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The genotoxicity potential of luteolin is enhanced by CYP1A1 and CYP1A2 in human lymphoblastoid TK6 cells

Toxicology letters, 2021-06, Vol.344, p.58-68

2021

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The role of CYP 3A4 and 1A1 in amiodarone-induced hepatocellular toxicity

Toxicology letters, 2016-06, Vol.253, p.55-62

2016

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In vivo pharmacokinetic analyses of placental transfer of three drugs of different physicochemical properties in pregnant rats

Reproductive toxicology (Elmsford, N.Y.), 2022-08, Vol.111, p.194-203

2022

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Evaluation of pyrrolizidine alkaloid-induced genotoxicity using metabolically competent TK6 cell lines

Food and chemical toxicology, 2020-11, Vol.145, p.111662-111662, Article 111662

2020

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90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats

Food and chemical toxicology, 2022-02, Vol.160, p.112780, Article 112780

2022

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Interstrain differences in the progression of nonalcoholic steatohepatitis to fibrosis in mice are associated with altered hepatic iron metabolism

The Journal of nutritional biochemistry, 2014-12, Vol.25 (12), p.1235-1242

2014

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Comparison of endpoints relevant to toxicity assessments in 3 generations of CD-1 mice fed irradiated natural and purified ingredient diets with varying soy protein and isoflavone contents

Food and chemical toxicology, 2016-08, Vol.94, p.39-56

2016

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Model-based feedforward and cascade control of hydraulic McKibben muscles

Sensors and actuators. A. Physical., 2018-06, Vol.275, p.88-98

2018

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Disease-related responses induced by cadmium in an in vitro human airway tissue model

Toxicology letters, 2019-03, Vol.303, p.16-27

2019

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In vitro dosimetry analyses for acrolein exposure in normal human lung epithelial cells and human lung cancer cells

Environmental toxicology and pharmacology, 2021-04, Vol.83, p.103576, Article 103576

2021

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Direct cocktail analysis of drug discovery compounds in pooled plasma samples using liquid chromatography–tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2002-02, Vol.767 (2), p.353-362

2002

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Cytotoxicity of 34 FDA approved small-molecule kinase inhibitors in primary rat and human hepatocytes

Toxicology letters, 2018-07, Vol.291, p.138-148

2018

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Assessing the respiratory toxicity of dihydroxyacetone using an in vitro human airway epithelial tissue model

Toxicology in vitro, 2019-09, Vol.59, p.78-86

2019

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Evaluation of a microphysiological human placental barrier model for studying placental drug transfer

Reproductive toxicology (Elmsford, N.Y.), 2024-01, Vol.123, p.108523, Article 108523

2024

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Genotoxicity evaluation using primary hepatocytes isolated from rhesus macaque (Macaca mulatta)

Toxicology (Amsterdam), 2021-10, Vol.462 (C), p.152936-152936, Article 152936

2021

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HPLC-API/MS/MS: a powerful tool for integrating drug metabolism into the drug discovery process

Drug discovery today, 1997-12, Vol.2 (12), p.532-537

1997

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Effects of cellular differentiation in human primary bronchial epithelial cells: Metabolism of 4-(methylnitrosamine)-1-(3-pyridyl)-1-butanone

Toxicology in vitro, 2019-03, Vol.55, p.185-194

2019

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Use of a physiologically-based pharmacokinetic model to explore the potential disparity in nicotine disposition between adult and adolescent nonhuman primates

Toxicology and applied pharmacology, 2020-01, Vol.386, p.114826, Article 114826

2020

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NIEHS/FDA CLARITY-BPA research program update

Reproductive toxicology (Elmsford, N.Y.), 2015-12, Vol.58, p.33-44

2015

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Pharmacokinetic screening for the selection of new drug discovery candidates is greatly enhanced through the use of liquid chromatography–atmospheric pressure ionization tandem mass spectrometry

