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Chemical Synthesis of Activity‐Based E2‐Ubiquitin Probes for the Structural Analysis of E3 Ligase‐Catalyzed Transthiolation

Angewandte Chemie International Edition, 2021-07, Vol.60 (31), p.17171-17177

International ed. in English, 2021

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An E1‐Catalyzed Chemoenzymatic Strategy to Isopeptide‐N‐Ethylated Deubiquitylase‐Resistant Ubiquitin Probes

Angewandte Chemie International Edition, 2020-08, Vol.59 (32), p.13496-13501

International ed. in English, 2020

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Acyl azide modification of the ubiquitin C-terminus enables DUB capture

Chemical communications (Cambridge, England), 2023-01, Vol.59 (1), p.1333-1336

2023

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The Ubiquitin Enigma: Progress in the Detection and Chemical Synthesis of Branched Ubiquitin Chains

Chembiochem : a European journal of chemical biology, 2020-12, Vol.21 (23), p.3313-3318

2020

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Efficient Chemical Synthesis and Folding of Mirror‐Image Tropomyosin Receptor Kinase A Using the Strategy of Removable Glycosylation Modification

Chinese journal of chemistry, 2024-10, Vol.42 (19), p.2316-2322

2024

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Thioester‐Assisted Sortase‐A‐Mediated Ligation

Angewandte Chemie International Edition, 2022-07, Vol.61 (28), p.e202201887-n/a

International ed. in English, 2022

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Cysteine-Aminoethylation-Assisted Chemical Ubiquitination of Recombinant Histones

Journal of the American Chemical Society, 2019-02, Vol.141 (8), p.3654-3663

2019

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The expedient, CAET-assisted synthesis of dual-monoubiquitinated histone H3 enables evaluation of its interaction with DNMT1

Chemical science (Cambridge), 2023-05, Vol.14 (21), p.5681-5688

2023

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One-Pot Synthesis of a Bis-Thio-Acetone Linked Ubiquitinated Histones Using 1,3-Dibromoacetone

Journal of organic chemistry, 2020-12, Vol.85 (23), p.15631-15637

2020

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Efficient Semi‐Synthesis of Atypical Ubiquitin Chains and Ubiquitin‐Based Probes Forged by Thioether Isopeptide Bonds

Chemistry : a European journal, 2019-12, Vol.25 (72), p.16668-16675

2019

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Catalyst free hydrazone ligation for protein labeling and modification using electron-deficient benzaldehyde reagents

Organic & biomolecular chemistry, 2018, Vol.16 (38), p.7036-7040

2018

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Cell-Permeable Stimuli-Responsive Ubiquitin Probe for Time-Resolved Monitoring of Substrate Ubiquitination in Live Cells

JACS Au, 2023-10, Vol.3 (10), p.2873-2882

2023

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Chemical Synthesis of Post-Translationally Modified H2AX Reveals Redundancy in Interplay between Histone Phosphorylation, Ubiquitination, and Methylation on the Binding of 53BP1 with Nucleosomes

Journal of the American Chemical Society, 2022-10, Vol.144 (40), p.18329-18337

2022

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Chemical synthesis of on demand-activated SUMO-based probe by a photocaged glycine-assisted strategy

Bioorganic & medicinal chemistry letters, 2023-10, Vol.94, p.129460-129460, Article 129460

2023

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Chemical Synthesis of K48-Linked Diubiquitin by Incorporation of a Lysine-Linked Auxiliary Handle

European journal of organic chemistry, 2016-05, Vol.2016 (15), p.2665-2670

2016

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Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes

Nature structural & molecular biology, 2024-02, Vol.31 (2), p.300-310

2024

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An E1‐Catalyzed Chemoenzymatic Strategy to Isopeptide‐N‐Ethylated Deubiquitylase‐Resistant Ubiquitin Probes

Angewandte Chemie, 2020-08, Vol.132 (32), p.13598-13603

2020

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Semi-synthesis of K27-linked-mixed-triubiquitin chains through a combination of enzymatic reaction with CAACU strategy

Tetrahedron letters, 2021-05, Vol.71, p.153000, Article 153000

2021

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The Study of the Chemical Synthesis and Preparation of Histone with Post- Translational Modifications

