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Clinical implications of trials investigating drug‐drug interactions between cannabidiol and enzyme inducers or inhibitors or common antiseizure drugs

Epilepsia (Copenhagen), 2020-09, Vol.61 (9), p.1854-1868

2020

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Associations of CYP2C9 and CYP2A6 Polymorphisms with the Concentrations of Valproate and its Hepatotoxin Metabolites and Valproate‐Induced Hepatotoxicity

Basic & clinical pharmacology & toxicology, 2017-08, Vol.121 (2), p.138-143

2017

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Effect of Age, Comedications, and CYP3A4/5 Polymorphisms on Perampanel Exposure in Chinese Pediatric Patients With Epilepsy

Journal of clinical pharmacology, 2024-06, Vol.64 (6), p.737-743

2024

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Effects of long-term antiepileptic drug monotherapy on vascular risk factors and atherosclerosis

Epilepsia (Copenhagen), 2012-01, Vol.53 (1), p.120-128

2012

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Intentional use of carbapenem antibiotics for valproic acid toxicity: A case report

Journal of clinical pharmacy and therapeutics, 2018-10, Vol.43 (5), p.723-725

2018

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Interactions between cannabidiol and commonly used antiepileptic drugs

Epilepsia (Copenhagen), 2017-09, Vol.58 (9), p.1586-1592

2017

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Dravet syndrome: Treatment options and management of prolonged seizures

Epilepsia (Copenhagen), 2019-12, Vol.60 (S3), p.S39-S48

2019

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Flucloxacillin instantly decreases serum levels of valproic acid: A case report

British journal of clinical pharmacology, 2024-11, Vol.90 (11), p.2931-2934

2024

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The Teratogenic Potencies of Valproic Acid Derivatives and Their Effects on Biological End‐points are Related to Changes in Histone Deacetylase and Erk1/2 Activities

Basic & clinical pharmacology & toxicology, 2011-09, Vol.109 (3), p.164-174

2011

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Brief report novel mechanism for valproate-induced teratogenicity

Birth defects research. A Clinical and molecular teratology, 2014-08, Vol.100 (8), p.592-597

2014

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Valproate Protein Binding Is Highly Variable in ICU Patients and Not Predicted by Total Serum Concentrations: A Case Series and Literature Review

Pharmacotherapy, 2017-04, Vol.37 (4), p.500-508

2017

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Novel potential of metformin on valproic acid‐induced autism spectrum disorder in rats: involvement of antioxidant defence system

Fundamental & clinical pharmacology, 2020-12, Vol.34 (6), p.650-661

2020

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A systematic review of population pharmacokinetics of valproic acid

British journal of clinical pharmacology, 2018-05, Vol.84 (5), p.816-834

Methaneethorn, Janthima

2018

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A novel and nonderivatization method for the determination of valproic acid in human serum by two‐dimensional liquid chromatography

Biomedical chromatography, 2020-01, Vol.34 (1), p.e4695-n/a

2020

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Correlation of drug dose estimated from national prescription registers with mean blood level of antiseizure medication in pregnancy

Pharmacoepidemiology and drug safety, 2024-06, Vol.33 (6), p.e5811-n/a

2024

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Characterisation, in‐vitro and in‐vivo evaluation of valproic acid‐loaded nanoemulsion for improved brain bioavailability

Journal of pharmacy and pharmacology, 2017-11, Vol.69 (11), p.1447-1457

2017

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Early Exposure of Fosphenytoin, Levetiracetam, and Valproic Acid After High‐Dose Intravenous Administration in Young Children With Benzodiazepine‐Refractory Status Epilepticus

Journal of clinical pharmacology, 2021-06, Vol.61 (6), p.763-768

2021

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Embryonic exposure to valproic acid affects the histaminergic system and the social behaviour of adult zebrafish (Danio rerio)

British journal of pharmacology, 2018-03, Vol.175 (5), p.797-809

2018

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Repurposing Valproate, Enteral Clonidine, and Phenobarbital for Comfort in Adult ICU Patients: A Literature Review with Practical Considerations

Pharmacotherapy, 2017-10, Vol.37 (10), p.1309-1321

2017

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Treatment with the combination of clavulanic acid and valproic acid led to recovery of neuronal and behavioral deficits in an epilepsy rat model

