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RNA antitoxins

Current opinion in microbiology, 2007-04, Vol.10 (2), p.117-124

2007

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TADB 2.0: an updated database of bacterial type II toxin-antitoxin loci

Nucleic acids research, 2018-01, Vol.46 (D1), p.D749-D753

2018

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Mechanisms of bacterial persistence during stress and antibiotic exposure

Science (American Association for the Advancement of Science), 2016-12, Vol.354 (6318), p.1390-1390

2016

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Type VI secretion delivers bacteriolytic effectors to target cells

Nature (London), 2011-07, Vol.475 (7356), p.343-347

2011

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The Toxin-Antitoxin System DarTG Catalyzes Reversible ADP-Ribosylation of DNA

Molecular cell, 2016-12, Vol.64 (6), p.1109-1116

2016

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Laboratory evolution of artificially expanded DNA gives redesignable aptamers that target the toxic form of anthrax protective antigen

Nucleic acids research, 2016-11, Vol.44 (20), p.9565

2016

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Assessment of an Anti-Alpha-Toxin Monoclonal Antibody for Prevention and Treatment of Staphylococcus aureus-Induced Pneumonia

Antimicrobial Agents and Chemotherapy, 2014-02, Vol.58 (2), p.1108-1117

2014

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Pseudomonas aeruginosa Effector ExoS Inhibits ROS Production in Human Neutrophils

Cell host & microbe, 2017-05, Vol.21 (5), p.611-618.e5

2017

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Is There Potential for Repurposing Statins as Novel Antimicrobials?

Antimicrobial agents and chemotherapy, 2016-09, Vol.60 (9), p.5111-5121

2016

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Functional defects in Clostridium difficile TcdB toxin uptake identify CSPG4 receptor-binding determinants

The Journal of biological chemistry, 2017-10, Vol.292 (42), p.17290-17301

2017

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High-Resolution Size-Discrimination of Single Nonionic Synthetic Polymers with a Highly Charged Biological Nanopore

ACS nano, 2015-06, Vol.9 (6), p.6443-6449

2015

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Staphylococcal alpha‐phenol soluble modulins contribute to neutrophil lysis after phagocytosis

Cellular microbiology, 2013-08, Vol.15 (8), p.1427-1437

2013

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Inhibition of Staphylococcus aureus biofilm-forming functional amyloid by molecular tweezers

Cell chemical biology, 2021-09, Vol.28 (9), p.1310-1320.e5

2021

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YeeU enhances the bundling of cytoskeletal polymers of MreB and FtsZ, antagonizing the CbtA (YeeV) toxicity in Escherichia coli

Molecular microbiology, 2012-06, Vol.84 (5), p.979-989

2012

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Mechanistic insights into type I toxin antitoxin systems in Helicobacter pylori: the importance of mRNA folding in controlling toxin expression

Nucleic acids research, 2017-05, Vol.45 (8), p.4782

2017

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Castanea sativa (European Chestnut) Leaf Extracts Rich in Ursene and Oleanene Derivatives Block Staphylococcus aureus Virulence and Pathogenesis without Detectable Resistance

PloS one, 2015-08, Vol.10 (8), p.e0136486

2015

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Discovery of Antivirulence Agents against Methicillin-Resistant Staphylococcus aureus

Antimicrobial Agents and Chemotherapy, 2013-08, Vol.57 (8), p.3645-3652

2013

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Novel humanized anti-PcrV monoclonal antibody COT-143 protects mice from lethal Pseudomonas aeruginosa infection via inhibition of toxin translocation by the type III secretion system

Antimicrobial agents and chemotherapy, 2024-10, Vol.68 (10), p.e0069424

2024

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Cyclophilin-Facilitated Membrane Translocation as Pharmacological Target to Prevent Intoxication of Mammalian Cells by Binary Clostridial Actin ADP-Ribosylated Toxins

Journal of molecular biology, 2015-03, Vol.427 (6), p.1224-1238

2015

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Structural and functional studies of the Mycobacterium tuberculosis VapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides

