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Characterization of metabolites and cytochrome P450 isoforms involved in the microsomal metabolism of aconitine

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006-12, Vol.844 (2), p.292-300

2006

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Inhibitory effects of a dietary phytochemical 3,3′-diindolylmethane on the phenobarbital-induced hepatic CYP mRNA expression and CYP-catalyzed reactions in female rats

Food and chemical toxicology, 2008-07, Vol.46 (7), p.2451-2458

2008

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A mechanism-based integrated pharmacokinetic enzyme model describing the time course and magnitude of phenobarbital-mediated enzyme induction in the rat

Pharmaceutical research, 2006-03, Vol.23 (3), p.521-532

2006

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The Role of Cytochrome 2B1 Substrate Recognition Site Residues 115, 294, 297, 298, and 362 in the Oxidation of Steroids and 7-Alkoxycoumarins

Archives of biochemistry and biophysics, 2001-10, Vol.394 (1), p.21-28

2001

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Induction of CYP2B1/2 and nicotine metabolism by ethanol in rat liver but not rat brain

Biochemical pharmacology, 2001-10, Vol.62 (8), p.1025-1036

2001

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Effect of naturally occurring plant phenolics on the induction of drug metabolizing enzymes by o-toluidine

Toxicology (Amsterdam), 2003-04, Vol.186 (1), p.67-77

2003

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In vitro metabolism and covalent binding of ethylbenzene to microsomal protein as a possible mechanism of ethylbenzene-induced mouse lung tumorigenesis

Regulatory toxicology and pharmacology, 2010-07, Vol.57 (2-3), p.129-135

2010

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Overexpression of cerebral and hepatic cytochrome P450s alters behavioral activity of rat offspring following prenatal exposure to lindane

Toxicology and applied pharmacology, 2007-12, Vol.225 (3), p.278-292

2007

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Role of the Alanine at Position 363 of Cytochrome P450 2B2 in Influencing the NADPH- and Hydroperoxide-Supported Activities

Archives of biochemistry and biophysics, 1998-02, Vol.350 (2), p.324-332

1998

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Suppression of the Expression of the CYP2B1/2 Gene by Retinoic Acids

Biochemical and biophysical research communications, 2000-10, Vol.277 (1), p.66-71

2000

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Hepatic CYP1A, 2B, 2C, 2E and 3A regulation by methoxychlor in male and female rats

Toxicology letters, 2003-09, Vol.144 (1), p.93-103

2003

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Proteolytic Degradation of Heme-Modified Hepatic Cytochromes P450: A Role for Phosphorylation, Ubiquitination, and the 26S Proteasome?

Archives of biochemistry and biophysics, 1999-05, Vol.365 (1), p.31-44

1999

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In vitro inhibition of liver monooxygenases by β-ionone, 1,8-cineole, (−)-menthol and terpineol

Toxicology (Amsterdam), 1999-07, Vol.135 (1), p.33-41

1999

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Liver subcellular fractions from rats treated by organosulfur compounds from Allium modulate mutagen activation

Mutation research, 2000-03, Vol.466 (1), p.17-26

2000

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Beetroot juice protects against N-nitrosodiethylamine-induced liver injury in rats

Food and chemical toxicology, 2012-06, Vol.50 (6), p.2027-2033

2012

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The spectrum of enzymes involved in activation of 2-aminoanthracene varies with the metabolic system applied

Mutation research, 2005-09, Vol.586 (1), p.18-27

2005

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The immature rat as a potential model for chemical risks to children: Ontogeny of selected hepatic P450s

Chemico-biological interactions, 2016-08, Vol.256, p.167-177

2016

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The contribution of cytochrome P-450 isoenzymes to the metabolism of phenothiazine neuroleptics

European neuropsychopharmacology, 2002-10, Vol.12 (5), p.371-377

2002

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Effect of natamycin on cytochrome P450 enzymes in rats

Food and chemical toxicology, 2013-12, Vol.62, p.281-284

2013

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Molecular non-genetic biomarkers of effect related to methyl thiophanate cocarcinogenesis: organ- and sex-specific cytochrome P450 induction in the rat

