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Accelerating Lead Identification by High Throughput Virtual Screening: Prospective Case Studies from the Pharmaceutical Industry

Journal of chemical information and modeling, 2019-05, Vol.59 (5), p.2046-2062

2019

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Recent advances in the design of cathepsin S inhibitors

Current topics in medicinal chemistry, 2010-05, Vol.10 (7), p.717

2010

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Discovery of a Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase with Oral Anti-Inflammatory Activity

ACS medicinal chemistry letters, 2021-05, Vol.12 (5), p.782-790

2021

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Scaffold Explorer: An Interactive Tool for Organizing and Mining Structure−Activity Data Spanning Multiple Chemotypes

Journal of medicinal chemistry, 2010-07, Vol.53 (13), p.5002-5011

2010

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Discovery and SAR of novel pyrazole-based thioethers as cathepsin S inhibitors. Part 2: Modification of P3, P4, and P5 regions

Bioorganic & medicinal chemistry letters, 2010-04, Vol.20 (7), p.2375-2378

2010

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Single R-Group Polymorphisms (SRPs) and R-Cliffs: An Intuitive Framework for Analyzing and Visualizing Activity Cliffs in a Single Analog Series

Journal of chemical information and modeling, 2011-05, Vol.51 (5), p.1122-1131

2011

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Tetrahydroindazole inhibitors of bacterial type II topoisomerases. Part 2: SAR development and potency against multidrug-resistant strains

Bioorganic & medicinal chemistry letters, 2007-05, Vol.17 (10), p.2718-2722

2007

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Pyrazole-based arylalkyne Cathepsin S inhibitors. Part III: Modification of P4 region

Bioorganic & medicinal chemistry letters, 2013-02, Vol.23 (4), p.1070-1074

2013

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Selective inhibition of peripheral cathepsin S reverses tactile allodynia following peripheral nerve injury in mouse

European journal of pharmacology, 2020-08, Vol.880, p.173171, Article 173171

2020

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Medical and long-term care costs when older persons become more dependent

American journal of public health (1971), 2002-08, Vol.92 (8), p.1244-1245

2002

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Novel pyrazole derivatives as potent inhibitors of type II topoisomerases. Part 1: Synthesis and preliminary SAR analysis

Bioorganic & medicinal chemistry letters, 2007-05, Vol.17 (10), p.2723-2727

2007

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Integration of Nature and Nurture: A New Paradigm for Psychiatry

The American journal of psychiatry, 2000-08, Vol.157 (8), p.1193-1194

WIENER, JERRY M.

2000

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Orphanages: An Idea Whose Time Has Come Again?

The American journal of psychiatry, 1998-10, Vol.155 (10), p.1307-1308, Article 1307

WIENER, JERRY M.

1998

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Can social insurance for long-term care work? The experience of Germany

Health affairs (Millwood, Va.), 2000-05, Vol.19 (3), p.8-25

2000

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Can Medicaid Long-term Care Expenditures for the Elderly Be Reduced?

The Gerontologist, 1996-12, Vol.36 (6), p.800-811

WIENER, J.M

1996

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Nursing Home Work Practices and Nursing Assistants' Job Satisfaction

The Gerontologist, 2009-10, Vol.49 (5), p.611-622

2009

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Population ageing in the United States of America: implications for public programmes

International journal of epidemiology, 2002-08, Vol.31 (4), p.776-781

2002

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Why Do They Stay? Job Tenure Among Certified Nursing Assistants in Nursing Homes

The Gerontologist, 2009-04, Vol.49 (2), p.198-210

2009

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State policy on long-term care for the elderly

Health affairs (Millwood, Va.), 1998-05, Vol.17 (3), p.81-100

1998

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Nursing Home Length of Stay Patterns: Results From the 1985 National Nursing Home Survey

The Gerontologist, 1990-02, Vol.30 (1), p.16-20

1990

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State pharmaceutical assistance programs for older and disabled Americans

Health affairs (Millwood, Va.), 2001-09, Vol.20 (5), p.223

2001

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Health Care Reform in the 1990s: Where Does Long-Term Care Fit In?

The Gerontologist, 1994-06, Vol.34 (3), p.402-408

1994

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Are Consumer-Directed Home Care Beneficiaries Satisfied? Evidence From Washington State

The Gerontologist, 2007-12, Vol.47 (6), p.763-774

2007

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What Happened to Long-Term Care in the Health Reform Debate of 1993-1994? Lessons for the Future

The Milbank quarterly, 2001-01, Vol.79 (2), p.207-252

2001

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Accelerating Lead Identification by High Throughput Virtual Screening: Prospective Case Studies from the Pharmaceutical Industry

Recent advances in the design of cathepsin S inhibitors

Discovery of a Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase with Oral Anti-Inflammatory Activity

Scaffold Explorer: An Interactive Tool for Organizing and Mining Structure−Activity Data Spanning Multiple Chemotypes

Discovery and SAR of novel pyrazole-based thioethers as cathepsin S inhibitors. Part 2: Modification of P3, P4, and P5 regions

Single R-Group Polymorphisms (SRPs) and R-Cliffs: An Intuitive Framework for Analyzing and Visualizing Activity Cliffs in a Single Analog Series

Tetrahydroindazole inhibitors of bacterial type II topoisomerases. Part 2: SAR development and potency against multidrug-resistant strains

Pyrazole-based arylalkyne Cathepsin S inhibitors. Part III: Modification of P4 region

Discovery of JNJ-64264681: A Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase

Selective inhibition of peripheral cathepsin S reverses tactile allodynia following peripheral nerve injury in mouse

Medical and long-term care costs when older persons become more dependent

Novel pyrazole derivatives as potent inhibitors of type II topoisomerases. Part 1: Synthesis and preliminary SAR analysis

Integration of Nature and Nurture: A New Paradigm for Psychiatry

Orphanages: An Idea Whose Time Has Come Again?

Can social insurance for long-term care work? The experience of Germany

Can Medicaid Long-term Care Expenditures for the Elderly Be Reduced?

Nursing Home Work Practices and Nursing Assistants' Job Satisfaction

Population ageing in the United States of America: implications for public programmes

Why Do They Stay? Job Tenure Among Certified Nursing Assistants in Nursing Homes

State policy on long-term care for the elderly

Nursing Home Length of Stay Patterns: Results From the 1985 National Nursing Home Survey

State pharmaceutical assistance programs for older and disabled Americans

Health Care Reform in the 1990s: Where Does Long-Term Care Fit In?

Are Consumer-Directed Home Care Beneficiaries Satisfied? Evidence From Washington State

What Happened to Long-Term Care in the Health Reform Debate of 1993-1994? Lessons for the Future

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