Nucleic acids research, 2015-09, Vol.43 (15), p.7624-7637

2015

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Serum anti-toxin B antibody correlates with protection from recurrent Clostridium difficile infection (CDI)

Vaccine, 2010-01, Vol.28 (4), p.965-969

2010

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Lactobacillus reuteri-produced cyclic dipeptides quench agr-mediated expression of toxic shock syndrome toxin-1 in staphylococci

Proceedings of the National Academy of Sciences - PNAS, 2011-02, Vol.108 (8), p.3360-3365

2011

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Targeting NLRP3 and Staphylococcal pore‐forming toxin receptors in human‐induced pluripotent stem cell‐derived macrophages

Journal of leukocyte biology, 2020-09, Vol.108 (3), p.967-981

2020

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Structural and Functional Study of the Klebsiella pneumoniae VapBC Toxin–Antitoxin System, Including the Development of an Inhibitor That Activates VapC

Journal of medicinal chemistry, 2020-11, Vol.63 (22), p.13669-13679

2020

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The Saccharomyces boulardii CNCM I-745 strain shows protective effects against the B. anthracis LT toxin

Toxins, 2015-10, Vol.7 (11), p.4455-4467

2015

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RNA antitoxins

TADB 2.0: an updated database of bacterial type II toxin-antitoxin loci

Mechanisms of bacterial persistence during stress and antibiotic exposure

Type VI secretion delivers bacteriolytic effectors to target cells

The Toxin-Antitoxin System DarTG Catalyzes Reversible ADP-Ribosylation of DNA

Laboratory evolution of artificially expanded DNA gives redesignable aptamers that target the toxic form of anthrax protective antigen

Assessment of an Anti-Alpha-Toxin Monoclonal Antibody for Prevention and Treatment of Staphylococcus aureus-Induced Pneumonia

Pseudomonas aeruginosa Effector ExoS Inhibits ROS Production in Human Neutrophils

Is There Potential for Repurposing Statins as Novel Antimicrobials?

Functional defects in Clostridium difficile TcdB toxin uptake identify CSPG4 receptor-binding determinants

High-Resolution Size-Discrimination of Single Nonionic Synthetic Polymers with a Highly Charged Biological Nanopore

Staphylococcal alpha‐phenol soluble modulins contribute to neutrophil lysis after phagocytosis

Inhibition of Staphylococcus aureus biofilm-forming functional amyloid by molecular tweezers

YeeU enhances the bundling of cytoskeletal polymers of MreB and FtsZ, antagonizing the CbtA (YeeV) toxicity in Escherichia coli

Mechanistic insights into type I toxin antitoxin systems in Helicobacter pylori: the importance of mRNA folding in controlling toxin expression

Castanea sativa (European Chestnut) Leaf Extracts Rich in Ursene and Oleanene Derivatives Block Staphylococcus aureus Virulence and Pathogenesis without Detectable Resistance

Discovery of Antivirulence Agents against Methicillin-Resistant Staphylococcus aureus

Novel humanized anti-PcrV monoclonal antibody COT-143 protects mice from lethal Pseudomonas aeruginosa infection via inhibition of toxin translocation by the type III secretion system

Cyclophilin-Facilitated Membrane Translocation as Pharmacological Target to Prevent Intoxication of Mammalian Cells by Binary Clostridial Actin ADP-Ribosylated Toxins

Structural and functional studies of the Mycobacterium tuberculosis VapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides

Serum anti-toxin B antibody correlates with protection from recurrent Clostridium difficile infection (CDI)

Lactobacillus reuteri-produced cyclic dipeptides quench agr-mediated expression of toxic shock syndrome toxin-1 in staphylococci

Targeting NLRP3 and Staphylococcal pore‐forming toxin receptors in human‐induced pluripotent stem cell‐derived macrophages

Structural and Functional Study of the Klebsiella pneumoniae VapBC Toxin–Antitoxin System, Including the Development of an Inhibitor That Activates VapC

The Saccharomyces boulardii CNCM I-745 strain shows protective effects against the B. anthracis LT toxin

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