Current organic synthesis, 2015-01, Vol.12 (2), p.150-162

2015

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Acid-sensitive auxiliary assisted atypical diubiquitin synthesis exploiting thiol-ene coupling

Tetrahedron letters, 2019-10, Vol.60 (41), p.151123, Article 151123

2019

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Efficient semi-synthesis of ubiquitin-7-amino-4-methylcoumarin

Tetrahedron, 2018-07, Vol.74 (28), p.3931-3935

2018

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Efficient chemical synthesis for the analogue of ubiquitin-based probe Ub–AMC with native bioactivity

RSC advances, 2016-01, Vol.6 (53), p.47926-47930

2016

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Thioester‐Assisted Sortase‐A‐Mediated Ligation

Angewandte Chemie, 2022-07, Vol.134 (28), p.n/a

2022

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Chemical Synthesis of Activity‐Based E2‐Ubiquitin Probes for the Structural Analysis of E3 Ligase‐Catalyzed Transthiolation

Angewandte Chemie, 2021-07, Vol.133 (31), p.17308-17314

2021

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Promotion of RNF168-Mediated Nucleosomal H2A Ubiquitylation by Structurally defined K63-Polyubiquitylated Linker Histone H1

Angewandte Chemie International Edition, 2024-10, p.e202413651

2024

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Chemical Synthesis of Activity‐Based E2‐Ubiquitin Probes for the Structural Analysis of E3 Ligase‐Catalyzed Transthiolation

An E1‐Catalyzed Chemoenzymatic Strategy to Isopeptide‐N‐Ethylated Deubiquitylase‐Resistant Ubiquitin Probes

Acyl azide modification of the ubiquitin C-terminus enables DUB capture

The Ubiquitin Enigma: Progress in the Detection and Chemical Synthesis of Branched Ubiquitin Chains

Efficient Chemical Synthesis and Folding of Mirror‐Image Tropomyosin Receptor Kinase A Using the Strategy of Removable Glycosylation Modification

Thioester‐Assisted Sortase‐A‐Mediated Ligation

Cysteine-Aminoethylation-Assisted Chemical Ubiquitination of Recombinant Histones

The expedient, CAET-assisted synthesis of dual-monoubiquitinated histone H3 enables evaluation of its interaction with DNMT1

One-Pot Synthesis of a Bis-Thio-Acetone Linked Ubiquitinated Histones Using 1,3-Dibromoacetone

Efficient Semi‐Synthesis of Atypical Ubiquitin Chains and Ubiquitin‐Based Probes Forged by Thioether Isopeptide Bonds

Catalyst free hydrazone ligation for protein labeling and modification using electron-deficient benzaldehyde reagents

Cell-Permeable Stimuli-Responsive Ubiquitin Probe for Time-Resolved Monitoring of Substrate Ubiquitination in Live Cells

Chemical Synthesis of Post-Translationally Modified H2AX Reveals Redundancy in Interplay between Histone Phosphorylation, Ubiquitination, and Methylation on the Binding of 53BP1 with Nucleosomes

Chemical synthesis of on demand-activated SUMO-based probe by a photocaged glycine-assisted strategy

Chemical Synthesis of K48-Linked Diubiquitin by Incorporation of a Lysine-Linked Auxiliary Handle

Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes

An E1‐Catalyzed Chemoenzymatic Strategy to Isopeptide‐N‐Ethylated Deubiquitylase‐Resistant Ubiquitin Probes

Semi-synthesis of K27-linked-mixed-triubiquitin chains through a combination of enzymatic reaction with CAACU strategy

The Study of the Chemical Synthesis and Preparation of Histone with Post- Translational Modifications

Acid-sensitive auxiliary assisted atypical diubiquitin synthesis exploiting thiol-ene coupling

Efficient semi-synthesis of ubiquitin-7-amino-4-methylcoumarin

Efficient chemical synthesis for the analogue of ubiquitin-based probe Ub–AMC with native bioactivity

Thioester‐Assisted Sortase‐A‐Mediated Ligation

Chemical Synthesis of Activity‐Based E2‐Ubiquitin Probes for the Structural Analysis of E3 Ligase‐Catalyzed Transthiolation

Promotion of RNF168-Mediated Nucleosomal H2A Ubiquitylation by Structurally defined K63-Polyubiquitylated Linker Histone H1

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