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Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib

Proceedings of the National Academy of Sciences - PNAS, 2007-08, Vol.104 (33), p.13283-13288

2007

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Ras GTPase-Activating Protein: A Substrate and a Potential Binding Protein of the Protein-Tyrosine Kinase p56(lck)

Proceedings of the National Academy of Sciences - PNAS, 1992-04, Vol.89 (8), p.3343

1992

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Temporal Differences in the Activation of Three Classes of Non- Transmembrane Protein Tyrosine Kinases Following B-Cell Antigen Receptor Surface Engagement

Proceedings of the National Academy of Sciences - PNAS, 1994-09, Vol.91 (20), p.9524-9528

1994

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Phosphorylation Activates the Insulin Receptor Tyrosine Protein Kinase

Proceedings of the National Academy of Sciences - PNAS, 1983-06, Vol.80 (11), p.3237-3240

1983

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Crystal Structure of the Tyrosine Kinase Domain of the Hepatocyte Growth Factor Receptor c-Met and Its Complex with the Microbial Alkaloid K-252a

Proceedings of the National Academy of Sciences - PNAS, 2003-10, Vol.100 (22), p.12654-12659

2003

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Calcium/Phospholipid-Dependent Protein Kinase (Protein Kinase C) Phosphorylates and Activates Tyrosine Hydroxylase

Proceedings of the National Academy of Sciences - PNAS, 1984-12, Vol.81 (24), p.7713-7717

1984

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SLP-76 mediates and maintains activation of the Tec family kinase ITK via the T cell antigen receptor-induced association between SLP-76 and ITK

Proceedings of the National Academy of Sciences - PNAS, 2007-04, Vol.104 (16), p.6638-6643

2007

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Replacement of Lysine Residue 1030 in the Putative ATP-Binding Region of the Insulin Receptor Abolishes Insulin- and Antibody-Stimulated Glucose Uptake and Receptor Kinase Activity

Proceedings of the National Academy of Sciences - PNAS, 1987-02, Vol.84 (3), p.704-708

1987

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Detection of Multistability, Bifurcations, and Hysteresis in a Large Class of Biological Positive-Feedback Systems

Proceedings of the National Academy of Sciences - PNAS, 2004-02, Vol.101 (7), p.1822-1827

2004

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Protein Kinase C Directly Phosphorylates the Insulin Receptor in vitro and Reduces Its Protein-Tyrosine Kinase Activity

Proceedings of the National Academy of Sciences - PNAS, 1986-08, Vol.83 (16), p.5822-5824

1986

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Phosphorylation of the Nicotinic Acetylcholine Receptor by an Endogenous Tyrosine-Specific Protein Kinase

Proceedings of the National Academy of Sciences - PNAS, 1984-11, Vol.81 (22), p.6968-6972

1984

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Focal adhesion kinase promotes phospholipase C-gamma1 activity

Proceedings of the National Academy of Sciences - PNAS, 1999-08, Vol.96 (16), p.9021-9026

1999

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Insulin Activates a Tyrosine-Specific Protein Kinase in Extracts of 3T3-L1 Adipocytes and Human Placenta

Proceedings of the National Academy of Sciences - PNAS, 1982-11, Vol.79 (22), p.6792-6796

1982

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Platelet-Derived Growth Factor Stimulates Tyrosine-Specific Protein Kinase Activity in Swiss Mouse 3T3 Cell Membranes

Proceedings of the National Academy of Sciences - PNAS, 1982-07, Vol.79 (14), p.4303-4307

1982

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Stimulation by Phospholipids of a Protein-Tyrosine-Phosphatase Containing Two src Homology 2 Domains

Proceedings of the National Academy of Sciences - PNAS, 1993-05, Vol.90 (9), p.4251-4255

1993

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Modification of Ser59 in the unique N-terminal region of tyrosine kinase p56lck regulates specificity of its Src homology 2 domain

Proceedings of the National Academy of Sciences - PNAS, 1995-06, Vol.92 (13), p.5778-5782

1995

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Purification and characterization of recombinant human p50csk protein-tyrosine kinase from an Escherichia coli expression system overproducing the bacterial chaperones GroES and GroEL

Proceedings of the National Academy of Sciences - PNAS, 1995-02, Vol.92 (4), p.1048-1052

1995

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Mn2+-Binding Properties of a Recombinant Protein-Tyrosine Kinase Derived from the Human Insulin Receptor

Proceedings of the National Academy of Sciences - PNAS, 1990-04, Vol.87 (7), p.2805-2809

1990

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Stimulation of human monocytes with macrophage colony-stimulating factor induces a Grb2-mediated association of the focal adhesion kinase pp125FAK and dynamin

Proceedings of the National Academy of Sciences - PNAS, 1995-06, Vol.92 (13), p.6132-6136

1995

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A Point Mutation at Tyrosine-809 in the Human Colony-Stimulating Factor 1 Receptor Impairs Mitogenesis Without Abrogating Tyrosine Kinase Activity, Association With Phosphatidylinositol 3-Kinase, or Induction of c-Fos and JunB Genes

