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Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells

Nature communications, 2017-11, Vol.8 (1), p.1576-13, Article 1576

2017

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CCL20 neutralization by a monoclonal antibody in healthy subjects selectively inhibits recruitment of CCR6+ cells in an experimental suction blister

British journal of clinical pharmacology, 2017-09, Vol.83 (9), p.1976-1990

2017

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Follicular Dendritic Cells Modulate Germinal Center B Cell Diversity through FcγRIIB

Cell reports (Cambridge), 2019-11, Vol.29 (9), p.2745-2755.e4

2019

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Immune complex disease in a chronic monkey study with a humanised, therapeutic antibody against CCL20 is associated with complement-containing drug aggregates

PloS one, 2020-04, Vol.15 (4), p.e0231655

2020

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Exacerbated experimental arthritis in Wiskott–Aldrich syndrome protein deficiency: Modulatory role of regulatory B cells

European journal of immunology, 2014-09, Vol.44 (9), p.2692-2702

2014

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Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis

Blood, 2008-11, Vol.112 (10), p.4158-4169

2008

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Nonintegrating Lentivector Vaccines Stimulate Prolonged T-Cell and Antibody Responses and Are Effective in Tumor Therapy

Journal of Virology, 2009-04, Vol.83 (7), p.3094-3103

2009

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The Wiskott-Aldrich syndrome: The actin cytoskeleton and immune cell function

Disease markers, 2010, Vol.29 (3-4), p.157-175

2010

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Increased Serum Levels of MRP-8/14 in Type 1 Diabetes Induce an Increased Expression of CD11b and an Enhanced Adhesion of Circulating Monocytes to Fibronectin

Diabetes (New York, N.Y.), 2004-08, Vol.53 (8), p.1979-1986

2004

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Phosphorylation of WASp is a key regulator of activity and stability in vivo

Proceedings of the National Academy of Sciences - PNAS, 2009-09, Vol.106 (37), p.15738-15743

2009

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Improvement of Migratory Defects in a Murine Model of Wiskott–Aldrich Syndrome Gene Therapy

Molecular therapy, 2008-05, Vol.16 (5), p.836-844

2008

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Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse

Wellcome open research, 2018, Vol.3, p.84-84

2018

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Impaired neutrophil migration and phagocytosis in IRAK‐4 deficiency

British journal of haematology, 2009-10, Vol.147 (1), p.153-156

2009

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Diabetes-prone NOD mice show an expanded subpopulation of mature circulating monocytes, which preferentially develop into macrophage-like cells in vitro

Journal of leukocyte biology, 2005-07, Vol.78 (1), p.70-79

2005

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The Phase 3 Natron Study Evaluating Benralizumab in Patients with Hypereosinophilic Syndrome: Study Design and Patient Characteristics

Blood, 2023-11, Vol.142 (Supplement 1), p.1172-1172

2023

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Su1794 TOLERABILITY, SAFETY, AND CLINICAL PHARMACOLOGY OF AZD7798, A DEPLETING ANTIBODY TARGETING CCR9

Gastroenterology (New York, N.Y. 1943), 2024-05, Vol.166 (5), p.S-816-S-817

2024

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Sa2018 FIRST-TIME-IN-HUMAN VISUALISATION OF CCR9 EXPRESSION IN THE GUT BY POSITRON EMISSION TOMOGRAPHY

Gastroenterology (New York, N.Y. 1943), 2024-05, Vol.166 (5), p.S-605-S-605

2024

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WASp‐dependent actin cytoskeleton stability at the dendritic cell immunological synapse is required for extensive, functional T cell contacts

Journal of leukocyte biology, 2016-05, Vol.99 (5), p.699-710

2016

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A randomised, double‐blind, placebo‐controlled study of the LAG‐3‐depleting monoclonal antibody GSK2831781 in patients with active ulcerative colitis

Alimentary pharmacology & therapeutics, 2023-08, Vol.58 (3), p.283-296

2023

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Immunodeficiency and severe susceptibility to bacterial infection associated with a loss-of-function homozygous mutation of MKL1