Fundamental & clinical pharmacology, 2021-12, Vol.35 (6), p.1032-1044

2021

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Changes in antiepileptic drug prescriptions over a decade in childbearing women in Lombardy region, Italy

British journal of clinical pharmacology, 2022-03, Vol.88 (3), p.1152-1158

2022

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No Pharmacokinetic Interaction Between Lacosamide and Valproic Acid in Healthy Volunteers

Journal of clinical pharmacology, 2012-11, Vol.52 (11), p.1739-1748

2012

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Melatonin attenuates branch chain fatty acid induced apoptosis mediated neurodegeneration

Environmental toxicology, 2021-04, Vol.36 (4), p.491-505

2021

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Risk Factors for Valproic Acid‐induced Hyperammonaemia in Chinese Paediatric Patients with Epilepsy

Basic & clinical pharmacology & toxicology, 2018-11, Vol.123 (5), p.628-634

2018

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Betaine ameliorates prenatal valproic‐acid‐induced autism‐like behavioral abnormalities in mice by promoting homocysteine metabolism

Psychiatry and clinical neurosciences, 2019-06, Vol.73 (6), p.317-322

2019

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ThemaValproic Acid - Pharmacology

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Clinical implications of trials investigating drug‐drug interactions between cannabidiol and enzyme inducers or inhibitors or common antiseizure drugs

Associations of CYP2C9 and CYP2A6 Polymorphisms with the Concentrations of Valproate and its Hepatotoxin Metabolites and Valproate‐Induced Hepatotoxicity

Effect of Age, Comedications, and CYP3A4/5 Polymorphisms on Perampanel Exposure in Chinese Pediatric Patients With Epilepsy

Effects of long-term antiepileptic drug monotherapy on vascular risk factors and atherosclerosis

Intentional use of carbapenem antibiotics for valproic acid toxicity: A case report

Interactions between cannabidiol and commonly used antiepileptic drugs

Dravet syndrome: Treatment options and management of prolonged seizures

Flucloxacillin instantly decreases serum levels of valproic acid: A case report

The Teratogenic Potencies of Valproic Acid Derivatives and Their Effects on Biological End‐points are Related to Changes in Histone Deacetylase and Erk1/2 Activities

Brief report novel mechanism for valproate-induced teratogenicity

Valproate Protein Binding Is Highly Variable in ICU Patients and Not Predicted by Total Serum Concentrations: A Case Series and Literature Review

Novel potential of metformin on valproic acid‐induced autism spectrum disorder in rats: involvement of antioxidant defence system

A systematic review of population pharmacokinetics of valproic acid

A novel and nonderivatization method for the determination of valproic acid in human serum by two‐dimensional liquid chromatography

Correlation of drug dose estimated from national prescription registers with mean blood level of antiseizure medication in pregnancy

Characterisation, in‐vitro and in‐vivo evaluation of valproic acid‐loaded nanoemulsion for improved brain bioavailability

Early Exposure of Fosphenytoin, Levetiracetam, and Valproic Acid After High‐Dose Intravenous Administration in Young Children With Benzodiazepine‐Refractory Status Epilepticus

Embryonic exposure to valproic acid affects the histaminergic system and the social behaviour of adult zebrafish (Danio rerio)

Repurposing Valproate, Enteral Clonidine, and Phenobarbital for Comfort in Adult ICU Patients: A Literature Review with Practical Considerations

Treatment with the combination of clavulanic acid and valproic acid led to recovery of neuronal and behavioral deficits in an epilepsy rat model

Changes in antiepileptic drug prescriptions over a decade in childbearing women in Lombardy region, Italy

No Pharmacokinetic Interaction Between Lacosamide and Valproic Acid in Healthy Volunteers

Melatonin attenuates branch chain fatty acid induced apoptosis mediated neurodegeneration

Risk Factors for Valproic Acid‐induced Hyperammonaemia in Chinese Paediatric Patients with Epilepsy

Betaine ameliorates prenatal valproic‐acid‐induced autism‐like behavioral abnormalities in mice by promoting homocysteine metabolism

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