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Targeting dorsal root ganglia and primary sensory neurons for the treatment of chronic pain

Expert opinion on therapeutic targets, 2017-07, Vol.21 (7), p.695-703

2017

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Connexin-43 induces chemokine release from spinal cord astrocytes to maintain late-phase neuropathic pain in mice

Brain (London, England : 1878), 2014-08, Vol.137 (Pt 8), p.2193-2209

2014

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Inhibition of mechanical allodynia in neuropathic pain by TLR5-mediated A-fiber blockade

Nature medicine, 2015-11, Vol.21 (11), p.1326-1331

2015

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Monoclonal Antibody Targeting the Matrix Metalloproteinase 9 Prevents and Reverses Paclitaxel-Induced Peripheral Neuropathy in Mice

The journal of pain, 2019-05, Vol.20 (5), p.515-527

2019

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Neuropathic pain is constitutively suppressed in early life by anti-inflammatory neuroimmune regulation

The Journal of neuroscience, 2015-01, Vol.35 (2), p.457-466

2015

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Toll-like receptor 4 contributes to chronic itch, alloknesis, and spinal astrocyte activation in male mice

Pain (Amsterdam), 2016-04, Vol.157 (4), p.806-817

2016

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Paclitaxel-activated astrocytes produce mechanical allodynia in mice by releasing tumor necrosis factor-α and stromal-derived cell factor 1

Journal of neuroinflammation, 2019-11, Vol.16 (1), p.209-14, Article 209

2019

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TNF-alpha contributes to spinal cord synaptic plasticity and inflammatory pain: Distinct role of TNF receptor subtypes 1 and 2

Pain (Amsterdam), 2011-02, Vol.152 (2), p.419-427

2011

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SHANK3 Deficiency Impairs Heat Hyperalgesia and TRPV1 Signaling in Primary Sensory Neurons

Neuron (Cambridge, Mass.), 2016-12, Vol.92 (6), p.1279-1293

2016

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The inhibition of Kir2.1 potassium channels depolarizes spinal microglial cells, reduces their proliferation, and attenuates neuropathic pain

Glia, 2020-10, Vol.68 (10), p.2119-2135

2020

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Nociceptive neurons regulate innate and adaptive immunity and neuropathic pain through MyD88 adapter

Cell research, 2014-08, Vol.24 (11), p.1374-1377

2014

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Resolvin D3 controls mouse and human TRPV1-positive neurons and preclinical progression of psoriasis

Theranostics, 2020-01, Vol.10 (26), p.12111-12126

2020

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Transcriptional Profiling of Somatostatin Interneurons in the Spinal Dorsal Horn

Scientific reports, 2018-05, Vol.8 (1), p.6809-16, Article 6809

2018

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Lipoxin A4 inhibits microglial activation and reduces neuroinflammation and neuropathic pain after spinal cord hemisection

Journal of neuroinflammation, 2016-04, Vol.13 (1), p.75-75, Article 75

2016

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Dissociation and Culture of Adult Mouse Satellite Glial Cells

Bio-protocol, 2023-12, Vol.13 (24), p.e4906-e4906

2023

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Targeting Nociceptive Neurons and Transient Receptor Potential Channels for the Treatment of Migraine

International journal of molecular sciences, 2023-04, Vol.24 (9), p.7897

2023

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Peripheral serotonin receptor 2B and transient receptor potential channel 4 mediate pruritus to serotonergic antidepressants in mice

Journal of allergy and clinical immunology, 2018-10, Vol.142 (4), p.1349-1352.e16

2018

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β-arrestin-2 regulates NMDA receptor function in spinal lamina II neurons and duration of persistent pain

Nature communications, 2016-08, Vol.7 (1), p.12531-12531, Article 12531

2016

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Gene Expression Profiling of Cutaneous Injured and Non-Injured Nociceptors in SNI Animal Model of Neuropathic Pain

Scientific reports, 2017-08, Vol.7 (1), p.9367-11, Article 9367

2017

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Transient Receptor Potential Channel 4 Small-Molecule Inhibition Alleviates Migraine-Like Behavior in Mice

