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Ligand-dependent transcriptional induction of lethal autophagy: A new perspective for cancer treatment
Autophagy, 2018-03, Vol.14 (3), p.555-557
2018
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Dendrogenin A drives LXR to trigger lethal autophagy in cancers
Nature communications, 2017-12, Vol.8 (1), p.1903-17, Article 1903
2017
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Identification and pharmacological characterization of cholesterol-5,6-epoxide hydrolase as a target for tamoxifen and AEBS ligands
Proceedings of the National Academy of Sciences - PNAS, 2010-07, Vol.107 (30), p.13520-13525
2010
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Tamoxifen and AEBS ligands induced apoptosis and autophagy in breast cancer cells through the stimulation of sterol accumulation
Autophagy, 2009-10, Vol.5 (7), p.1066-1067
2009
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Surprising unreactivity of cholesterol-5,6-epoxides towards nucleophiles
Journal of lipid research, 2012-04, Vol.53 (4), p.718-725
2012
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Signaling through cholesterol esterification: a new pathway for the cholecystokinin 2 receptor involved in cell growth and invasion
Journal of lipid research, 2009-11, Vol.50 (11), p.2203-2211
2009
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Auraptene is an inhibitor of cholesterol esterification and a modulator of estrogen receptors
Molecular pharmacology, 2010-11, Vol.78 (5), p.827-836
2010
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Bryonolic Acid Blocks Cancer Cell Clonogenicity and Invasiveness through the Inhibition of Fatty Acid: Cholesteryl Ester Formation
Biomedicines, 2018-02, Vol.6 (1), p.21
2018
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Microsomal antiestrogen-binding site ligands induce growth control and differentiation of human breast cancer cells through the modulation of cholesterol metabolism
Molecular cancer therapeutics, 2008-12, Vol.7 (12), p.3707-3718
2008
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Molecular Characterization of the Microsomal Tamoxifen Binding Site
The Journal of biological chemistry, 2004-08, Vol.279 (32), p.34048-34061
2004
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Tamoxifen is a potent inhibitor of cholesterol esterification and prevents the formation of foam cells
The Journal of pharmacology and experimental therapeutics, 2004-03, Vol.308 (3), p.1165
2004
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High tumorigenic potential of a constitutively active mutant of the cholecystokinin 2 receptor
Oncogene, 2003-09, Vol.22 (38), p.6081-6089
2003
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Ligands of the antiestrogen-binding site induce active cell death and autophagy in human breast cancer cells through the modulation of cholesterol metabolism
Cell death and differentiation, 2009-10, Vol.16 (10), p.1372-1384
2009
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Insights into the Cholecystokinin 2 Receptor Binding Site and Processes of Activation
Molecular pharmacology, 2006-12, Vol.70 (6), p.1935-1945
2006
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Identification of Tyrosine 189 and Asparagine 358 of the Cholecystokinin 2 Receptor in Direct Interaction with the Crucial C-Terminal Amide of Cholecystokinin by Molecular Modeling, Site-Directed Mutagenesis, and Structure/Affinity Studies
Molecular pharmacology, 2003-05, Vol.63 (5), p.973-982
2003
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Cancer. Cholesterol and cancer, in the balance
Science (American Association for the Advancement of Science), 2014-03, Vol.343 (6178), p.1445-1446
2014
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Dendrogenin A arises from cholesterol and histamine metabolism and shows cell differentiation and anti-tumour properties
Nature communications, 2013, Vol.4 (1), p.1840, Article 1840
2013
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Antiestrogen-binding site ligands induce autophagy in myeloma cells that proceeds through alteration of cholesterol metabolism
Oncotarget, 2013-06, Vol.4 (6), p.911-922
2013
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