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Pteridine biosynthesis in human endothelial cells. Impact on nitric oxide-mediated formation of cyclic GMP

The Journal of biological chemistry, 1993-01, Vol.268 (3), p.1842-1846

1993

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Brain nitric oxide synthase is a biopterin- and flavin-containing multi-functional oxido-reductase

FEBS letters, 1991-08, Vol.288 (1-2), p.187-191

1991

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Tetrahydrobiopterin-dependent formation of nitrite and nitrate in murine fibroblasts

The Journal of experimental medicine, 1990-12, Vol.172 (6), p.1599-1607

1990

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Neopterin modulates toxicity mediated by reactive oxygen and chloride species

FEBS letters, 1993-04, Vol.321 (1), p.89-92

1993

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Tetrahydrobiopterin-dependent formation of endothelium-derived relaxing factor (nitric oxide) in aortic endothelial cells

Biochemical journal, 1992-01, Vol.281 (2), p.297-300

1992

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Importance of vpr for infection of rhesus monkeys with simian immunodeficiency virus

Journal of Virology, 1993-02, Vol.67 (2), p.902-912

1993

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Tetrahydrobiopterin biosynthetic activities in human macrophages, fibroblasts, THP-1, and T 24 cells. GTP-cyclohydrolase I is stimulated by interferon-gamma, and 6-pyruvoyl tetrahydropterin synthase and sepiapterin reductase are constitutively present

The Journal of biological chemistry, 1990-02, Vol.265 (6), p.3189-3192

1990

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Identification of the 4-amino analogue of tetrahydrobiopterin as a dihydropteridine reductase inhibitor and a potent pteridine antagonist of rat neuronal nitric oxide synthase

Biochemical journal, 1996-11, Vol.320 ( Pt 1) (1), p.193-196

1996

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Tetrahydrobiopterin and Cytokines

Proceedings of the Society for Experimental Biology and Medicine, 1993-05, Vol.203 (1), p.1-12

1993

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Immune response-associated production of neopterin. Release from macrophages primarily under control of interferon-gamma

The Journal of experimental medicine, 1984-07, Vol.160 (1), p.310-316

1984

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Enhancement of hydrogen peroxide-induced luminol-dependent chemiluminescence by neopterin depends on the presence of iron chelator complexes

FEBS letters, 1994-01, Vol.338 (2), p.223-226

1994

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Differential patterns of serum biomarkers of immune activation in human T-cell lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis, and adult T-cell leukemia/lymphoma

Cancer epidemiology, biomarkers & prevention, 1996-09, Vol.5 (9), p.699-704

1996

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Parallel induction of tetrahydrobiopterin biosynthesis and indoleamine 2,3-dioxygenase activity in human cells and cell lines by interferon-gamma

Biochemical journal, 1989-09, Vol.262 (3), p.861-866

1989

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Decreased plasma concentrations of HDL cholesterol in HIV-infected individuals are associated with immune activation

Journal of acquired immune deficiency syndromes (1988), 1994-11, Vol.7 (11), p.1149-1156

1994

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Effect of neopterin and 7,8-dihydroneopterin on tumor necrosis factor-α induced programmed cell death

FEBS letters, 1995-05, Vol.364 (2), p.234-238

1995

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Weight loss in HIV-1 infection is associated with immune activation

AIDS (London), 1993-02, Vol.7 (2), p.175-181

1993

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Increased serum concentrations of soluble tumor necrosis factor receptors in HIV-infected individuals are associated with immune activation

Journal of acquired immune deficiency syndromes (1988), 1994, Vol.7 (1), p.79-85

1994

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Neopterin formation and tryptophan degradation by a human myelomonocytic cell line (THP-1) upon cytokine treatment

Cancer research (Chicago, Ill.), 1990-05, Vol.50 (10), p.2863-2867

1990

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Determination of neopterin in serum and urine

