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Power gains by using external information in clinical trials are typically not possible when requiring strict type I error control

Biometrical journal, 2020-03, Vol.62 (2), p.361-374

2020

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Exploratory identification of predictive biomarkers in randomized trials with normal endpoints

Statistics in medicine, 2020-03, Vol.39 (7), p.923-939

2020

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Robust incorporation of historical information with known type I error rate inflation

Biometrical journal, 2024-01, Vol.66 (1), p.e2200322-n/a

2024

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Simulating and reporting frequentist operating characteristics of clinical trials that borrow external information: Towards a fair comparison in case of one‐arm and hybrid control two‐arm trials

Pharmaceutical statistics : the journal of the pharmaceutical industry, 2024-01, Vol.23 (1), p.4-19

2024

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Comments on “Incorporating historical two‐arm data in clinical trials with binary outcome: A practical approach” by Manuel Feißt, Johannes Krisam and Meinhard Kieser

Pharmaceutical statistics : the journal of the pharmaceutical industry, 2021-01, Vol.20 (1), p.196-198

Kopp‐Schneider, Annette

2021

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The design heatmap: A simple visualization of D‐optimality design problems

Biometrical journal, 2020-12, Vol.62 (8), p.2013-2031

2020

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Prediction accuracy and variable selection for penalized cause‐specific hazards models

Biometrical journal, 2018-03, Vol.60 (2), p.288-306

2018

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Multiple‐rater kappas for binary data: Models and interpretation

Biometrical journal, 2018-03, Vol.60 (2), p.381-394

2018

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Monitoring futility and efficacy in phase II trials with Bayesian posterior distributions—A calibration approach

Biometrical journal, 2019-05, Vol.61 (3), p.488-502

2019

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Performance of phase‐I dose finding designs with and without a run‐in intra‐patient dose escalation stage

Pharmaceutical statistics : the journal of the pharmaceutical industry, 2023-03, Vol.22 (2), p.236-247

2023

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Addressing small sample size bias in multiple‐biomarker trials: Inclusion of biomarker‐negative patients and Firth correction

Biometrical journal, 2018-03, Vol.60 (2), p.275-287

2018

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Clustering of samples and variables with mixed-type data

PloS one, 2017-11, Vol.12 (11), p.e0188274-e0188274

2017

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Optimizing expert and patient input in pediatric trial design: Lessons learned and recommendations from a collaboration between conect4children and European Patient‐CEntric ClinicAl TRial PLatforms

Clinical and translational science, 2023-08, Vol.16 (8), p.1458-1468

2023

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Methods and open-source toolkit for analyzing and visualizing challenge results

Scientific reports, 2021-01, Vol.11 (1), p.2369-2369, Article 2369

2021

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Magnetic Resonance Imaging Detects Changes in Structure and Perfusion, and Response to Therapy in Early Cystic Fibrosis Lung Disease

American journal of respiratory and critical care medicine, 2014-04, Vol.189 (8), p.956-965

2014

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“ToxRTool”, a new tool to assess the reliability of toxicological data

Toxicology letters, 2009-09, Vol.189 (2), p.138-144

2009

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Histone Deacetylase 8 in Neuroblastoma Tumorigenesis

Clinical cancer research, 2009-01, Vol.15 (1), p.91-99

2009

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The German sickle cell disease registry reveals a surprising risk of acute splenic sequestration and an increased transfusion requirement in patients with compound heterozygous sickle cell disease HbS /β‐thalassaemia and no or low HbA expression

European journal of haematology, 2024-06, Vol.113 (4), p.501-509

2024

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Protocol of the VICTORIA study: personalized vitamin D supplementation for reducing or preventing fatigue and enhancing quality of life of patients with colorectal tumor - randomized intervention trial

BMC cancer, 2020-08, Vol.20 (1), p.739-739, Article 739

2020

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Effects of radiofrequency electromagnetic fields (RF EMF) on cancer in laboratory animal studies

Environment international, 2022-03, Vol.161, p.107106-107106

2022

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HDAC5 and HDAC9 in Medulloblastoma: Novel Markers for Risk Stratification and Role in Tumor Cell Growth

Clinical cancer research, 2010-06, Vol.16 (12), p.3240-3252

2010

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Summarizing EC50 estimates from multiple dose-response experiments: A comparison of a meta-analysis strategy to a mixed-effects model approach

Biometrical journal, 2014-05, Vol.56 (3), p.493-512

2014

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Spectral organ fingerprints for machine learning-based intraoperative tissue classification with hyperspectral imaging in a porcine model

Scientific reports, 2022-06, Vol.12 (1), p.11028-14, Article 11028

2022

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Power gains by using external information in clinical trials are typically not possible when requiring strict type I error control

Exploratory identification of predictive biomarkers in randomized trials with normal endpoints

Robust incorporation of historical information with known type I error rate inflation

Simulating and reporting frequentist operating characteristics of clinical trials that borrow external information: Towards a fair comparison in case of one‐arm and hybrid control two‐arm trials

Comments on “Incorporating historical two‐arm data in clinical trials with binary outcome: A practical approach” by Manuel Feißt, Johannes Krisam and Meinhard Kieser

The design heatmap: A simple visualization of D‐optimality design problems

Prediction accuracy and variable selection for penalized cause‐specific hazards models

Multiple‐rater kappas for binary data: Models and interpretation

Monitoring futility and efficacy in phase II trials with Bayesian posterior distributions—A calibration approach

Performance of phase‐I dose finding designs with and without a run‐in intra‐patient dose escalation stage

Addressing small sample size bias in multiple‐biomarker trials: Inclusion of biomarker‐negative patients and Firth correction

Clustering of samples and variables with mixed-type data

Optimizing expert and patient input in pediatric trial design: Lessons learned and recommendations from a collaboration between conect4children and European Patient‐CEntric ClinicAl TRial PLatforms

Why rankings of biomedical image analysis competitions should be interpreted with care

Methods and open-source toolkit for analyzing and visualizing challenge results

Magnetic Resonance Imaging Detects Changes in Structure and Perfusion, and Response to Therapy in Early Cystic Fibrosis Lung Disease

CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma

“ToxRTool”, a new tool to assess the reliability of toxicological data

Histone Deacetylase 8 in Neuroblastoma Tumorigenesis

The German sickle cell disease registry reveals a surprising risk of acute splenic sequestration and an increased transfusion requirement in patients with compound heterozygous sickle cell disease HbS /β‐thalassaemia and no or low HbA expression

Protocol of the VICTORIA study: personalized vitamin D supplementation for reducing or preventing fatigue and enhancing quality of life of patients with colorectal tumor - randomized intervention trial

Effects of radiofrequency electromagnetic fields (RF EMF) on cancer in laboratory animal studies

HDAC5 and HDAC9 in Medulloblastoma: Novel Markers for Risk Stratification and Role in Tumor Cell Growth

Summarizing EC50 estimates from multiple dose-response experiments: A comparison of a meta-analysis strategy to a mixed-effects model approach

Spectral organ fingerprints for machine learning-based intraoperative tissue classification with hyperspectral imaging in a porcine model

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