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Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice

Cell host & microbe, 2016-02, Vol.19 (2), p.181-193

2016

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Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity

The Journal of biological chemistry, 2020-12, Vol.295 (52), p.17986-17996

2020

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The coronavirus macrodomain is required to prevent PARP-mediated inhibition of virus replication and enhancement of IFN expression

PLoS pathogens, 2019-05, Vol.15 (5), p.e1007756-e1007756

2019

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The Viral Macrodomain Counters Host Antiviral ADP-Ribosylation

Viruses, 2020-03, Vol.12 (4), p.384

2020

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The coronavirus nucleocapsid protein is ADP-ribosylated

Virology (New York, N.Y.), 2018-04, Vol.517, p.62-68

2018

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MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection

PLoS pathogens, 2018-01, Vol.14 (1), p.e1006838-e1006838

2018

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The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection

mBio, 2016-12, Vol.7 (6)

2016

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Control the Host Cell Cycle: Viral Regulation of the Anaphase-Promoting Complex

Journal of Virology, 2013-08, Vol.87 (16), p.8818-8825

2013

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Coronaviruses: an overview of their replication and pathogenesis

Methods in molecular biology (Clifton, N.J.), 2015, Vol.1282, p.1

2015

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Cyclin A degradation by primate cytomegalovirus protein pUL21a counters its innate restriction of virus replication

PLoS pathogens, 2013-12, Vol.9 (12), p.e1003825-e1003825

2013

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Virus-induced inflammasome activation is suppressed by prostaglandin D₂/DP1 signaling

Proceedings of the National Academy of Sciences - PNAS, 2017-07, Vol.114 (27), p.E5444-E5453

2017

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The impact of PARPs and ADP-ribosylation on inflammation and host-pathogen interactions

Genes & development, 2020-03, Vol.34 (5-6), p.341-359

2020

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An Update on the Current State of SARS-CoV-2 Mac1 Inhibitors

Pathogens (Basel), 2023-10, Vol.12 (10), p.1221

2023

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The Human Cytomegalovirus Gene UL79 Is Required for the Accumulation of Late Viral Transcripts

Journal of Virology, 2011-05, Vol.85 (10), p.4841-4852

2011

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Human Cytomegalovirus Early Protein pUL21a Promotes Efficient Viral DNA Synthesis and the Late Accumulation of Immediate-Early Transcripts

Journal of Virology, 2011-01, Vol.85 (2), p.663-674

2011

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Human Cytomegalovirus Infection of Langerhans-Type Dendritic Cells Does Not Require the Presence of the gH/gL/UL128-131A Complex and Is Blocked after Nuclear Deposition of Viral Genomes in Immature Cells

Journal of Virology, 2014-01, Vol.88 (1), p.403-416

2014

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Human Cytomegalovirus Gene UL21a Encodes a Short-Lived Cytoplasmic Protein and Facilitates Virus Replication in Fibroblasts

Journal of Virology, 2010-01, Vol.84 (1), p.291-302

2010

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β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway

Cell, 2020-12, Vol.183 (6), p.1520-1535.e14

2020

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ADP‐ribosyltransferases, an update on function and nomenclature

The FEBS journal, 2022-12, Vol.289 (23), p.7399-7410

2022

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In Vitro and In Vivo Characterization of the Pseudomonas aeruginosa Cyclic AMP (cAMP) Phosphodiesterase CpdA, Required for cAMP Homeostasis and Virulence Factor Regulation

Journal of Bacteriology, 2010-06, Vol.192 (11), p.2779-2790

2010

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Inhibitors of One or More Cellular Aurora Kinases Impair the Replication of Herpes Simplex Virus 1 and Other DNA and RNA Viruses with Diverse Genomes and Life Cycles

Microbiology spectrum, 2023-02, Vol.11 (1), p.e0194322

2023

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Selective Packaging in Murine Coronavirus Promotes Virulence by Limiting Type I Interferon Responses

mBio, 2018-05, Vol.9 (3)

2018

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Murine Coronavirus Infection Activates the Aryl Hydrocarbon Receptor in an Indoleamine 2,3-Dioxygenase-Independent Manner, Contributing to Cytokine Modulation and Proviral TCDD-Inducible-PARP Expression

Journal of virology, 2020-01, Vol.94 (3)

2020

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Proteasome-dependent disruption of the E3 ubiquitin ligase anaphase-promoting complex by HCMV protein pUL21a

PLoS pathogens, 2012-07, Vol.8 (7), p.e1002789

2012

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Murine Cytomegalovirus Protein pM79 Is a Key Regulator for Viral Late Transcription

Journal of Virology, 2013-08, Vol.87 (16), p.9135-9147

2013

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Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice

Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity

The coronavirus macrodomain is required to prevent PARP-mediated inhibition of virus replication and enhancement of IFN expression

The Viral Macrodomain Counters Host Antiviral ADP-Ribosylation

The coronavirus nucleocapsid protein is ADP-ribosylated

MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection

The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection

Control the Host Cell Cycle: Viral Regulation of the Anaphase-Promoting Complex

Coronaviruses: an overview of their replication and pathogenesis

Cyclin A degradation by primate cytomegalovirus protein pUL21a counters its innate restriction of virus replication

Virus-induced inflammasome activation is suppressed by prostaglandin D₂/DP1 signaling

The impact of PARPs and ADP-ribosylation on inflammation and host-pathogen interactions

An Update on the Current State of SARS-CoV-2 Mac1 Inhibitors

The Human Cytomegalovirus Gene UL79 Is Required for the Accumulation of Late Viral Transcripts

Human Cytomegalovirus Early Protein pUL21a Promotes Efficient Viral DNA Synthesis and the Late Accumulation of Immediate-Early Transcripts

Human Cytomegalovirus Infection of Langerhans-Type Dendritic Cells Does Not Require the Presence of the gH/gL/UL128-131A Complex and Is Blocked after Nuclear Deposition of Viral Genomes in Immature Cells

Human Cytomegalovirus Gene UL21a Encodes a Short-Lived Cytoplasmic Protein and Facilitates Virus Replication in Fibroblasts

β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway

ADP‐ribosyltransferases, an update on function and nomenclature

In Vitro and In Vivo Characterization of the Pseudomonas aeruginosa Cyclic AMP (cAMP) Phosphodiesterase CpdA, Required for cAMP Homeostasis and Virulence Factor Regulation

Inhibitors of One or More Cellular Aurora Kinases Impair the Replication of Herpes Simplex Virus 1 and Other DNA and RNA Viruses with Diverse Genomes and Life Cycles

Selective Packaging in Murine Coronavirus Promotes Virulence by Limiting Type I Interferon Responses

Murine Coronavirus Infection Activates the Aryl Hydrocarbon Receptor in an Indoleamine 2,3-Dioxygenase-Independent Manner, Contributing to Cytokine Modulation and Proviral TCDD-Inducible-PARP Expression

Proteasome-dependent disruption of the E3 ubiquitin ligase anaphase-promoting complex by HCMV protein pUL21a

Murine Cytomegalovirus Protein pM79 Is a Key Regulator for Viral Late Transcription

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