Proceedings of the National Academy of Sciences - PNAS, 1990-09, Vol.87 (17), p.6738-6742

1990

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A biochemical mechanism for the oncogenic potential of the p110b catalytic subunit of phosphoinositide 3-kinase

Proceedings of the National Academy of Sciences - PNAS, 2010-11, Vol.107 (46), p.19897-19902

2010

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Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases

Proceedings of the National Academy of Sciences - PNAS, 1998-05, Vol.95 (10), p.5724-5729

1998

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2,3,7,8-tetrachlorodibenzo-p-dioxin Causes Increases in Expression of c-erb-A and Levels of Protein-tyrosine Kinases in Selected Tissues of Responsive Mouse Strains

Proceedings of the National Academy of Sciences - PNAS, 1988-06, Vol.85 (12), p.4128-4132

1988

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Interleukin-2 induces beta2-integrin-dependent signal transduction involving the focal adhesion kinase-related protein B (fakB)

Proceedings of the National Academy of Sciences - PNAS, 1998-06, Vol.95 (12), p.6959-6964

1998

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In vitro Tyrosine Phosphorylation Studies on RAS Proteins and Calmodulin Suggest that Polylysine-Like Basic Peptides or Domains May be Involved in Interactions between Insulin Receptor Kinase and its Substrate

Proceedings of the National Academy of Sciences - PNAS, 1989-10, Vol.86 (19), p.7306-7310

1989

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Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib

Ras GTPase-Activating Protein: A Substrate and a Potential Binding Protein of the Protein-Tyrosine Kinase p56(lck)

Temporal Differences in the Activation of Three Classes of Non- Transmembrane Protein Tyrosine Kinases Following B-Cell Antigen Receptor Surface Engagement

Phosphorylation Activates the Insulin Receptor Tyrosine Protein Kinase

Crystal Structure of the Tyrosine Kinase Domain of the Hepatocyte Growth Factor Receptor c-Met and Its Complex with the Microbial Alkaloid K-252a

Calcium/Phospholipid-Dependent Protein Kinase (Protein Kinase C) Phosphorylates and Activates Tyrosine Hydroxylase

SLP-76 mediates and maintains activation of the Tec family kinase ITK via the T cell antigen receptor-induced association between SLP-76 and ITK

Replacement of Lysine Residue 1030 in the Putative ATP-Binding Region of the Insulin Receptor Abolishes Insulin- and Antibody-Stimulated Glucose Uptake and Receptor Kinase Activity

Detection of Multistability, Bifurcations, and Hysteresis in a Large Class of Biological Positive-Feedback Systems

Protein Kinase C Directly Phosphorylates the Insulin Receptor in vitro and Reduces Its Protein-Tyrosine Kinase Activity

Phosphorylation of the Nicotinic Acetylcholine Receptor by an Endogenous Tyrosine-Specific Protein Kinase

Focal adhesion kinase promotes phospholipase C-gamma1 activity

Insulin Activates a Tyrosine-Specific Protein Kinase in Extracts of 3T3-L1 Adipocytes and Human Placenta

Platelet-Derived Growth Factor Stimulates Tyrosine-Specific Protein Kinase Activity in Swiss Mouse 3T3 Cell Membranes

Stimulation by Phospholipids of a Protein-Tyrosine-Phosphatase Containing Two src Homology 2 Domains

Modification of Ser59 in the unique N-terminal region of tyrosine kinase p56lck regulates specificity of its Src homology 2 domain

Purification and characterization of recombinant human p50csk protein-tyrosine kinase from an Escherichia coli expression system overproducing the bacterial chaperones GroES and GroEL

Mn2+-Binding Properties of a Recombinant Protein-Tyrosine Kinase Derived from the Human Insulin Receptor

Stimulation of human monocytes with macrophage colony-stimulating factor induces a Grb2-mediated association of the focal adhesion kinase pp125FAK and dynamin

A Point Mutation at Tyrosine-809 in the Human Colony-Stimulating Factor 1 Receptor Impairs Mitogenesis Without Abrogating Tyrosine Kinase Activity, Association With Phosphatidylinositol 3-Kinase, or Induction of c-Fos and JunB Genes

A biochemical mechanism for the oncogenic potential of the p110b catalytic subunit of phosphoinositide 3-kinase

Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases

2,3,7,8-tetrachlorodibenzo-p-dioxin Causes Increases in Expression of c-erb-A and Levels of Protein-tyrosine Kinases in Selected Tissues of Responsive Mouse Strains

Interleukin-2 induces beta2-integrin-dependent signal transduction involving the focal adhesion kinase-related protein B (fakB)

In vitro Tyrosine Phosphorylation Studies on RAS Proteins and Calmodulin Suggest that Polylysine-Like Basic Peptides or Domains May be Involved in Interactions between Insulin Receptor Kinase and its Substrate

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