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Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization

The Journal of experimental medicine, 2016-06, Vol.213 (7), p.1255-1265

2016

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HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse

PLoS genetics, 2015-10, Vol.11 (10), p.e1005620-e1005620

2015

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Clonal redemption and clonal anergy as mechanisms to balance B cell tolerance and immunity

Immunological reviews, 2019-11, Vol.292 (1), p.61-75

2019

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Calling differentially methylated regions from whole genome bisulphite sequencing with DMRcate

Nucleic acids research, 2021-11, Vol.49 (19), p.e109-e109

2021

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Roquin-2 Shares Functions with Its Paralog Roquin-1 in the Repression of mRNAs Controlling T Follicular Helper Cells and Systemic Inflammation

Immunity (Cambridge, Mass.), 2013-04, Vol.38 (4), p.669-680

2013

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SAMD9L autoinflammatory or ataxia pancytopenia disease mutations activate cell-autonomous translational repression

Proceedings of the National Academy of Sciences - PNAS, 2021-08, Vol.118 (34), p.1

2021

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DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns

Cancer cell, 2019-02, Vol.35 (2), p.297-314.e8

2019

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Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis

PLoS medicine, 2008-03, Vol.5 (3), p.e54-e54

2008

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Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells

Blood, 2006-12, Vol.108 (12), p.3777-3785

2006

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CD83 increases MHC II and CD86 on dendritic cells by opposing IL-10-driven MARCH1-mediated ubiquitination and degradation

The Journal of experimental medicine, 2011-01, Vol.208 (1), p.149-165

2011

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Murine LRBA deficiency causes CTLA‐4 deficiency in Tregs without progression to immune dysregulation

Immunology and cell biology, 2017-10, Vol.95 (9), p.775-788

2017

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Multistep Pathogenesis of Autoimmune Disease

Cell, 2007-07, Vol.130 (1), p.25-35

Goodnow, Christopher C.

2007

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Activation of the viral sensor oligoadenylate synthetase 2 (Oas2) prevents pregnancy-driven mammary cancer metastases

Breast cancer research : BCR, 2022-05, Vol.24 (1), p.31-31, Article 31

2022

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Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance

Blood, 2011-09, Vol.118 (9), p.2462-2472

2011

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RBM5 is a male germ cell splicing factor and is required for spermatid differentiation and male fertility

PLoS genetics, 2013-07, Vol.9 (7), p.e1003628-e1003628

2013

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Multistep pathogenesis of autoimmune disease

Cell, 2007-07, Vol.130 (1), p.25-35

Goodnow, Christopher C

2007

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ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes

Nature immunology, 2011-05, Vol.12 (5), p.441-449

2011

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COVID‐19, varying genetic resistance to viral disease and immune tolerance checkpoints

Immunology and cell biology, 2021-02, Vol.99 (2), p.177-191

Goodnow, Christopher C

2021

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A Point Mutation in IKAROS ZF1 Causes a B Cell Deficiency in Mice

The Journal of immunology (1950), 2021-04, Vol.206 (7), p.1505-1514

2021

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Brief Report: Identification of a Pathogenic Variant in TREX1 in Early‐Onset Cerebral Systemic Lupus Erythematosus by Whole‐Exome Sequencing

Arthritis & Rheumatology, 2014-12, Vol.66 (12), p.3382-3386

2014

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RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly

PLoS genetics, 2012-10, Vol.8 (10), p.e1002969-e1002969

2012

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Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies

mAbs, 2021-01, Vol.13 (1), p.1922134-1922134

2021

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B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8- dendritic cells require the intramembrane endopeptidase SPPL2A

The Journal of experimental medicine, 2013-01, Vol.210 (1), p.31-40

2013

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DOCK8 is critical for the survival and function of NKT cells

Blood, 2013-09, Vol.122 (12), p.2052-2061

2013

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Preponderance of CTLA4 Variation Associated With Autosomal Dominant Immune Dysregulation in the MYPPPY Motif

Frontiers in immunology, 2019-07, Vol.10, p.1544

2019

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Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization

HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse

Clonal redemption and clonal anergy as mechanisms to balance B cell tolerance and immunity

Calling differentially methylated regions from whole genome bisulphite sequencing with DMRcate

Roquin-2 Shares Functions with Its Paralog Roquin-1 in the Repression of mRNAs Controlling T Follicular Helper Cells and Systemic Inflammation

SAMD9L autoinflammatory or ataxia pancytopenia disease mutations activate cell-autonomous translational repression

DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns

Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis

Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells

CD83 increases MHC II and CD86 on dendritic cells by opposing IL-10-driven MARCH1-mediated ubiquitination and degradation

Murine LRBA deficiency causes CTLA‐4 deficiency in Tregs without progression to immune dysregulation

Multistep Pathogenesis of Autoimmune Disease

Activation of the viral sensor oligoadenylate synthetase 2 (Oas2) prevents pregnancy-driven mammary cancer metastases

Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance

RBM5 is a male germ cell splicing factor and is required for spermatid differentiation and male fertility

Multistep pathogenesis of autoimmune disease

ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes

COVID‐19, varying genetic resistance to viral disease and immune tolerance checkpoints

A Point Mutation in IKAROS ZF1 Causes a B Cell Deficiency in Mice

Brief Report: Identification of a Pathogenic Variant in TREX1 in Early‐Onset Cerebral Systemic Lupus Erythematosus by Whole‐Exome Sequencing

RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly

Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies

B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8- dendritic cells require the intramembrane endopeptidase SPPL2A

DOCK8 is critical for the survival and function of NKT cells

Preponderance of CTLA4 Variation Associated With Autosomal Dominant Immune Dysregulation in the MYPPPY Motif

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