Journal of Chromatography A, 1997-08, Vol.777 (1), p.61-66

1997

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A sensitive and high-throughput LC―MS/MS method for the quantification of pegylated-interferon-α2a in human serum using monolithic C18 solid phase extraction for enrichment

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009-06, Vol.877 (18-19), p.1737-1742

2009

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Cytoto xicity of 34 FDA approved small - molecule kinase inhibitor s in primary rat and human hepatocytes

Toxicology letters, 2018-04

2018

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Discovery of nor-seco himbacine analogs as thrombin receptor antagonists

Bioorganic & medicinal chemistry letters, 2012-04, Vol.22 (7), p.2544-2549

2012

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A sensitive and high-throughput LC-MS/MS method for the quantification of pegylated-interferon-a sub(2a) in human serum using monolithic C sub(18) solid phase extraction for enrichment

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009-06, Vol.877 (18-19), p.1737-1742

2009

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A sensitive and high-throughput LC-MS/MS method for the quantification of pegylated-interferon-a@@d2a@ in human serum using monolithic C@@d18@ solid phase extraction for enrichment

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009-06, Vol.877 (18-19), p.1737-1742

2009

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The genotoxicity potential of luteolin is enhanced by CYP1A1 and CYP1A2 in human lymphoblastoid TK6 cells

The role of CYP 3A4 and 1A1 in amiodarone-induced hepatocellular toxicity

In vivo pharmacokinetic analyses of placental transfer of three drugs of different physicochemical properties in pregnant rats

Evaluation of pyrrolizidine alkaloid-induced genotoxicity using metabolically competent TK6 cell lines

90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats

Interstrain differences in the progression of nonalcoholic steatohepatitis to fibrosis in mice are associated with altered hepatic iron metabolism

Comparison of endpoints relevant to toxicity assessments in 3 generations of CD-1 mice fed irradiated natural and purified ingredient diets with varying soy protein and isoflavone contents

Model-based feedforward and cascade control of hydraulic McKibben muscles

Disease-related responses induced by cadmium in an in vitro human airway tissue model

In vitro dosimetry analyses for acrolein exposure in normal human lung epithelial cells and human lung cancer cells

Direct cocktail analysis of drug discovery compounds in pooled plasma samples using liquid chromatography–tandem mass spectrometry

Cytotoxicity of 34 FDA approved small-molecule kinase inhibitors in primary rat and human hepatocytes

Assessing the respiratory toxicity of dihydroxyacetone using an in vitro human airway epithelial tissue model

Evaluation of a microphysiological human placental barrier model for studying placental drug transfer

Genotoxicity evaluation using primary hepatocytes isolated from rhesus macaque (Macaca mulatta)

HPLC-API/MS/MS: a powerful tool for integrating drug metabolism into the drug discovery process

Effects of cellular differentiation in human primary bronchial epithelial cells: Metabolism of 4-(methylnitrosamine)-1-(3-pyridyl)-1-butanone

Use of a physiologically-based pharmacokinetic model to explore the potential disparity in nicotine disposition between adult and adolescent nonhuman primates

NIEHS/FDA CLARITY-BPA research program update

Pharmacokinetic screening for the selection of new drug discovery candidates is greatly enhanced through the use of liquid chromatography–atmospheric pressure ionization tandem mass spectrometry

A sensitive and high-throughput LC―MS/MS method for the quantification of pegylated-interferon-α2a in human serum using monolithic C18 solid phase extraction for enrichment

Cytoto xicity of 34 FDA approved small - molecule kinase inhibitor s in primary rat and human hepatocytes

Discovery of nor-seco himbacine analogs as thrombin receptor antagonists

A sensitive and high-throughput LC-MS/MS method for the quantification of pegylated-interferon-a sub(2a) in human serum using monolithic C sub(18) solid phase extraction for enrichment

A sensitive and high-throughput LC-MS/MS method for the quantification of pegylated-interferon-a@@d2a@ in human serum using monolithic C@@d18@ solid phase extraction for enrichment

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