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Increased membrane cholesterol in lymphocytes diverts T-cells toward an inflammatory response

PloS one, 2012-06, Vol.7 (6), p.e38733

2012

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Reconstitution of human microglia and resident T cells in the brain of humanized DRAGA mice

Frontiers in cellular and infection microbiology, 2024-06, Vol.14, p.1367566

2024

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The humanized DRAGA mouse (HLA-A2. HLA-DR4. RAG1 KO. IL-2R g c KO. NOD) establishes inducible and transmissible models for influenza type A infections

Human vaccines & immunotherapeutics, 2020-09, Vol.16 (9), p.2222-2237

2020

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Human-Immune-System (HIS) humanized mouse model (DRAGA: HLA-A2.HLA-DR4.Rag1KO.IL-2RγcKO.NOD) for COVID-19

Human vaccines & immunotherapeutics, 2022-11, Vol.18 (5), p.2048622-2048622

2022

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Generation and testing anti-influenza human monoclonal antibodies in a new humanized mouse model (DRAGA: HLA-A2. HLA-DR4. Rag1 KO. IL-2Rγc KO. NOD)

Human vaccines & immunotherapeutics, 2018-02, Vol.14 (2), p.345-360

2018

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Humanized DRAGA mice immunized with Plasmodium falciparum sporozoites and chloroquine elicit protective pre-erythrocytic immunity

Malaria journal, 2018-03, Vol.17 (1), p.114-114, Article 114

2018

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Double Negative (CD3+4−8−) TCRαβ Splenic Cells from Young NOD Mice Provide Long-Lasting Protection against Type 1 Diabetes

PloS one, 2010-07, Vol.5 (7), p.e11427

2010

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Humanized HLA-DR4 mice fed with the protozoan pathogen of oysters Perkinsus marinus (Dermo) do not develop noticeable pathology but elicit systemic immunity

PloS one, 2014-01, Vol.9 (1), p.e87435-e87435

2014

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Differential effect of HLA class-I versus class-II transgenes on human T and B cell reconstitution and function in NRG mice

Scientific reports, 2016-06, Vol.6 (1), p.28093-28093, Article 28093

2016

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Nonobese Diabetic (NOD) Mice Lack a Protective B-Cell Response against the “Nonlethal” Plasmodium yoelii 17XNL Malaria Protozoan

Malaria research and treatment, 2016, Vol.2016, p.6132734-9

2016

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Long-term silencing of autoimmune diabetes and improved life expectancy by a soluble pHLA-DR4 chimera in a newly-humanized NOD/DR4/B7 mouse

Human vaccines & immunotherapeutics, 2014-03, Vol.10 (3), p.693-699

2014

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Humanized HLA-DR4.RagKO.IL2RγcKO.NOD (DRAG) mice sustain the complex vertebrate life cycle of Plasmodium falciparum malaria

Malaria journal, 2014-09, Vol.13 (1), p.386-386, Article 386

2014

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Down-regulation of autoreactive T-cells by HMG CoA reductase inhibitors

Clinical Immunology, 2006-04, Vol.119 (1), p.1-12

2006

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Differential partitioning and trafficking of GM gangliosides and cholesterol-rich lipid rafts in thymic and splenic CD4 T cells

Molecular Immunology, 2007, Vol.44 (4), p.530-540

2007

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Double Negative (CD3+4−8−) TCRαβ Splenic Cells from Young NOD Mice Provide Long-Lasting Protection against Type 1 Diabetes

PloS one, 2010-07, Vol.5 (7), p.e11427

2010

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Soluble, dimeric HLA DR4‐peptide chimeras: An approach for detection and immunoregulation of human type‐1 diabetes

European Journal of Immunology, 2005-09, Vol.35 (9), p.2762-2775

2005

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Reversal of type 1 diabetes by a new MHC II‐peptide chimera: “Single‐epitope‐mediated suppression” to stabilize a polyclonal autoimmune T‐cell process

European journal of immunology, 2010-08, Vol.40 (8), p.2277-2288

2010

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Enzymatically mediated engineering of multivalent MHC class II–peptide chimeras

Protein engineering, 2001-03, Vol.14 (3), p.195-200

2001

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CD28 Signaling in T Regulatory Precursors Requires p56lck and Rafts Integrity to Stabilize the Foxp3 Message

The Journal of immunology (1950), 2009-01, Vol.182 (1), p.102-110

2009

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Antineoplastic efficacy of doxorubicin enzymatically assembled on galactose residues of a monoclonal antibody specific for the carcinoembryonic antigen

