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Synthesis, Stability, and Biological Studies of Fluorinated Analogues of Thromboxane A2

ACS central science, 2020-06, Vol.6 (6), p.995-1000

2020

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Aquaporin-1 regulates platelet procoagulant membrane dynamics and in vivo thrombosis

JCI insight, 2018-05, Vol.3 (10)

2018

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In-depth PtdIns(3,4,5)P3 signalosome analysis identifies DAPP1 as a negative regulator of GPVI-driven platelet function

Blood advances, 2017-06, Vol.1 (14), p.918-932

2017

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Integrin αIIbβ3 outside-in signaling

Blood, 2017-10, Vol.130 (14), p.1607-1619

2017

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204Effects of adiposity on the human proteome: Mendelian randomization study using individual-level data

International journal of epidemiology, 2021-09, Vol.50 (Supplement_1)

2021

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Insulin-like growth factor-1 potentiates platelet activation via the IRS/PI3Kalpha pathway

Blood, 2007-12, Vol.110 (13), p.4243-4252

Hers, Ingeborg

2007

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Difluorinated thromboxane A 2 reveals crosstalk between platelet activatory and inhibitory pathways by targeting both the TP and IP receptors

British journal of pharmacology, 2024-10, Vol.181 (19), p.3685-3699

2024

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The Phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P3) Binder Rasa3 Regulates Phosphoinositide 3-kinase (PI3K)-dependent Integrin αIIbβ3 Outside-in Signaling

The Journal of biological chemistry, 2017-02, Vol.292 (5), p.1691-1704

2017

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Is JAK2V617F finally off the hook?

Blood, 2014-08, Vol.124 (7), p.992-993

2014

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Alterations in platelet proteome signature and impaired platelet integrin α IIb β 3 activation in patients with COVID-19

Journal of thrombosis and haemostasis, 2023-05, Vol.21 (5), p.1307

2023

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Carbonic Anhydrase Inhibitors suppress platelet procoagulant responses and in vivo thrombosis

Platelets (Edinburgh), 2020-10, Vol.31 (7), p.853-859

2020

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Integrin α IIb β 3 outside-in signaling

Blood, 2017-10, Vol.130 (14), p.1607

2017

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Protein Kinase C-mediated Phosphorylation and Activation of PDE3A Regulate cAMP Levels in Human PlateletsS

The Journal of biological chemistry, 2009-05, Vol.284 (18), p.12339-12348

2009

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Synthesis, Stability, and Biological Studies of Fluorinated Analogues of Thromboxane A 2

ACS central science, 2020-06, Vol.6 (6), p.995-1000

2020

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Dysfunction of the PI3 kinase/Rap1/integrin αIIbβ3 pathway underlies ex vivo platelet hypoactivity in essential thrombocythemia

Blood, 2013-02, Vol.121 (7), p.1209-1219

2013

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Dual Regulation of Glycogen Synthase Kinase 3 (GSK3)α/β by Protein Kinase C (PKC)α and Akt Promotes Thrombin-mediated Integrin αIIbβ3 Activation and Granule Secretion in Platelets

The Journal of biological chemistry, 2013-02, Vol.288 (6), p.3918-3928

2013

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Fyn and Lyn phosphorylate the Fc receptor γ chain downstream of glycoprotein VI in murine platelets, and Lyn regulates a novel feedback pathway

Blood, 2000-12, Vol.96 (13), p.4246-4253

2000

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Evidence against a direct role of the integrin α2β1 in collagen‐induced tyrosine phosphorylation in human platelets

European journal of biochemistry, 2000-04, Vol.267 (7), p.2088-2097

2000

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mTORC2 protein complex-mediated Akt (Protein Kinase B) Serine 473 Phosphorylation is not required for Akt1 activity in human platelets [corrected]

The Journal of biological chemistry, 2011-07, Vol.286 (28), p.24553-24560

2011

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Dysfunction of the PI3 kinase/Rap1/integrin α(IIb)β(3) pathway underlies ex vivo platelet hypoactivity in essential thrombocythemia

Blood, 2013-02, Vol.121 (7), p.1209

2013

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Inhibition of Platelet Integrin α IIb β 3 by Peptides That Interfere With Protein Kinases and the β 3 Tail

Arteriosclerosis, thrombosis, and vascular biology, 2000-06, Vol.20 (6), p.1651-1660

2000

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Differential Involvement of Tyrosine and Serine/Threonine Kinases in Platelet Integrin α IIb β 3 Exposure

Arteriosclerosis, thrombosis, and vascular biology, 1998-03, Vol.18 (3), p.404-414

1998

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Immunoblotting (Western)

Essential Guide to Reading Biomedical Papers, 2012, p.137-145

2012

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Exposure of ligand-binding sites on platelet integrin alpha IIB/beta 3 by phosphorylation of the beta 3 subunit

Biochemical journal, 1996-03, Vol.314 ( Pt 3) (3), p.769-779

1996

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Synthesis, Stability, and Biological Studies of Fluorinated Analogues of Thromboxane A2

Aquaporin-1 regulates platelet procoagulant membrane dynamics and in vivo thrombosis

In-depth PtdIns(3,4,5)P3 signalosome analysis identifies DAPP1 as a negative regulator of GPVI-driven platelet function

Integrin αIIbβ3 outside-in signaling

204Effects of adiposity on the human proteome: Mendelian randomization study using individual-level data

Insulin-like growth factor-1 potentiates platelet activation via the IRS/PI3Kalpha pathway

Difluorinated thromboxane A 2 reveals crosstalk between platelet activatory and inhibitory pathways by targeting both the TP and IP receptors

The Phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P3) Binder Rasa3 Regulates Phosphoinositide 3-kinase (PI3K)-dependent Integrin αIIbβ3 Outside-in Signaling

Is JAK2V617F finally off the hook?

Alterations in platelet proteome signature and impaired platelet integrin α IIb β 3 activation in patients with COVID-19

Carbonic Anhydrase Inhibitors suppress platelet procoagulant responses and in vivo thrombosis

Integrin α IIb β 3 outside-in signaling

Protein Kinase C-mediated Phosphorylation and Activation of PDE3A Regulate cAMP Levels in Human PlateletsS

Synthesis, Stability, and Biological Studies of Fluorinated Analogues of Thromboxane A 2

Dysfunction of the PI3 kinase/Rap1/integrin αIIbβ3 pathway underlies ex vivo platelet hypoactivity in essential thrombocythemia

Dual Regulation of Glycogen Synthase Kinase 3 (GSK3)α/β by Protein Kinase C (PKC)α and Akt Promotes Thrombin-mediated Integrin αIIbβ3 Activation and Granule Secretion in Platelets

Fyn and Lyn phosphorylate the Fc receptor γ chain downstream of glycoprotein VI in murine platelets, and Lyn regulates a novel feedback pathway

Evidence against a direct role of the integrin α2β1 in collagen‐induced tyrosine phosphorylation in human platelets

mTORC2 protein complex-mediated Akt (Protein Kinase B) Serine 473 Phosphorylation is not required for Akt1 activity in human platelets [corrected]

Dysfunction of the PI3 kinase/Rap1/integrin α(IIb)β(3) pathway underlies ex vivo platelet hypoactivity in essential thrombocythemia

Inhibition of Platelet Integrin α IIb β 3 by Peptides That Interfere With Protein Kinases and the β 3 Tail

Differential Involvement of Tyrosine and Serine/Threonine Kinases in Platelet Integrin α IIb β 3 Exposure

Immunoblotting (Western)

Exposure of ligand-binding sites on platelet integrin alpha IIB/beta 3 by phosphorylation of the beta 3 subunit

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