Cancer letters, 1999-01, Vol.135 (2), p.203-213

1999

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Inhibition of cytochrome P450 isozymes by curcumins in vitro and in vivo

Food and chemical toxicology, 2001-06, Vol.39 (6), p.541-547

2001

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New proteins in the rat CYP2B subfamily: Presence in liver microsomes of the constitutive CYP2B3 protein and the phenobarbital-inducible protein product of alternatively spliced CYP2B2 mRNA

Biochemical pharmacology, 1996-10, Vol.52 (8), p.1311-1319

1996

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Negative Regulation by Dexamethasone of Fluvastatin-Inducible CYP2B Expression in Primary Cultures of Rat Hepatocytes: Role of CYP3A

Biochemical pharmacology, 1998-05, Vol.55 (9), p.1435-1443

1998

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Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver

Biochemical pharmacology, 1994-08, Vol.48 (5), p.923-936

1994

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Dose-response effects of lycopene on selected drug-metabolizing and antioxidant enzymes in the rat

Cancer letters, 2000-06, Vol.154 (2), p.201-210

2000

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Characterization of metabolites and cytochrome P450 isoforms involved in the microsomal metabolism of aconitine

Inhibitory effects of a dietary phytochemical 3,3′-diindolylmethane on the phenobarbital-induced hepatic CYP mRNA expression and CYP-catalyzed reactions in female rats

A mechanism-based integrated pharmacokinetic enzyme model describing the time course and magnitude of phenobarbital-mediated enzyme induction in the rat

The Role of Cytochrome 2B1 Substrate Recognition Site Residues 115, 294, 297, 298, and 362 in the Oxidation of Steroids and 7-Alkoxycoumarins

Induction of CYP2B1/2 and nicotine metabolism by ethanol in rat liver but not rat brain

Effect of naturally occurring plant phenolics on the induction of drug metabolizing enzymes by o-toluidine

In vitro metabolism and covalent binding of ethylbenzene to microsomal protein as a possible mechanism of ethylbenzene-induced mouse lung tumorigenesis

Overexpression of cerebral and hepatic cytochrome P450s alters behavioral activity of rat offspring following prenatal exposure to lindane

Role of the Alanine at Position 363 of Cytochrome P450 2B2 in Influencing the NADPH- and Hydroperoxide-Supported Activities

Suppression of the Expression of the CYP2B1/2 Gene by Retinoic Acids

Hepatic CYP1A, 2B, 2C, 2E and 3A regulation by methoxychlor in male and female rats

Proteolytic Degradation of Heme-Modified Hepatic Cytochromes P450: A Role for Phosphorylation, Ubiquitination, and the 26S Proteasome?

In vitro inhibition of liver monooxygenases by β-ionone, 1,8-cineole, (−)-menthol and terpineol

Liver subcellular fractions from rats treated by organosulfur compounds from Allium modulate mutagen activation

Beetroot juice protects against N-nitrosodiethylamine-induced liver injury in rats

The spectrum of enzymes involved in activation of 2-aminoanthracene varies with the metabolic system applied

The immature rat as a potential model for chemical risks to children: Ontogeny of selected hepatic P450s

The contribution of cytochrome P-450 isoenzymes to the metabolism of phenothiazine neuroleptics

Effect of natamycin on cytochrome P450 enzymes in rats

Molecular non-genetic biomarkers of effect related to methyl thiophanate cocarcinogenesis: organ- and sex-specific cytochrome P450 induction in the rat

Inhibition of cytochrome P450 isozymes by curcumins in vitro and in vivo

New proteins in the rat CYP2B subfamily: Presence in liver microsomes of the constitutive CYP2B3 protein and the phenobarbital-inducible protein product of alternatively spliced CYP2B2 mRNA

Negative Regulation by Dexamethasone of Fluvastatin-Inducible CYP2B Expression in Primary Cultures of Rat Hepatocytes: Role of CYP3A

Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver

Dose-response effects of lycopene on selected drug-metabolizing and antioxidant enzymes in the rat

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