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Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency

Nature (London), 2020-12, Vol.588 (7838), p.459-465

2020

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Stages of pTDP-43 pathology in amyotrophic lateral sclerosis

Annals of neurology, 2013-07, Vol.74 (1), p.20-38

2013

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RNA-binding proteins with prion-like domains in health and disease

Biochemical journal, 2017-04, Vol.474 (8), p.1417-1438

2017

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TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response

PLoS genetics, 2019-05, Vol.15 (5), p.e1007947-e1007947

2019

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TDP-43 pathology and memory impairment in elders without pathologic diagnoses of AD or FTLD

Neurology, 2017-02, Vol.88 (7), p.653

2017

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Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy

Nature neuroscience, 2018-03, Vol.21 (3), p.329

2018

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Distinct characteristics of limbic-predominant age-related TDP-43 encephalopathy in Lewy body disease

Acta neuropathologica, 2022-01, Vol.143 (1), p.15-31

2022

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C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy

Science translational medicine, 2020-09, Vol.12 (559)

2020

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Evaluation of TDP-43 proteinopathy and hippocampal sclerosis in relation to APOE ε4 haplotype status: a community-based cohort study

Lancet neurology, 2018-09, Vol.17 (9), p.773-781

2018

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Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated

Brain (London, England : 1878), 2018-07, Vol.141 (7), p.2181-2193

2018

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TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle

Nature (London), 2018-11, Vol.563 (7732), p.508-513

2018

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Limbic-predominant age-related TDP-43 encephalopathy, ADNC pathology, and cognitive decline in aging

Neurology, 2020-10, Vol.95 (14), p.e1951

2020

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In Vivo Diagnosis of Synucleinopathies: A Comparative Study of Skin Biopsy and RT-QuIC

Neurology, 2021-05, Vol.96 (20), p.e2513

2021

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Association of Cognition and Dementia With Neuropathologic Changes of Alzheimer Disease and Other Conditions in the Oldest Old

Neurology, 2022-09, Vol.99 (10), p.e1067

2022

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Mitigating a TDP-43 proteinopathy by targeting ataxin-2 using RNA-targeting CRISPR effector proteins

Nature communications, 2023-10, Vol.14 (1), p.6492-6492, Article 6492

2023

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Alternatively spliced ELAVL3 cryptic exon 4a causes ELAVL3 downregulation in ALS TDP-43 proteinopathy

Acta neuropathologica, 2024-06, Vol.147 (1), p.93, Article 93

2024

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Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients

Nature communications, 2014-09, Vol.5 (1), p.4824, Article 4824

2014

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Contribution of TDP and hippocampal sclerosis to hippocampal volume loss in older-old persons

Neurology, 2020-01, Vol.94 (2), p.e142

2020

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Pathological mechanisms underlying TDP-43 driven neurodegeneration in FTLD-ALS spectrum disorders

Human molecular genetics, 2013-10, Vol.22 (R1), p.R77-R87

2013

Volltextzugriff (PDF)

TDP-43 proteinopathy in ALS is triggered by loss of ASRGL1 and associated with HML-2 expression

Nature communications, 2024-05, Vol.15 (1), p.4163-4163, Article 4163

2024

Volltextzugriff (PDF)

Brain injection of α-synuclein induces multiple proteinopathies, gliosis, and a neuronal injury marker

The Journal of neuroscience, 2014-09, Vol.34 (37), p.12368-12378

2014

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TAR DNA-binding protein 43 and pathological subtype of Alzheimer's disease impact clinical features

Annals of neurology, 2015-11, Vol.78 (5), p.697-709

2015

Volltextzugriff (PDF)

Limbic‐predominant age‐related TDP‐43 encephalopathy neuropathologic change and microvascular pathologies in community‐dwelling older persons

Brain pathology (Zurich, Switzerland), 2021-05, Vol.31 (3), p.e12939-n/a

2021

Volltextzugriff (PDF)

Patterns of atrophy in pathologically confirmed dementias: a voxelwise analysis

Journal of neurology, neurosurgery and psychiatry, 2017-11, Vol.88 (11), p.908

2017

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Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report

Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency

Stages of pTDP-43 pathology in amyotrophic lateral sclerosis

RNA-binding proteins with prion-like domains in health and disease

TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response

TDP-43 pathology and memory impairment in elders without pathologic diagnoses of AD or FTLD

Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy

Distinct characteristics of limbic-predominant age-related TDP-43 encephalopathy in Lewy body disease

C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy

Evaluation of TDP-43 proteinopathy and hippocampal sclerosis in relation to APOE ε4 haplotype status: a community-based cohort study

Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated

TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle

Limbic-predominant age-related TDP-43 encephalopathy, ADNC pathology, and cognitive decline in aging

In Vivo Diagnosis of Synucleinopathies: A Comparative Study of Skin Biopsy and RT-QuIC

Association of Cognition and Dementia With Neuropathologic Changes of Alzheimer Disease and Other Conditions in the Oldest Old

Mitigating a TDP-43 proteinopathy by targeting ataxin-2 using RNA-targeting CRISPR effector proteins

Alternatively spliced ELAVL3 cryptic exon 4a causes ELAVL3 downregulation in ALS TDP-43 proteinopathy

Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients

Contribution of TDP and hippocampal sclerosis to hippocampal volume loss in older-old persons

Pathological mechanisms underlying TDP-43 driven neurodegeneration in FTLD-ALS spectrum disorders

TDP-43 proteinopathy in ALS is triggered by loss of ASRGL1 and associated with HML-2 expression

Brain injection of α-synuclein induces multiple proteinopathies, gliosis, and a neuronal injury marker

TAR DNA-binding protein 43 and pathological subtype of Alzheimer's disease impact clinical features

Limbic‐predominant age‐related TDP‐43 encephalopathy neuropathologic change and microvascular pathologies in community‐dwelling older persons

Patterns of atrophy in pathologically confirmed dementias: a voxelwise analysis

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