Blood, 2015-09, Vol.126 (13), p.1527-1535

2015

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Epigenetically quantified immune cells in salivary glands of Sjögren’s syndrome patients: a novel tool that detects robust correlations of T follicular helper cells with immunopathology

Rheumatology (Oxford, England), 2020-02, Vol.59 (2), p.335-343

2020

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Structure and Functional Characterization of a Humanized Anti-CCL20 Antibody following Exposure to Serum Reveals the Formation of Immune Complex That Leads to Toxicity

The Journal of immunology (1950), 2021-03, Vol.206 (5), p.1067-1076

2021

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Recent advances in the understanding of genetic defects of neutrophil number and function

British journal of haematology, 2010-11, Vol.151 (4), p.312-326

2010

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The Wiskott-Aldrich syndrome: The actin cytoskeleton and immune cell function

Disease markers, 2010-01, Vol.29 (3-4), p.157-175

2010

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Functional gap junctions accumulate at the immunological synapse and contribute to T cell activation

The Journal of immunology (1950), 2011-09, Vol.187 (6), p.3121-3132

2011

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Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells

CCL20 neutralization by a monoclonal antibody in healthy subjects selectively inhibits recruitment of CCR6+ cells in an experimental suction blister

Follicular Dendritic Cells Modulate Germinal Center B Cell Diversity through FcγRIIB

Immune complex disease in a chronic monkey study with a humanised, therapeutic antibody against CCL20 is associated with complement-containing drug aggregates

Exacerbated experimental arthritis in Wiskott–Aldrich syndrome protein deficiency: Modulatory role of regulatory B cells

Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis

Nonintegrating Lentivector Vaccines Stimulate Prolonged T-Cell and Antibody Responses and Are Effective in Tumor Therapy

The Wiskott-Aldrich syndrome: The actin cytoskeleton and immune cell function

Increased Serum Levels of MRP-8/14 in Type 1 Diabetes Induce an Increased Expression of CD11b and an Enhanced Adhesion of Circulating Monocytes to Fibronectin

Phosphorylation of WASp is a key regulator of activity and stability in vivo

Improvement of Migratory Defects in a Murine Model of Wiskott–Aldrich Syndrome Gene Therapy

Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse

Impaired neutrophil migration and phagocytosis in IRAK‐4 deficiency

Diabetes-prone NOD mice show an expanded subpopulation of mature circulating monocytes, which preferentially develop into macrophage-like cells in vitro

The Phase 3 Natron Study Evaluating Benralizumab in Patients with Hypereosinophilic Syndrome: Study Design and Patient Characteristics

Su1794 TOLERABILITY, SAFETY, AND CLINICAL PHARMACOLOGY OF AZD7798, A DEPLETING ANTIBODY TARGETING CCR9

Sa2018 FIRST-TIME-IN-HUMAN VISUALISATION OF CCR9 EXPRESSION IN THE GUT BY POSITRON EMISSION TOMOGRAPHY

WASp‐dependent actin cytoskeleton stability at the dendritic cell immunological synapse is required for extensive, functional T cell contacts

A randomised, double‐blind, placebo‐controlled study of the LAG‐3‐depleting monoclonal antibody GSK2831781 in patients with active ulcerative colitis

Immunodeficiency and severe susceptibility to bacterial infection associated with a loss-of-function homozygous mutation of MKL1

Epigenetically quantified immune cells in salivary glands of Sjögren’s syndrome patients: a novel tool that detects robust correlations of T follicular helper cells with immunopathology

Structure and Functional Characterization of a Humanized Anti-CCL20 Antibody following Exposure to Serum Reveals the Formation of Immune Complex That Leads to Toxicity

Recent advances in the understanding of genetic defects of neutrophil number and function

The Wiskott-Aldrich syndrome: The actin cytoskeleton and immune cell function

Functional gap junctions accumulate at the immunological synapse and contribute to T cell activation

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