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A Compendium of Mutational Signatures of Environmental Agents

Cell, 2019-05, Vol.177 (4), p.821-836.e16

2019

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Differential effects of nitro-PAHs and amino-PAHs on cytokine and chemokine responses in human bronchial epithelial BEAS-2B cells

Toxicology and applied pharmacology, 2010-02, Vol.242 (3), p.270-280

2010

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Polycyclic aromatic hydrocarbons as skin carcinogens: Comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse

Toxicology and applied pharmacology, 2012-11, Vol.264 (3), p.377-386

2012

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Metabolic activation of carcinogenic aristolochic acid, a risk factor for Balkan endemic nephropathy

Mutation research, 2008-01, Vol.658 (1-2), p.55-67

2008

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Congenital adrenal hyperplasia caused by mutant P450 oxidoreductase and human androgen synthesis: analytical study

The Lancet (British edition), 2004-06, Vol.363 (9427), p.2128-2135

2004

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P03-11 Assessing kinetic properties in food and feed: tebuconazole case study

Toxicology letters, 2024-09, Vol.399, p.S126-S126

2024

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Effects of nitrated-polycyclic aromatic hydrocarbons and diesel exhaust particle extracts on cell signalling related to apoptosis: Possible implications for their mutagenic and carcinogenic effects

Toxicology (Amsterdam), 2007-03, Vol.231 (2), p.159-174

2007

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Multi-steroid profiling by UHPLC-MS/MS with post-column infusion of ammonium fluoride

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2022-10, Vol.1209, p.123413-123413, Article 123413

2022

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The impact of chemotherapeutic drugs on the CYP1A1-catalysed metabolism of the environmental carcinogen benzo[a]pyrene: Effects in human colorectal HCT116 TP53(+/+), TP53(+/−) and TP53(−/−) cells

Toxicology (Amsterdam), 2018-04, Vol.398-399, p.1-12

2018

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Mutagenicity of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N–OH-PhIP) in human TP53 knock-in (Hupki) mouse embryo fibroblasts

Food and chemical toxicology, 2021-01, Vol.147, p.111855, Article 111855

2021

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Prostate cancer androgen biosynthesis relies solely on CYP17A1 downstream metabolites

The Journal of steroid biochemistry and molecular biology, 2024-02, Vol.236, p.106446-106446, Article 106446

2024

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Tu1375 A CASE-MATCHED STUDY ON EUS-GUIDED DRAINAGE OF WALLED-OFF NECROSIS USING 20MM VS 15MM LUMEN APPOSING METAL STENTS: IS BIGGER BETTER?

Gastrointestinal endoscopy, 2019-06, Vol.89 (6), p.AB597-AB598

2019

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TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblasts

DNA repair, 2016-03, Vol.39, p.21-33

2016

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Different mechanisms involved in apoptosis following exposure to benzo[ a]pyrene in F258 and Hepa1c1c7 cells

Chemico-biological interactions, 2007-04, Vol.167 (1), p.41-55

2007

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Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: Studies with the hepatic NADPH:Cytochrome P450 reductase null mouse

Toxicology and applied pharmacology, 2008-02, Vol.226 (3), p.318-327

2008

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The environmental pollutant and carcinogen 3-nitrobenzanthrone induces cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase in rat lung and kidney, thereby enhancing its own genotoxicity

Toxicology (Amsterdam), 2008-05, Vol.247 (1), p.11-22

2008

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The GSTM1null (deletion) and MGMT84 rs12917 (Phe/Phe) haplotype are associated with bulky DNA adduct levels in human leukocytes

Mutation research. Genetic toxicology and environmental mutagenesis, 2013-12, Vol.758 (1-2), p.62-68

2013

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Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts

Toxicology in vitro, 2015-02, Vol.29 (1), p.34-43

2015

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AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells

The Journal of steroid biochemistry and molecular biology, 2019-05, Vol.189, p.218-227