Cancer research (Chicago, Ill.), 1999, Vol.59 (1), p.115-121

1999

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Thymic Development of CD4+25hi Foxp3+ T-Regulatory Cells Echoes their Suppressogenic Capacity in Periphery

The Open autoimmunity journal, 2009-07, Vol.1 (1), p.64-78

2009

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Double negative (CD3+ 4- 8-) TCR alphabeta splenic cells from young NOD mice provide long-lasting protection against type 1 diabetes

PloS one, 2010-07, Vol.5 (7), p.e11427-e11427

2010

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Humanized HLA-DR4.RagKO.IL2R[gamma]cKO.NOD mice sustain the complex vertebrate life cycle of Plasmodium falciparum malaria

Malaria journal, 2014-09, Vol.13 (1), p.386-386

2014

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Humanized HLA-DR4 Mice Fed with the Protozoan Pathogen of Oysters Perkinsus Marinus

PloS one, 2014-01, Vol.9 (1), p.e87435

2014

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Double Negative

PloS one, 2010-07, Vol.5 (7), p.e11427

2010

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Increased membrane cholesterol in lymphocytes diverts T-cells toward an inflammatory response

Reconstitution of human microglia and resident T cells in the brain of humanized DRAGA mice

The humanized DRAGA mouse (HLA-A2. HLA-DR4. RAG1 KO. IL-2R g c KO. NOD) establishes inducible and transmissible models for influenza type A infections

Human-Immune-System (HIS) humanized mouse model (DRAGA: HLA-A2.HLA-DR4.Rag1KO.IL-2RγcKO.NOD) for COVID-19

Generation and testing anti-influenza human monoclonal antibodies in a new humanized mouse model (DRAGA: HLA-A2. HLA-DR4. Rag1 KO. IL-2Rγc KO. NOD)

Humanized DRAGA mice immunized with Plasmodium falciparum sporozoites and chloroquine elicit protective pre-erythrocytic immunity

Double Negative (CD3+4−8−) TCRαβ Splenic Cells from Young NOD Mice Provide Long-Lasting Protection against Type 1 Diabetes

Humanized HLA-DR4 mice fed with the protozoan pathogen of oysters Perkinsus marinus (Dermo) do not develop noticeable pathology but elicit systemic immunity

Differential effect of HLA class-I versus class-II transgenes on human T and B cell reconstitution and function in NRG mice

Nonobese Diabetic (NOD) Mice Lack a Protective B-Cell Response against the “Nonlethal” Plasmodium yoelii 17XNL Malaria Protozoan

Long-term silencing of autoimmune diabetes and improved life expectancy by a soluble pHLA-DR4 chimera in a newly-humanized NOD/DR4/B7 mouse

Humanized HLA-DR4.RagKO.IL2RγcKO.NOD (DRAG) mice sustain the complex vertebrate life cycle of Plasmodium falciparum malaria

Down-regulation of autoreactive T-cells by HMG CoA reductase inhibitors

Differential partitioning and trafficking of GM gangliosides and cholesterol-rich lipid rafts in thymic and splenic CD4 T cells

Double Negative (CD3+4−8−) TCRαβ Splenic Cells from Young NOD Mice Provide Long-Lasting Protection against Type 1 Diabetes

Soluble, dimeric HLA DR4‐peptide chimeras: An approach for detection and immunoregulation of human type‐1 diabetes

Reversal of type 1 diabetes by a new MHC II‐peptide chimera: “Single‐epitope‐mediated suppression” to stabilize a polyclonal autoimmune T‐cell process

Enzymatically mediated engineering of multivalent MHC class II–peptide chimeras

CD28 Signaling in T Regulatory Precursors Requires p56lck and Rafts Integrity to Stabilize the Foxp3 Message

Antineoplastic efficacy of doxorubicin enzymatically assembled on galactose residues of a monoclonal antibody specific for the carcinoembryonic antigen

Thymic Development of CD4+25hi Foxp3+ T-Regulatory Cells Echoes their Suppressogenic Capacity in Periphery

Double negative (CD3+ 4- 8-) TCR alphabeta splenic cells from young NOD mice provide long-lasting protection against type 1 diabetes

Humanized HLA-DR4.RagKO.IL2R[gamma]cKO.NOD mice sustain the complex vertebrate life cycle of Plasmodium falciparum malaria

Humanized HLA-DR4 Mice Fed with the Protozoan Pathogen of Oysters Perkinsus Marinus

Double Negative

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