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Phosphorylation of Synaptic GTPase-activating Protein (synGAP) by Ca2+/Calmodulin-dependent Protein Kinase II (CaMKII) and Cyclin-dependent Kinase 5 (CDK5) Alters the Ratio of Its GAP Activity toward Ras and Rap GTPases

The Journal of biological chemistry, 2015-02, Vol.290 (8), p.4908-4927

2015

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Sar1 GTPase Activity Is Regulated by Membrane Curvature

The Journal of biological chemistry, 2016-01, Vol.291 (3), p.1014-1027

2016

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Unraveling the molecular mechanism of interactions of the Rho GTPases Cdc42 and Rac1 with the scaffolding protein IQGAP2

The Journal of biological chemistry, 2018-03, Vol.293 (10), p.3685-3699

2018

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The scaffold-protein IQGAP1 enhances and spatially restricts the actin-nucleating activity of Diaphanous-related formin 1 (DIAPH1)

The Journal of biological chemistry, 2020-03, Vol.295 (10), p.3134-3147

2020

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LGR5 receptor promotes cell–cell adhesion in stem cells and colon cancer cells via the IQGAP1–Rac1 pathway

The Journal of biological chemistry, 2017-09, Vol.292 (36), p.14989-15001

2017

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Site-directed Mutagenesis Shows the Significance of Interactions with Phospholipids and the G-protein OsYchF1 for the Physiological Functions of the Rice GTPase-activating Protein 1 (OsGAP1)

The Journal of biological chemistry, 2015-09, Vol.290 (39), p.23984-23996

2015

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Signaling Scaffold Protein IQGAP1 Interacts with Microtubule Plus-end Tracking Protein SKAP and Links Dynamic Microtubule Plus-end to Steer Cell Migration

The Journal of biological chemistry, 2015-09, Vol.290 (39), p.23766-23780

2015

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A Novel Role for Gab1 and SHP2 in Epidermal Growth Factor-induced Ras Activation

The Journal of biological chemistry, 2005-02, Vol.280 (7), p.5350-5360

2005

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IQGAP1-Rac1 and IQGAP1-Cdc42 Interactions: INTERFACES DIFFER BETWEEN THE COMPLEXES

The Journal of biological chemistry, 2008-01, Vol.283 (3), p.1692-1704

2008

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IQGAP1 Binds Rap1 and Modulates Its Activity

The Journal of biological chemistry, 2007-07, Vol.282 (28), p.20752-20762

2007

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Neurofibromatosis Type I Tumor Suppressor Neurofibromin Regulates Neuronal Differentiation via Its GTPase-activating Protein Function toward Ras

The Journal of biological chemistry, 2003-07, Vol.278 (29), p.26958-26969

2003

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Self-association of IQGAP1: characterization and functional sequelae

The Journal of biological chemistry, 2005-10, Vol.280 (41), p.34548

2005

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IQGAP1 Promotes Neurite Outgrowth in a Phosphorylation-dependent Manner

The Journal of biological chemistry, 2005-04, Vol.280 (14), p.13871-13878

2005

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An Alliance between Ras GTPase-activating Protein, Filamin C, and Ras GTPase-activating Protein SH3 Domain-binding Protein Regulates Myocyte Growth

The Journal of biological chemistry, 2005-07, Vol.280 (27), p.25717-25728

2005

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Hyaluronan promotes CD44v3-Vav2 interaction with Grb2-p185(HER2) and induces Rac1 and Ras signaling during ovarian tumor cell migration and growth

The Journal of biological chemistry, 2001-12, Vol.276 (52), p.48679-48692

2001

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GAP1 Family Members Constitute Bifunctional Ras and Rap GTPase-activating Proteins

The Journal of biological chemistry, 2006-04, Vol.281 (15), p.9891-9900

2006

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The Interaction of Src and RACK1 Is Enhanced by Activation of Protein Kinase C and Tyrosine Phosphorylation of RACK1

The Journal of biological chemistry, 2001-06, Vol.276 (23), p.20346-20356

2001

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Oncogenic Ras Leads to Rho Activation by Activating the Mitogen-activated Protein Kinase Pathway and Decreasing Rho-GTPase-activating Protein Activity

The Journal of biological chemistry, 2003-01, Vol.278 (5), p.2807-2818

2003

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Permease Recycling and Ubiquitination Status Reveal a Particular Role for Bro1 in the Multivesicular Body Pathway