Frontiers in molecular neuroscience, 2021-11, Vol.14, p.765181-765181

2021

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Venom Peptide Toxins Targeting the Outer Pore Region of Transient Receptor Potential Vanilloid 1 in Pain: Implications for Analgesic Drug Development

International journal of molecular sciences, 2022-05, Vol.23 (10), p.5772

2022

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Distinct ASIC currents are expressed in rat putative nociceptors and are modulated by nerve injury

The Journal of physiology, 2006-10, Vol.576 (1), p.215-234

2006

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Unconventional Role of Caspase-6 in Spinal Microglia Activation and Chronic Pain

Mediators of inflammation, 2017-01, Vol.2017 (2017), p.1-8

2017

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Large A-Fiber Activity is Required for Microglial Proliferation and P38 MAPK Activation in the Spinal Cord: Different Effects of Resiniferatoxin and Bupivacaine on Spinal Microglial Changes after Spared Nerve Injury

Molecular pain, 2009-09, Vol.5 (1), p.53-53

2009

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Acute Morphine Activates Satellite Glial Cells and Up-Regulates IL-1β in Dorsal Root Ganglia in Mice via Matrix Metalloprotease-9

Molecular pain, 2012-03, Vol.8 (1), p.18-18

2012

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Targeting dorsal root ganglia and primary sensory neurons for the treatment of chronic pain

Connexin-43 induces chemokine release from spinal cord astrocytes to maintain late-phase neuropathic pain in mice

Inhibition of mechanical allodynia in neuropathic pain by TLR5-mediated A-fiber blockade

Monoclonal Antibody Targeting the Matrix Metalloproteinase 9 Prevents and Reverses Paclitaxel-Induced Peripheral Neuropathy in Mice

Neuropathic pain is constitutively suppressed in early life by anti-inflammatory neuroimmune regulation

Toll-like receptor 4 contributes to chronic itch, alloknesis, and spinal astrocyte activation in male mice

Paclitaxel-activated astrocytes produce mechanical allodynia in mice by releasing tumor necrosis factor-α and stromal-derived cell factor 1

TNF-alpha contributes to spinal cord synaptic plasticity and inflammatory pain: Distinct role of TNF receptor subtypes 1 and 2

SHANK3 Deficiency Impairs Heat Hyperalgesia and TRPV1 Signaling in Primary Sensory Neurons

The inhibition of Kir2.1 potassium channels depolarizes spinal microglial cells, reduces their proliferation, and attenuates neuropathic pain

Nociceptive neurons regulate innate and adaptive immunity and neuropathic pain through MyD88 adapter

Resolvin D3 controls mouse and human TRPV1-positive neurons and preclinical progression of psoriasis

Transcriptional Profiling of Somatostatin Interneurons in the Spinal Dorsal Horn

Lipoxin A4 inhibits microglial activation and reduces neuroinflammation and neuropathic pain after spinal cord hemisection

Dissociation and Culture of Adult Mouse Satellite Glial Cells

Targeting Nociceptive Neurons and Transient Receptor Potential Channels for the Treatment of Migraine

Peripheral serotonin receptor 2B and transient receptor potential channel 4 mediate pruritus to serotonergic antidepressants in mice

β-arrestin-2 regulates NMDA receptor function in spinal lamina II neurons and duration of persistent pain

Gene Expression Profiling of Cutaneous Injured and Non-Injured Nociceptors in SNI Animal Model of Neuropathic Pain

Transient Receptor Potential Channel 4 Small-Molecule Inhibition Alleviates Migraine-Like Behavior in Mice

Venom Peptide Toxins Targeting the Outer Pore Region of Transient Receptor Potential Vanilloid 1 in Pain: Implications for Analgesic Drug Development

Distinct ASIC currents are expressed in rat putative nociceptors and are modulated by nerve injury

Unconventional Role of Caspase-6 in Spinal Microglia Activation and Chronic Pain

Large A-Fiber Activity is Required for Microglial Proliferation and P38 MAPK Activation in the Spinal Cord: Different Effects of Resiniferatoxin and Bupivacaine on Spinal Microglial Changes after Spared Nerve Injury

Acute Morphine Activates Satellite Glial Cells and Up-Regulates IL-1β in Dorsal Root Ganglia in Mice via Matrix Metalloprotease-9

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