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The Tec Kinases Itk and Rlk Regulate NKT Cell Maturation, Cytokine Production, and Survival

The Journal of immunology (1950), 2008-03, Vol.180 (5), p.3007-3018

2008

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The Tec kinase ITK is essential for ILC2 survival and epithelial integrity in the intestine

Nature communications, 2019-02, Vol.10 (1), p.784-784, Article 784

2019

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Tec kinase Itk in γδT cells is pivotal for controlling IgE production in vivo

Proceedings of the National Academy of Sciences - PNAS, 2009-05, Vol.106 (20), p.8308-8313

2009

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Transient expression of ZBTB32 in anti-viral CD8+ T cells limits the magnitude of the effector response and the generation of memory

PLoS pathogens, 2017-08, Vol.13 (8), p.e1006544-e1006544

2017

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Signalling through TEC kinases regulates conventional versus innate CD8 + T-cell development

Nature reviews. Immunology, 2007-06, Vol.7 (6), p.479-485

Berg, Leslie J

2007

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Interplay between IL-10, IFN-γ, IL-17A and PD-1 Expressing EBNA1-Specific CD4+ and CD8+ T Cell Responses in the Etiologic Pathway to Endemic Burkitt Lymphoma

Cancers, 2021-10, Vol.13 (21), p.5375

2021

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The Tec kinase ITK regulates thymic expansion, emigration, and maturation of γδ NKT cells

The Journal of immunology (1950), 2013-03, Vol.190 (6), p.2659-2669

2013

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Analysis of T-cell Receptor-Induced Calcium Influx in Primary Murine T-cells by Full Spectrum Flow Cytometry

Journal of visualized experiments, 2022-12 (190)

2022

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Graded levels of IRF4 regulate CD8+ T cell differentiation and expansion, but not attrition, in response to acute virus infection

The Journal of immunology (1950), 2014-06, Vol.192 (12), p.5881-5893

2014

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Itk Phosphorylation Sites Are Required for Functional Activity in Primary T Cells

The Journal of biological chemistry, 2003-09, Vol.278 (39), p.37112-37121

2003

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Intrathymic programming of effector fates in three molecularly distinct γδ T cell subtypes

Nature immunology, 2012-05, Vol.13 (5), p.511

2012

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Signaling pathways that regulate T cell development and differentiation

The Journal of immunology (1950), 2012-12, Vol.189 (12), p.5487-5488

Berg, Leslie J

2012

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Tec kinase Itk in gamma delta T cells is pivotal for controlling IgE production in vivo

Proceedings of the National Academy of Sciences - PNAS, 2009-05, Vol.106 (20), p.8308-8313

2009

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NKG2C/E Marks the Unique Cytotoxic CD4 T Cell Subset, ThCTL, Generated by Influenza Infection

The Journal of immunology (1950), 2017-02, Vol.198 (3), p.1142-1155

2017

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Type 1 interferon licenses naïve CD8 T cells to mediate anti-viral cytotoxicity

Virology (New York, N.Y.), 2016-06, Vol.493, p.52-59

2016

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c-Abl, an additional tyrosine kinase required for T cell development and function

Cell cycle (Georgetown, Tex.), 2008-12, Vol.7 (24), p.3791-3791

2008

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Subtle Defects in Pre-TCR Signaling in the Absence of the Tec Kinase Itk

The Journal of immunology (1950), 2007-12, Vol.179 (11), p.7561-7567

2007

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Strength of T Cell Receptor Signaling Strikes Again

Immunity (Cambridge, Mass.), 2009-10, Vol.31 (4), p.529-531

Berg, Leslie J.

2009

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The Transcription Factor Runx2 Is Required for Long-Term Persistence of Antiviral CD8 + Memory T Cells

ImmunoHorizons, 2018-08, Vol.2 (7), p.251-261

2018

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A Small Molecule Inhibitor of ITK and RLK Impairs Th1 Differentiation and Prevents Colitis Disease Progression

The Journal of immunology (1950), 2015-11, Vol.195 (10), p.4822-4831

2015

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The Tec Family Tyrosine Kinases Itk and Rlk Regulate the Development of Conventional CD8 + T Cells

Immunity (Cambridge, Mass.), 2006-07, Vol.25 (1), p.79-91

2006

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IFN-alpha beta and self-MHC divert CD8 T cells into a distinct differentiation pathway characterized by rapid acquisition of effector functions

The Journal of immunology (1950), 2010-08, Vol.185 (3), p.1419-1428

2010

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CD28 and ITK signals regulate autoreactive T cell trafficking

Nature medicine, 2013-12, Vol.19 (12), p.1632-1637

2013

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Innate PLZF+CD4+ alpha beta T Cells Develop and Expand in the Absence of Itk

The Journal of immunology (1950), 2014-07, Vol.193 (2), p.673-687

2014

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Development of innate CD4+ and CD8+ T cells in Itk-deficient mice is regulated by distinct pathways

The Journal of immunology (1950), 2014-07, Vol.193 (2), p.688-699

2014

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The Tec Kinases Itk and Rlk Regulate NKT Cell Maturation, Cytokine Production, and Survival

The Tec kinase ITK is essential for ILC2 survival and epithelial integrity in the intestine

Tec kinase Itk in γδT cells is pivotal for controlling IgE production in vivo

Transient expression of ZBTB32 in anti-viral CD8+ T cells limits the magnitude of the effector response and the generation of memory

Signalling through TEC kinases regulates conventional versus innate CD8 + T-cell development

Interplay between IL-10, IFN-γ, IL-17A and PD-1 Expressing EBNA1-Specific CD4+ and CD8+ T Cell Responses in the Etiologic Pathway to Endemic Burkitt Lymphoma

The Tec kinase ITK regulates thymic expansion, emigration, and maturation of γδ NKT cells

Analysis of T-cell Receptor-Induced Calcium Influx in Primary Murine T-cells by Full Spectrum Flow Cytometry

Graded levels of IRF4 regulate CD8+ T cell differentiation and expansion, but not attrition, in response to acute virus infection

Itk Phosphorylation Sites Are Required for Functional Activity in Primary T Cells

Intrathymic programming of effector fates in three molecularly distinct γδ T cell subtypes

Signaling pathways that regulate T cell development and differentiation

Tec kinase Itk in gamma delta T cells is pivotal for controlling IgE production in vivo

NKG2C/E Marks the Unique Cytotoxic CD4 T Cell Subset, ThCTL, Generated by Influenza Infection

Type 1 interferon licenses naïve CD8 T cells to mediate anti-viral cytotoxicity

c-Abl, an additional tyrosine kinase required for T cell development and function

Subtle Defects in Pre-TCR Signaling in the Absence of the Tec Kinase Itk

Strength of T Cell Receptor Signaling Strikes Again

The Transcription Factor Runx2 Is Required for Long-Term Persistence of Antiviral CD8 + Memory T Cells

A Small Molecule Inhibitor of ITK and RLK Impairs Th1 Differentiation and Prevents Colitis Disease Progression

The Tec Family Tyrosine Kinases Itk and Rlk Regulate the Development of Conventional CD8 + T Cells

IFN-alpha beta and self-MHC divert CD8 T cells into a distinct differentiation pathway characterized by rapid acquisition of effector functions

CD28 and ITK signals regulate autoreactive T cell trafficking

Innate PLZF+CD4+ alpha beta T Cells Develop and Expand in the Absence of Itk

Development of innate CD4+ and CD8+ T cells in Itk-deficient mice is regulated by distinct pathways

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