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Metabolic stress in insulin’s target cells leads to ROS accumulation – A hypothetical common pathway causing insulin resistance

FEBS letters, 2007-07, Vol.581 (19), p.3734-3742

Eriksson, Jan W.

2007

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Fatty acid profile of the erythrocyte membrane preceding development of Type 2 diabetes mellitus

Nutrition, metabolism, and cardiovascular diseases, 2008-09, Vol.18 (7), p.503-510

2008

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Novel pancreatic beta cell-specific proteins: Antibody-based proteomics for identification of new biomarker candidates

Journal of proteomics, 2012-05, Vol.75 (9), p.2611-2620

2012

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Microdialysis and proteomics of subcutaneous interstitial fluid reveals increased galectin-1 in type 2 diabetes patients

Metabolism, clinical and experimental, 2016-07, Vol.65 (7), p.998-1006

2016

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Effects of free omega-3 carboxylic acids and fenofibrate on liver fat content in patients with hypertriglyceridemia and non-alcoholic fatty liver disease: A double-blind, randomized, placebo-controlled study

Journal of clinical lipidology, 2018-11, Vol.12 (6), p.1390-1403.e4

2018

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Direct effects of glucagon on glucose uptake and lipolysis in human adipocytes

Molecular and cellular endocrinology, 2020-03, Vol.503, p.110696, Article 110696

2020

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Sulphonylurea compared to DPP-4 inhibitors in combination with metformin carries increased risk of severe hypoglycemia, cardiovascular events, and all-cause mortality

Diabetes research and clinical practice, 2016-07, Vol.117, p.39-47

2016

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Estrogen interacts with glucocorticoids in the regulation of lipocalin 2 expression in human adipose tissue. Reciprocal roles of estrogen receptor α and β in insulin resistance?

Molecular and cellular endocrinology, 2019-06, Vol.490, p.28-36

2019

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Interleukin-33 inhibits glucose uptake in human adipocytes and its expression in adipose tissue is elevated in insulin resistance and type 2 diabetes

Cytokine (Philadelphia, Pa.), 2023-01, Vol.161, p.156080-156080, Article 156080

2023

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Modulation of hypothalamic AMPK phosphorylation by olanzapine controls energy balance and body weight

Metabolism, clinical and experimental, 2022-12, Vol.137, p.155335-155335, Article 155335

2022

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Human macrophages stimulate expression of inflammatory mediators in adipocytes; effects of second-generation antipsychotics and glucocorticoids on cellular cross-talk

Psychoneuroendocrinology, 2021-03, Vol.125, p.105071-105071, Article 105071

2021

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Effects of the second-generation antipsychotic drugs aripiprazole and olanzapine on human adipocyte differentiation

Molecular and cellular endocrinology, 2023-02, Vol.561, p.111828, Article 111828

2023

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Insulin resistance induced by high glucose and high insulin precedes insulin receptor substrate 1 protein depletion in human adipocytes

Metabolism, clinical and experimental, 2007-02, Vol.56 (2), p.190-198

2007

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Excess glucocorticoid exposure contributes to adipose tissue fibrosis which involves macrophage interaction with adipose precursor cells

Biochemical pharmacology, 2022-04, Vol.198, p.114976-114976, Article 114976

2022

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Effects of second-generation antipsychotics on human subcutaneous adipose tissue metabolism

Psychoneuroendocrinology, 2019-12, Vol.110, p.104445-104445, Article 104445

2019

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Second line initiation of insulin compared with DPP-4 inhibitors after metformin monotherapy is associated with increased risk of all-cause mortality, cardiovascular events, and severe hypoglycemia

Diabetes research and clinical practice, 2017-01, Vol.123, p.199-208

2017

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Impaired adipose tissue lipid storage, but not altered lipolysis, contributes to elevated levels of NEFA in type 2 diabetes. Degree of hyperglycemia and adiposity are important factors

Metabolism, clinical and experimental, 2016-12, Vol.65 (12), p.1768-1780

2016

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FKBP5 expression in human adipose tissue increases following dexamethasone exposure and is associated with insulin resistance

Metabolism, clinical and experimental, 2014-09, Vol.63 (9), p.1198-1208

2014

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CDKN2C expression in adipose tissue is reduced in type II diabetes and central obesity: impact on adipocyte differentiation and lipid storage?