Clinical chemistry (Baltimore, Md.), 1987-01, Vol.33 (1), p.62

1987

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Decreased serum tryptophan in patients with HIV-1 infection correlates with increased serum neopterin and with neurologic/psychiatric symptoms

Journal of acquired immune deficiency syndromes (1988), 1990, Vol.3 (9), p.873-876

1990

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Induction of GTP cyclohydrolase I by bacterial lipopolysaccharide in the rat

FEBS letters, 1993-05, Vol.322 (3), p.223-226

1993

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Markers for disease progression in intravenous drug users infected with HIV-1

AIDS (London), 1991-08, Vol.5 (8), p.985-991

1991

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Immunologic Markers of Progression to Acquired Immunodeficiency Syndrome are Time-Dependent and Illness-Specific

American journal of epidemiology, 1992-07, Vol.136 (1), p.71-80

1992

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Neopterin as a predictive marker for disease progression in human immunodeficiency virus type 1 infection

Clinical chemistry (Baltimore, Md.), 1989-08, Vol.35 (8), p.1746

1989

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Impact of tumour necrosis factor-α and interferon-γ on tetrahydrobiopterin synthesis in murine fibroblasts and macrophages

Biochemical journal, 1991-12, Vol.280 (3), p.709-714

1991

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Pteridine biosynthesis in human endothelial cells. Impact on nitric oxide-mediated formation of cyclic GMP

Brain nitric oxide synthase is a biopterin- and flavin-containing multi-functional oxido-reductase

Tetrahydrobiopterin-dependent formation of nitrite and nitrate in murine fibroblasts

Neopterin modulates toxicity mediated by reactive oxygen and chloride species

Tetrahydrobiopterin-dependent formation of endothelium-derived relaxing factor (nitric oxide) in aortic endothelial cells

Importance of vpr for infection of rhesus monkeys with simian immunodeficiency virus

Tetrahydrobiopterin biosynthetic activities in human macrophages, fibroblasts, THP-1, and T 24 cells. GTP-cyclohydrolase I is stimulated by interferon-gamma, and 6-pyruvoyl tetrahydropterin synthase and sepiapterin reductase are constitutively present

Identification of the 4-amino analogue of tetrahydrobiopterin as a dihydropteridine reductase inhibitor and a potent pteridine antagonist of rat neuronal nitric oxide synthase

Tetrahydrobiopterin and Cytokines

Immune response-associated production of neopterin. Release from macrophages primarily under control of interferon-gamma

Enhancement of hydrogen peroxide-induced luminol-dependent chemiluminescence by neopterin depends on the presence of iron chelator complexes

Differential patterns of serum biomarkers of immune activation in human T-cell lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis, and adult T-cell leukemia/lymphoma

Parallel induction of tetrahydrobiopterin biosynthesis and indoleamine 2,3-dioxygenase activity in human cells and cell lines by interferon-gamma

Decreased plasma concentrations of HDL cholesterol in HIV-infected individuals are associated with immune activation

Effect of neopterin and 7,8-dihydroneopterin on tumor necrosis factor-α induced programmed cell death

Weight loss in HIV-1 infection is associated with immune activation

Increased serum concentrations of soluble tumor necrosis factor receptors in HIV-infected individuals are associated with immune activation

Neopterin formation and tryptophan degradation by a human myelomonocytic cell line (THP-1) upon cytokine treatment

Determination of neopterin in serum and urine

Decreased serum tryptophan in patients with HIV-1 infection correlates with increased serum neopterin and with neurologic/psychiatric symptoms

Induction of GTP cyclohydrolase I by bacterial lipopolysaccharide in the rat

Markers for disease progression in intravenous drug users infected with HIV-1

Immunologic Markers of Progression to Acquired Immunodeficiency Syndrome are Time-Dependent and Illness-Specific

Neopterin as a predictive marker for disease progression in human immunodeficiency virus type 1 infection

Impact of tumour necrosis factor-α and interferon-γ on tetrahydrobiopterin synthesis in murine fibroblasts and macrophages

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