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AMPK activation by metformin protects against pulmonary hypertension in rats and relaxes isolated human pulmonary artery

European journal of pharmacology, 2023-05, Vol.946, p.175579-175579, Article 175579

2023

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Immunity and inflammation in pulmonary arterial hypertension: From pathophysiology mechanisms to treatment perspective

Pharmacological research, 2022-06, Vol.180, p.106238-106238, Article 106238

2022

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Win Statistics in Pulmonary Arterial Hypertension Clinical Trials

American journal of respiratory and critical care medicine, 2023-12, Vol.208 (11), p.1231

2023

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Disease characteristics, treatments, and outcomes of patients with pulmonary arterial hypertension treated with selexipag in real-world settings from the SPHERE registry (SelexiPag: tHe usErs dRug rEgistry)

The Journal of heart and lung transplantation, 2024-02, Vol.43 (2), p.272-283

2024

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The role of riociguat in combination therapies for pulmonary arterial hypertension

Respiratory medicine, 2023-05, Vol.211, p.107196-107196, Article 107196

2023

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Ambrisentan for in pediatric pulmonary arterial hypertension: A cost‐utility analysis

Pediatric pulmonology, 2023-05, Vol.58 (5), p.1562-1568

2023

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Diagnosis and Treatment of Pulmonary Arterial Hypertension: A Review

JAMA : the journal of the American Medical Association, 2022-04, Vol.327 (14), p.1379

2022

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Treprostinil treatment decreases circulating platelet microvesicles and their procoagulant activity in pediatric pulmonary hypertension

Pediatric pulmonology, 2019-01, Vol.54 (1), p.66-72

2019

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Activation of the Metabolic Master Regulator PPARγ: A Potential PIOneering Therapy for Pulmonary Arterial Hypertension

American journal of respiratory cell and molecular biology, 2020-02, Vol.62 (2), p.143-156

2020

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Aggressive Afterload Lowering to Improve the Right Ventricle: A New Target for Medical Therapy in Pulmonary Arterial Hypertension?

American journal of respiratory and critical care medicine, 2022-04, Vol.205 (7), p.751-760

2022

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Triple vasodilator therapy in pulmonary arterial hypertension associated with congenital heart disease

Heart (British Cardiac Society), 2024-03, Vol.110 (5), p.346

2024

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Corosolic acid attenuates platelet-derived growth factor signaling in macrophages and smooth muscle cells of pulmonary arterial hypertension

European journal of pharmacology, 2024-06, Vol.973, p.176564-176564, Article 176564

2024

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Prostaglandin I 2 Therapy Promotes Regulatory T Cell Generation in Patients with Pulmonary Arterial Hypertension

American journal of respiratory and critical care medicine, 2023-09, Vol.208 (6), p.737

2023

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Continued Progress in Therapy for Pulmonary Arterial Hypertension

The New England journal of medicine, 2023-04, Vol.388 (16), p.1524-1526

2023

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POINT: Should the Use of Upfront Triple Combination Therapy Be Standard of Care in Pulmonary Arterial Hypertension? Yes

Chest, 2024-03, Vol.165 (3), p.492-494

2024

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Blockade of JAK2 protects mice against hypoxia‐induced pulmonary arterial hypertension by repressing pulmonary arterial smooth muscle cell proliferation

Cell proliferation, 2020-02, Vol.53 (2), p.e12742-n/a

2020

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Additive protective effects of sacubitril/valsartan and bosentan on vascular remodelling in experimental pulmonary hypertension

Cardiovascular research, 2021-04, Vol.117 (5), p.1391-1401

2021

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FDA approves Merck & Co's pulmonary arterial hypertension drug sotatercept

Nature reviews. Drug discovery, 2024-05, Vol.23 (5), p.327-327

Kingwell, Katie

2024

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Spermidine attenuates monocrotaline-induced pulmonary arterial hypertension in rats by inhibiting purine metabolism and polyamine synthesis-associated vascular remodeling

International immunopharmacology, 2024-05, Vol.132, p.111946-111946, Article 111946

