1,2,3,4-tetrahydroacridine hydrochloride. A novel DNA-affinic hypoxic cell cytotoxin and radiosensitizer. Comparison with NLA-1

Oncology research, 1994, Vol.6 (9), p.439

1994

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9-[3-(2-Nitro-1-imidazolyl)propylamino]-cyclopenteno[b]quinoline hydrochloride (NLCPQ-1): a novel DNA-affinic bioreductive agent as chemosensitizer. I

Oncology research, 1997, Vol.9 (5), p.249

1997

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2-Alkylsulfonyloxy-3-hydroxy-1,4-naphthoquinones: a novel class of radio- and chemosensitizers of V79 cells

Oncology research, 1993, Vol.5 (1), p.29

1993

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Boosting chaperone-mediated autophagy in vivo mitigates α-synuclein-induced neurodegeneration

Brain (London, England : 1878), 2013-07, Vol.136 (Pt 7), p.2130-2146

2013

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Early maternal deprivation-induced modifications in the neurobiological, neurochemical and behavioral profile of adult rats

Behavioural brain research, 2013-05, Vol.244, p.29-37

2013

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Enzymatic hybridization of α-lipoic acid with bioactive compounds in ionic solvents

Bioresource technology, 2013-05, Vol.136, p.41-48

2013

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Bipolar I and bipolar II disorder: cognition and emotion processing

Psychological medicine, 2006-12, Vol.36 (12), p.1799-1809

2006

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NLCQ-1 and NLCQ-2, two new agents with activity against dormant Mycobacterium tuberculosis

The gastrointestinal effects that may follow the administration of theophylline reflect the pharmacodynamic profiles of both the parent drug and its metabolites

Concomitant loss of dynorphin, NARP, and orexin in narcolepsy

Synthesis of a novel nitroimidazole-spermidine derivative as a tumor-targeted hypoxia-selective cytotoxin

Relaxing and contracting effects of theophylline's metabolites on the rabbit upper gastrointestinal tract

Schedule-dependent potentiation of chemotherapeutic drugs by the bioreductive compounds NLCQ-1 and tirapazamine against EMT6 tumors in mice

Synthesis of novel 2-nitroimidazole-tethered tricyclic quinolines, bearing a second heteroatom, and their in vitro evaluation as hypoxia-selective cytotoxins and radiosensitizers

Reductive metabolism of the nitroimidazole-based hypoxia-selective cytotoxin NLCQ-1 (NSC 709257)

NLCQ-1, a novel hypoxic cytotoxin: potentiation of melphalan, cisDDP and cyclophosphamide in vivo

4-[3-(2-Nitro-1-imidazolyl)propylamino]-7-chloroquinoline hydrochloride (NLCQ-1), a novel bioreductive compound as a hypoxia-selective cytotoxin

Application and validation of a LC/fluorescence method for the determination of amoxicillin in sheep serum and tissue cage fluid

4-[3-(2-Nitro-1-imidazolyl)propylamino]-7-chloroquinoline hydrochloride (NLCQ-1), a novel bioreductive agent as radiosensitizer in vitro and in vivo: comparison with tirapazamine

Synergistic enhancement of the antitumor effect of taxol by the bioreductive compound NLCQ-1, in vivo: comparison with tirapazamine

Therapeutic advantage from combining paclitaxel with the hypoxia-selective cytotoxin NLCQ-1 in murine tumor- or human xenograft-bearing mice

Optic Nerve Hypoplasia and Growth Hormone Deficiency in a Cholestatic Infant

Interaction of strong DNA-intercalating bioreductive compounds with topoisomerases I and II

9-[3-(2-Nitro-1-imidazolyl)propylamino]-cyclopenteno[b]quinoline hydrochloride (NLCPQ-1). A novel DNA-affinic bioreductive agent as chemosensitizer: mechanistic studies. II

9-[3-(2-Nitro-1-imidazolyl)propylamino]-cyclopenteno[b]quinoline hydrochloride (NLCPQ-1). A novel DNA-affinic bioreductive agent as cytotoxin and radiosensitizer

9-[3-(2-Nitro-1-imidazolyl)propylamino]-1,2,3,4-tetrahydroacridine hydrochloride. A novel DNA-affinic hypoxic cell cytotoxin and radiosensitizer. Comparison with NLA-1

9-[3-(2-Nitro-1-imidazolyl)propylamino]-cyclopenteno[b]quinoline hydrochloride (NLCPQ-1): a novel DNA-affinic bioreductive agent as chemosensitizer. I

2-Alkylsulfonyloxy-3-hydroxy-1,4-naphthoquinones: a novel class of radio- and chemosensitizers of V79 cells

Boosting chaperone-mediated autophagy in vivo mitigates α-synuclein-induced neurodegeneration

Early maternal deprivation-induced modifications in the neurobiological, neurochemical and behavioral profile of adult rats

Enzymatic hybridization of α-lipoic acid with bioactive compounds in ionic solvents

Bipolar I and bipolar II disorder: cognition and emotion processing

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