2019

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NADH:cytochrome b5 reductase and cytochrome b5 act as sole electron donors to human cytochrome P450 1A1-catalyzed oxidation and DNA adduct formation by benzo[a]pyrene

Toxicology letters, 2016-09, Vol.258, p.S96-S96

2016

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The genome as a record for environmental exposure to polycyclic aromatic hydrocarbons

Toxicology letters, 2017-10, Vol.280, p.S36-S36

2017

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NADPH- and NADH-dependent formation of DNA adducts by benzo[a]pyrene catalyzed with cytochrome P450 1A1

Toxicology letters, 2015-10, Vol.238 (2), p.S239-S239

2015

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Mycotoxin ochratoxin A decreases cytochrome P450-mediated detoxication of carcinogenic aristolochic acid thereby increases its genotoxic potential in rats in vivo

Toxicology letters, 2015-10, Vol.238 (2), p.S237-S237

2015

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Covalent binding of the anticancer drug ellipticine to DNA in V79 cells transfected with human cytochrome P450 enzymes

Biochemical pharmacology, 2002-07, Vol.64 (2), p.289-295

2002

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Environmental polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53 dependent mechanism

Toxicology letters, 2014-09, Vol.229, p.S156-S156

2014

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A Compendium of Mutational Signatures of Environmental Agents

Differential effects of nitro-PAHs and amino-PAHs on cytokine and chemokine responses in human bronchial epithelial BEAS-2B cells

Polycyclic aromatic hydrocarbons as skin carcinogens: Comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse

Metabolic activation of carcinogenic aristolochic acid, a risk factor for Balkan endemic nephropathy

Congenital adrenal hyperplasia caused by mutant P450 oxidoreductase and human androgen synthesis: analytical study

P03-11 Assessing kinetic properties in food and feed: tebuconazole case study

Effects of nitrated-polycyclic aromatic hydrocarbons and diesel exhaust particle extracts on cell signalling related to apoptosis: Possible implications for their mutagenic and carcinogenic effects

Multi-steroid profiling by UHPLC-MS/MS with post-column infusion of ammonium fluoride

The impact of chemotherapeutic drugs on the CYP1A1-catalysed metabolism of the environmental carcinogen benzo[a]pyrene: Effects in human colorectal HCT116 TP53(+/+), TP53(+/−) and TP53(−/−) cells

Mutagenicity of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N–OH-PhIP) in human TP53 knock-in (Hupki) mouse embryo fibroblasts

Prostate cancer androgen biosynthesis relies solely on CYP17A1 downstream metabolites

Tu1375 A CASE-MATCHED STUDY ON EUS-GUIDED DRAINAGE OF WALLED-OFF NECROSIS USING 20MM VS 15MM LUMEN APPOSING METAL STENTS: IS BIGGER BETTER?

TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblasts

Different mechanisms involved in apoptosis following exposure to benzo[ a]pyrene in F258 and Hepa1c1c7 cells

Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: Studies with the hepatic NADPH:Cytochrome P450 reductase null mouse

The environmental pollutant and carcinogen 3-nitrobenzanthrone induces cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase in rat lung and kidney, thereby enhancing its own genotoxicity

The GSTM1null (deletion) and MGMT84 rs12917 (Phe/Phe) haplotype are associated with bulky DNA adduct levels in human leukocytes

Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts

AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells

NADH:cytochrome b5 reductase and cytochrome b5 act as sole electron donors to human cytochrome P450 1A1-catalyzed oxidation and DNA adduct formation by benzo[a]pyrene

The genome as a record for environmental exposure to polycyclic aromatic hydrocarbons

NADPH- and NADH-dependent formation of DNA adducts by benzo[a]pyrene catalyzed with cytochrome P450 1A1

Mycotoxin ochratoxin A decreases cytochrome P450-mediated detoxication of carcinogenic aristolochic acid thereby increases its genotoxic potential in rats in vivo

Covalent binding of the anticancer drug ellipticine to DNA in V79 cells transfected with human cytochrome P450 enzymes

Environmental polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53 dependent mechanism

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