2024

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Combined pre- and post-capillary pulmonary hypertension in left heart disease

Heart failure reviews, 2023-01, Vol.28 (1), p.137-148

2023

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Canagliflozin inhibits PASMCs proliferation via regulating SGLT1/AMPK signaling and attenuates artery remodeling in MCT-induced pulmonary arterial hypertension

Biomedicine & pharmacotherapy, 2024-05, Vol.174, p.116505-116505, Article 116505

2024

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Two polymorphic gene loci associated with treprostinil dose in pulmonary arterial hypertension

Pharmacogenetics and genomics, 2022-06, Vol.32 (4), p.144

2022

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Counterpoint: Should the Use of Upfront Triple Combination Therapy Be Standard of Care in Pulmonary Arterial Hypertension? No

Chest, 2024-03, Vol.165 (3), p.494-496

Sahay, Sandeep

2024

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Pharmacological management of connective tissue disease-associated pulmonary arterial hypertension

Expert opinion on pharmacotherapy, 2023-12, Vol.24 (18), p.2101-2115

2023

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Scleroderma pulmonary arterial hypertension: the same as idiopathic pulmonary arterial hypertension?

Current opinion in pulmonary medicine, 2023-09, Vol.29 (5), p.380

2023

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AMPK activation by metformin protects against pulmonary hypertension in rats and relaxes isolated human pulmonary artery

Immunity and inflammation in pulmonary arterial hypertension: From pathophysiology mechanisms to treatment perspective

Win Statistics in Pulmonary Arterial Hypertension Clinical Trials

Disease characteristics, treatments, and outcomes of patients with pulmonary arterial hypertension treated with selexipag in real-world settings from the SPHERE registry (SelexiPag: tHe usErs dRug rEgistry)

The role of riociguat in combination therapies for pulmonary arterial hypertension

Ambrisentan for in pediatric pulmonary arterial hypertension: A cost‐utility analysis

Diagnosis and Treatment of Pulmonary Arterial Hypertension: A Review

Treprostinil treatment decreases circulating platelet microvesicles and their procoagulant activity in pediatric pulmonary hypertension

Activation of the Metabolic Master Regulator PPARγ: A Potential PIOneering Therapy for Pulmonary Arterial Hypertension

Aggressive Afterload Lowering to Improve the Right Ventricle: A New Target for Medical Therapy in Pulmonary Arterial Hypertension?

Triple vasodilator therapy in pulmonary arterial hypertension associated with congenital heart disease

Corosolic acid attenuates platelet-derived growth factor signaling in macrophages and smooth muscle cells of pulmonary arterial hypertension

Prostaglandin I 2 Therapy Promotes Regulatory T Cell Generation in Patients with Pulmonary Arterial Hypertension

Continued Progress in Therapy for Pulmonary Arterial Hypertension

POINT: Should the Use of Upfront Triple Combination Therapy Be Standard of Care in Pulmonary Arterial Hypertension? Yes

Blockade of JAK2 protects mice against hypoxia‐induced pulmonary arterial hypertension by repressing pulmonary arterial smooth muscle cell proliferation

Additive protective effects of sacubitril/valsartan and bosentan on vascular remodelling in experimental pulmonary hypertension

FDA approves Merck & Co's pulmonary arterial hypertension drug sotatercept

Spermidine attenuates monocrotaline-induced pulmonary arterial hypertension in rats by inhibiting purine metabolism and polyamine synthesis-associated vascular remodeling

Combined pre- and post-capillary pulmonary hypertension in left heart disease

Canagliflozin inhibits PASMCs proliferation via regulating SGLT1/AMPK signaling and attenuates artery remodeling in MCT-induced pulmonary arterial hypertension

Two polymorphic gene loci associated with treprostinil dose in pulmonary arterial hypertension

Counterpoint: Should the Use of Upfront Triple Combination Therapy Be Standard of Care in Pulmonary Arterial Hypertension? No

Pharmacological management of connective tissue disease-associated pulmonary arterial hypertension

Scleroderma pulmonary arterial hypertension: the same as idiopathic pulmonary arterial hypertension?

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