Translational research : the journal of laboratory and clinical medicine, 2022-04, Vol.242, p.105-121

2022

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Patient-reported outcomes and visual acuity after 12 months of anti-VEGF-treatment for sight-threatening diabetic macular edema in a real world setting

Diabetes research and clinical practice, 2016-11, Vol.121, p.157-165

2016

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The immunosuppressive agents rapamycin, cyclosporin A and tacrolimus increase lipolysis, inhibit lipid storage and alter expression of genes involved in lipid metabolism in human adipose tissue

Molecular and cellular endocrinology, 2013-01, Vol.365 (2), p.260-269

2013

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A registry-based randomised trial comparing an SGLT2 inhibitor and metformin as standard treatment of early stage type 2 diabetes (SMARTEST): Rationale, design and protocol

Journal of diabetes and its complications, 2021-10, Vol.35 (10), p.107996-107996, Article 107996

2021

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Insulin action and signalling in fat and muscle from dexamethasone-treated rats

Archives of biochemistry and biophysics, 2008-06, Vol.474 (1), p.91-101

2008

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mTOR inhibition with rapamycin causes impaired insulin signalling and glucose uptake in human subcutaneous and omental adipocytes

Molecular and cellular endocrinology, 2012-05, Vol.355 (1), p.96-105

2012

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Postprandial regulation of blood lipids and adipose tissue lipoprotein lipase in type 2 diabetes patients and healthy control subjects

Atherosclerosis, 2003-02, Vol.166 (2), p.359-367

2003

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Metabolic stress in insulin’s target cells leads to ROS accumulation – A hypothetical common pathway causing insulin resistance

Fatty acid profile of the erythrocyte membrane preceding development of Type 2 diabetes mellitus

Novel pancreatic beta cell-specific proteins: Antibody-based proteomics for identification of new biomarker candidates

Microdialysis and proteomics of subcutaneous interstitial fluid reveals increased galectin-1 in type 2 diabetes patients

Effects of free omega-3 carboxylic acids and fenofibrate on liver fat content in patients with hypertriglyceridemia and non-alcoholic fatty liver disease: A double-blind, randomized, placebo-controlled study

Direct effects of glucagon on glucose uptake and lipolysis in human adipocytes

Sulphonylurea compared to DPP-4 inhibitors in combination with metformin carries increased risk of severe hypoglycemia, cardiovascular events, and all-cause mortality

Estrogen interacts with glucocorticoids in the regulation of lipocalin 2 expression in human adipose tissue. Reciprocal roles of estrogen receptor α and β in insulin resistance?

Interleukin-33 inhibits glucose uptake in human adipocytes and its expression in adipose tissue is elevated in insulin resistance and type 2 diabetes

Modulation of hypothalamic AMPK phosphorylation by olanzapine controls energy balance and body weight

Human macrophages stimulate expression of inflammatory mediators in adipocytes; effects of second-generation antipsychotics and glucocorticoids on cellular cross-talk

Effects of the second-generation antipsychotic drugs aripiprazole and olanzapine on human adipocyte differentiation

Insulin resistance induced by high glucose and high insulin precedes insulin receptor substrate 1 protein depletion in human adipocytes

Excess glucocorticoid exposure contributes to adipose tissue fibrosis which involves macrophage interaction with adipose precursor cells

Effects of second-generation antipsychotics on human subcutaneous adipose tissue metabolism

Second line initiation of insulin compared with DPP-4 inhibitors after metformin monotherapy is associated with increased risk of all-cause mortality, cardiovascular events, and severe hypoglycemia

Impaired adipose tissue lipid storage, but not altered lipolysis, contributes to elevated levels of NEFA in type 2 diabetes. Degree of hyperglycemia and adiposity are important factors

FKBP5 expression in human adipose tissue increases following dexamethasone exposure and is associated with insulin resistance

CDKN2C expression in adipose tissue is reduced in type II diabetes and central obesity: impact on adipocyte differentiation and lipid storage?

Patient-reported outcomes and visual acuity after 12 months of anti-VEGF-treatment for sight-threatening diabetic macular edema in a real world setting

The immunosuppressive agents rapamycin, cyclosporin A and tacrolimus increase lipolysis, inhibit lipid storage and alter expression of genes involved in lipid metabolism in human adipose tissue

A registry-based randomised trial comparing an SGLT2 inhibitor and metformin as standard treatment of early stage type 2 diabetes (SMARTEST): Rationale, design and protocol

Insulin action and signalling in fat and muscle from dexamethasone-treated rats

mTOR inhibition with rapamycin causes impaired insulin signalling and glucose uptake in human subcutaneous and omental adipocytes

Postprandial regulation of blood lipids and adipose tissue lipoprotein lipase in type 2 diabetes patients and healthy control subjects

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