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Preclinical Pharmacokinetics and Pharmacodynamics of DISC-0998, a Humanized Anti-Hemojuvelin (HJV) Monoclonal Antibody to Suppress the Production of Hepcidin
Blood, 2022-11, Vol.140 (Supplement 1), p.8184-8185
2022
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DISC-0974, an Anti-Hemojuvelin Antibody, Reduces Hepcidin and Mobilizes Iron in Healthy Volunteers
Blood, 2022-11, Vol.140 (Supplement 1), p.5339-5340
2022
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A CD117-Amanitin Antibody Drug Conjugate (ADC) Effectively Depletes Human and Non-Human Primate Hematopoietic Stem and Progenitor Cells (HSPCs): targeted Non-Genotoxic Conditioning for Bone Marrow Transplant
Biology of blood and marrow transplantation, 2019-03, Vol.25 (3), p.S29-S30
2019
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Bispecific antibody complex pre-targeting and targeted delivery of polymer drug conjugates for imaging and therapy in dual human mammary cancer xenografts: Targeted polymer drug conjugates for cancer diagnosis and therapy
European journal of nuclear medicine and molecular imaging, 2014-08, Vol.41 (8), p.1603-1616
2014
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A Single Dose of CD117 Antibody Drug Conjugate Enables Autologous Gene-Modified Hematopoietic Stem Cell Transplant (Gene Therapy) in Nonhuman Primates
Blood, 2019-11, Vol.134 (Supplement_1), p.610-610
2019
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Non-Genotoxic Conditioning for Hematopoietic Stem Cell Transplant Using a Human Antibody Drug Conjugate Targeting C-KIT
Blood, 2017-12, Vol.130, p.1894-1894
2017
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Single Doses of Antibody Drug Conjugates (ADCs) Targeted to CD117 or CD45 Have Potent In Vivo Anti-Leukemia Activity and Survival Benefit in Patient Derived AML Models
Blood, 2018-11, Vol.132 (Supplement 1), p.3316-3316
2018
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Targeting CD45 with an Amanitin Antibody-Drug Conjugate Effectively Depletes Human HSCs and Immune Cells for Transplant Conditioning
Blood, 2018-11, Vol.132 (Supplement 1), p.4526-4526
2018
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CD117-Amanitin Antibody Drug Conjugates Effectively Deplete Human and Non-Human Primate HSCs: Proof of Concept As a Targeted Strategy for Conditioning Patients for Bone Marrow Transplant
Blood, 2018-11, Vol.132 (Supplement 1), p.3314-3314
2018
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Reduction of the cardiotoxicity of Doxorubicin: Demonstration by in vivo imaging with Bispecific antibody/radiolabeled negatively charged polymers
2012
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A Non-Genotoxic Anti-CD117 Antibody Drug Conjugate (ADC) Designed for Patient Conditioning Prior to Stem Cell Transplant and HSC-Based Gene Therapy Has a Broad Therapeutic Window across Species
Biology of blood and marrow transplantation, 2020-03, Vol.26 (3), p.S35-S36
2020
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A Single Dose of CD117 Antibody Drug Conjugate Enables Hematopoietic Stem Cell Based Gene Therapy in Nonhuman Primates
Biology of blood and marrow transplantation, 2020-03, Vol.26 (3), p.S6-S6
2020
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Non-Genotoxic Conditioning Using Amanitin Antibody-Drug Conjugates Targeting CD45 Effectively Deplete Human and Non-Human Primate Hematopoietic Stem Cells and Immune Cells
Biology of blood and marrow transplantation, 2019-03, Vol.25 (3), p.S32-S32
2019
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Single Doses of Antibody Drug Conjugates (ADCs) Targeted to CD117 or CD45 Have Potent In Vivo Anti-Leukemia Activity and Survival Benefit in Patient Derived AML Models
Biology of blood and marrow transplantation, 2019-03, Vol.25 (3), p.S100-S101
2019
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Single Doses of Antibody Drug Conjugates (ADCs) Targeted to CD117 or CD45 Have Potent In Vivo Anti-Leukemia Activity and Survival Benefit in Patient Derived AML Models
Biology of blood and marrow transplantation, 2019-03, Vol.25 (3), p.S100-S100
2019
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A Non-Genotoxic Antibody Drug Conjugate Targeting C-Kit for Hematopoietic Stem Cell Transplant Conditioning
Biology of blood and marrow transplantation, 2018-03, Vol.24 (3), p.S47-S48
2018
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23 - A Non-Genotoxic Antibody Drug Conjugate Targeting C-Kit for Hematopoietic Stem Cell Transplant Conditioning
Biology of blood and marrow transplantation, 2018-03, Vol.24 (3), p.S47-S48
2018
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Algorithms: Big Data, Optimization Techniques, Cyber Security
1, 2024
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CRISPR/Cas techniques used in plant disease management
Biocontrol Agents for Improved Agriculture, 2024
2024
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Carbon stock inventory and biomass production in different land use systems of Northwestern Himalaya
Climate Change in the Himalayas, 2023
2023
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