The Journal of biological chemistry, 2003-12, Vol.278 (50), p.50732-50743

2003

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Ras GTPase-activating Protein Binds to Akt and Is Required for Its Activation

The Journal of biological chemistry, 2004-03, Vol.279 (13), p.12883-12889

2004

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Manipulation of EphB2 Regulatory Motifs and SH2 Binding Sites Switches MAPK Signaling and Biological Activity

The Journal of biological chemistry, 2003-02, Vol.278 (8), p.6111-6119

2003

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Identification of Aurora Kinases as RasGAP Src Homology 3 Domain-binding Proteins

The Journal of biological chemistry, 2002-06, Vol.277 (26), p.23742-23746

2002

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Mechanical Inhibition of RANKL Expression Is Regulated by H-Ras-GTPase

The Journal of biological chemistry, 2006-01, Vol.281 (3), p.1412-1418

2006

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Identification of an Alternatively Spliced Variant of Ca2+-promoted Ras Inactivator as a Possible Regulator of RANKL Shedding

The Journal of biological chemistry, 2005-12, Vol.280 (50), p.41700-41706

2005

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Engineering the Phosphoinositide-binding Profile of a Class I Pleckstrin Homology Domain

The Journal of biological chemistry, 2003-10, Vol.278 (41), p.39489-39496

2003

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Phosphorylation of Synaptic GTPase-activating Protein (synGAP) by Ca2+/Calmodulin-dependent Protein Kinase II (CaMKII) and Cyclin-dependent Kinase 5 (CDK5) Alters the Ratio of Its GAP Activity toward Ras and Rap GTPases

Sar1 GTPase Activity Is Regulated by Membrane Curvature

Unraveling the molecular mechanism of interactions of the Rho GTPases Cdc42 and Rac1 with the scaffolding protein IQGAP2

The scaffold-protein IQGAP1 enhances and spatially restricts the actin-nucleating activity of Diaphanous-related formin 1 (DIAPH1)

LGR5 receptor promotes cell–cell adhesion in stem cells and colon cancer cells via the IQGAP1–Rac1 pathway

Site-directed Mutagenesis Shows the Significance of Interactions with Phospholipids and the G-protein OsYchF1 for the Physiological Functions of the Rice GTPase-activating Protein 1 (OsGAP1)

Signaling Scaffold Protein IQGAP1 Interacts with Microtubule Plus-end Tracking Protein SKAP and Links Dynamic Microtubule Plus-end to Steer Cell Migration

A Novel Role for Gab1 and SHP2 in Epidermal Growth Factor-induced Ras Activation

IQGAP1-Rac1 and IQGAP1-Cdc42 Interactions: INTERFACES DIFFER BETWEEN THE COMPLEXES

IQGAP1 Binds Rap1 and Modulates Its Activity

Neurofibromatosis Type I Tumor Suppressor Neurofibromin Regulates Neuronal Differentiation via Its GTPase-activating Protein Function toward Ras

Self-association of IQGAP1: characterization and functional sequelae

IQGAP1 Promotes Neurite Outgrowth in a Phosphorylation-dependent Manner

An Alliance between Ras GTPase-activating Protein, Filamin C, and Ras GTPase-activating Protein SH3 Domain-binding Protein Regulates Myocyte Growth

Hyaluronan promotes CD44v3-Vav2 interaction with Grb2-p185(HER2) and induces Rac1 and Ras signaling during ovarian tumor cell migration and growth

GAP1 Family Members Constitute Bifunctional Ras and Rap GTPase-activating Proteins

The Interaction of Src and RACK1 Is Enhanced by Activation of Protein Kinase C and Tyrosine Phosphorylation of RACK1

Oncogenic Ras Leads to Rho Activation by Activating the Mitogen-activated Protein Kinase Pathway and Decreasing Rho-GTPase-activating Protein Activity

Permease Recycling and Ubiquitination Status Reveal a Particular Role for Bro1 in the Multivesicular Body Pathway

Ras GTPase-activating Protein Binds to Akt and Is Required for Its Activation

Manipulation of EphB2 Regulatory Motifs and SH2 Binding Sites Switches MAPK Signaling and Biological Activity

Identification of Aurora Kinases as RasGAP Src Homology 3 Domain-binding Proteins

Mechanical Inhibition of RANKL Expression Is Regulated by H-Ras-GTPase

Identification of an Alternatively Spliced Variant of Ca2+-promoted Ras Inactivator as a Possible Regulator of RANKL Shedding

Engineering the Phosphoinositide-binding Profile of a Class I Pleckstrin Homology Domain

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